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Is estrogen going to your head?
Date:9/8/2011

Girls are growing up faster than ever and not only when it comes to their taste in fashion and music. Their bodies are reaching puberty at an increasingly earlier age, and this trend to rapid maturity continues through women's adult lives. That's bad news, according to Tel Aviv University researchers. Women today are more likely to develop Hyperostosis Frontalis Interna (HFI), a hormonal condition once typically found in post-menopausal women, earlier and more frequently than the female population a century ago.

Women's hormonal balances are changing and taking a physical toll, says Prof. Israel Hershkovitz and his graduate student Hila May of TAU's Sackler Faculty of Medicine, together with Dr. Natan Peled of Carmel Medical Center in Haifa. That balance is being affected by the hormones we now consume in our food and by our changing fertility patterns, such as having children later in life. Women today are 2.5 times more likely to develop HFI than they were 100 years ago, the study found.

Their research recently appeared in the American Journal of Human Biology.

Sounding the alarm

HFI occurs when a hormonal imbalance leads to the growth of lesions, or bone masses, in the inner skull. This may lead to symptoms such as chronic headaches, weight gain, and thyroid irregularities, and is suspected to have multiple causes, including lifestyle, fertility habits, nutrition, and environment.

To track the growing prevalence of HFI, Prof. Hershkovitz and fellow researchers compared 992 historic female skulls from museum collections aged 20 to 90 years with CT scans of 568 living female participants ranging from 20 to 103 years old. Not only was prevalence of HFI found to be 2.5 times higher in the latter group, but the researchers also discovered that the average age of women who suffered from HFI had fallen drastically.

An age-dependent condition, HFI was once known to primarily strike post-menopaus
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Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

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