Navigation Links
Is yakult helpful in the treatment of irritable bowel syndrome?

SIBO is a common feature in IBS and in fact may be directly related to the genesis of IBS symptoms. An ERBHAL on a lactulose breath test may indicate SIBO. Antibiotics and elemental diets have been shown to be effective in treating SIBO, but the efficacy of probiotics is untested. A pilot study was undertaken to determine the effect of L. strain Shirota (Yakult(R)) on intestinal fermentation patterns of IBS patients. After 6 week of treatment with 1 x 65 mL dose of Yakult(R) daily, 9 of 14 patients (64%) completing the study had reversal of ERBHAL, with the median time of first rise increasing from 45 to 75 min (P = 0.03). Furthermore, symptoms improved in those in whom ERBHAL was corrected. The results indicate that Yakult(R) alters fermentation patterns suggesting a reduction in SIBO. ERBHAL can also indicate rapid small intestinal transit and therefore, in order to confirm the effect of Yakult(R) on SIBO, future studies will include monitoring of transit time in addition to placebo control.

A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team was led by Peter Gibson and his colleagues at Monash University, Box Hill Hospital. The pilot trial was undertaken to determine whether a probiotic could have an effect on SIBO. Currently, SIBO is managed by antibiotics and/or elemental diets, the side effects and practicalities of which make them undesirable options. Probiotics may provide a safe alternative. The results of the pilot trial warrant a well powered, double blind, placebo-controlled trial.

The effect of probiotics on SIBO had not previously been investigated, but after taking Yakult(R) daily for 6 wk, there was a significant shift in the time of first rise on the lactulose breath test indicating a reduction in SIBO. If these findings are confirmed by further research, Yakult(R) may be a safe and effective alternative for the management of this patient group.


Contact: Lai-Fu Li
World Journal of Gastroenterology

Related biology news :

1. Statin does not appear helpful for children with learning disabilities caused by genetic disorder
2. Study confirms that low-calorie sweeteners are helpful in weight control
3. Fish oil -- helpful or harmful?
4. Breastfeeding boost IQ in infants with helpful genetic variant
5. New once-a-week treatment for type 2 diabetes developed by Mount Sinai researcher
6. Landmark study opens door to new cancer, aging treatments
7. Common treatment to delay labor decreases preterm infants risk for cerebral palsy
8. UC Davis researchers define characteristics, treatment options for XXYY syndrome
9. Why a common treatment for prostate cancer ultimately fails
10. Biodegradable polymers show promise for improving treatment of acute inflammatory diseases
11. Childrens national co-leads nationwide study of landmark sickle cell treatment
Post Your Comments:
(Date:10/5/2015)... 5, 2015 ) ... NXT-ID, Inc. (NASDAQ: NXTD ), a biometric authentication ... --> ) releases the following ... NXTD ), a biometric authentication company focused on the ... Group ( ) releases the following ...
(Date:9/30/2015)... -- The global glucose monitoring device and diabetes management market is ... report on the industry from Kalorama Information. Sales in the traditional ... by continuous glucose monitoring and sensor segment, according to the ... products in its latest report, The Global Glucose Monitoring ... , ...
(Date:9/28/2015)... -- The global image sensors market ... by 2020, growing at a CAGR of 4.6% from ... (BSI) technique to improve picture quality are expected to ...      (Logo: , The light falls ... and, thus, reduce the noise interference and increase picture ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... Calif. and BRUSSELS , Oct. ... (Euronext Brussels: UCB) today presented additional findings from an exploratory ... The findings were presented today in an oral plenary ... (ASBMR) 2015 Annual Meeting in Seattle . ... --> The small exploratory sub-study data showed ...
(Date:10/12/2015)... Oct. 12, 2015 This report covers the ... cell type, products, applications, end-user markets and geographic segmentation. ... The global cell expansion market generated revenue of ... reach revenues of $9.7 billion in 2015 and $22.0 ... (CAGR) of 17.8% from 2015 to 2020. This ...
(Date:10/12/2015)... ANNAPOLIS, Maryland , 12 de octubre de 2015 ... O. Matsui (D-CA) llegó a un récord en el ... tercera edición anual de la International Plasma Awareness Week ... octubre. La IPAW está patrocinada por la Plasma ... estando diseñada para: , Aumentar la ...
(Date:10/12/2015)... 12, 2015 LabStyle Innovations Corp. ... Solution, today announced its Medical Director, Dr. Moshe ... MobiHealth,s 5th EAI International Conference on Wireless Mobile ... innovations in mobile and wireless technologies," the conference will ... from October 14 - 16, 2015. The conference is ...
Breaking Biology Technology: