Navigation Links
Irritating smells alert special cells, NIH-funded study finds
Date:3/3/2008

If you cook, you know. Chop an onion and you risk crying over your cutting board as a burning sensation overwhelms your eyes and nose. Scientists do not know why certain chemical odors, like onion, ammonia and paint thinner, are so highly irritating, but new research in mice has uncovered an unexpected role for specific nasal cavity cells. Researchers funded by the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health, describe this work in the March issue of the Journal of Neurophysiology, now available online.

Weihong Lin, Ph.D., of the University of Colorado Denver School of Medicine and University of Maryland, Baltimore County, led the study which discovered that a particular cell, abundant near the entry of many animal noses, plays a crucial and previously unknown role in transmitting irritating and potentially dangerous odors. Dr. Lin and colleagues from both universities plus the Mount Sinai School of Medicine identified the role of this solitary chemosensory cell in transmitting irritating chemical odors in the noses of mice.

Scientists have found similar solitary chemosensory cells in the nasal cavities, airways and gastrointestinal tracts of many mammals as well as fish, frogs and alligators; they think it is likely that they are also present in humans, explains Thomas Finger, Ph.D., one of the senior co-authors at the University of Colorado Denver.

Prior to this work, scientists who study smell and taste thought that irritating odors directly stimulated the trigeminal nerve, which senses touch, temperature and pain throughout the head region, including the delicate membranes that line the inside of the nose. The research team, under the guidance of Diego Restrepo, Ph.D., found that solitary chemosensory cells scattered in the epithelium inside the front of the nose respond to high levels of irritating odors and relay signals to trigeminal nerve fibers.

<
'/>"/>
Contact: Linda Joy
ljoy@mail.nih.gov
301-496-7243
NIH/National Institute on Deafness and Other Communication Disorders
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Gene determines whether male body odor smells pleasant
2. Telemedicine: Health alert via satellite
3. Alcohol and sleep restriction can affect young mens alertness and driving performance
4. Enzyme alerts cells powerful army to repair DNA damage
5. Corporate Safe Specialists Smart Safes Capture Evidence in Robbery and Theft
6. Weird water: Discovery challenges long-held beliefs about waters special properties
7. World-leading journal publishes special issue on UN/GA
8. Corporate Safe Specialists Announces Addition to Sales Team
9. A special issue of the International Journal of Plant Sciences
10. K-State specialist in tick-borne pathogens receives $1.8 million grant
11. Corporate Safe Specialists Announces Additions to R&D Team
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/29/2014)... An innovative workflow reveals new research potential of the ... recently published article in the Biodiversity Data ... BOLD in tabular format and imported these into a ... Writting Tool (PWT). Data were used to study ... wasps from the Microgastrinae subfamily. , BOLD is originally ...
(Date:10/29/2014)... new study on a large cohort of kidney cancer ... of the disease -- and reveals an apparent link ... cancer, particularly in Romania. , The research, by an ... and Genome Quebec Innovation Centre in Montreal, underscores the ... acid. The compound, found in plants of the Aristolochia ...
(Date:10/28/2014)... the National University of Singapore (NUS) have discovered a ... and laying direct developing eggs in live bamboo with ... spotted bush frog ( Raorchestes chalazodes ). This ... species known to adopt this novel reproductive strategy. The ... Biological Journal of the Linnean Society , in ...
Breaking Biology News(10 mins):Go straight and publish: From Barcode of Life Data Systems to scholarly publishing systems 2Study sheds light on genetic architecture of kidney cancer 2Study sheds light on genetic architecture of kidney cancer 3NUS researchers discover for the first time that a rare bush frog breeds in bamboo 2NUS researchers discover for the first time that a rare bush frog breeds in bamboo 3
... CORVALLIS, Ore. Marine resource managers often gauge the health ... of predator-prey relationships in the Bering Sea found that it ... it,s how densely they are aggregated. It,s more ... need to balance how much energy they expend in searching ...
... HOUSTON (Jan. 3, 2013) Plasmonic gold nanoparticles ... researchers have found a way to selectively heat diverse ... industry. Rice scientists led by Dmitri Lapotko and ... 19th century as gold colloids, heat up at near-infrared ...
... , a professor of mathematics at the University of ... receive the 2013 Levi L. Conant Prize from the American Mathematical ... prize recognizes the best expository research paper published in either the ... the AMS in the preceding five years. Baez and ...
Cached Biology News:Bering Sea study finds prey density more important to predators than biomass 2Bering Sea study finds prey density more important to predators than biomass 3Nanoparticles reach new peaks 2Nanoparticles reach new peaks 3UC Riverside mathematicians recognized by American Mathematical Society 2
(Date:10/30/2014)... A solution to one of the key challenges in ... University of Sussex physicists. , In a paper published ... Barry Garraway and colleagues show how to make a ... , Quantum technology devices, such as high-precision sensors and ... interaction of atoms. But the methods for trapping these ...
(Date:10/27/2014)... October 27, 2014 The ... produce, exhibit and sell its artificial "lower limb", ... their patent.      (Photo: http://photos.prnewswire.com/prnh/20141027/713097 ... of fighting, the definitive judgement has arrived: Roadrunnerfoot, ... innovative and accessible hi-tech prostheses with composite materials, ...
(Date:10/27/2014)... BOSTON, MA (PRWEB) October 27, 2014 ... and profit. SoundConnect , an industry leading ... for its partners and agents to deliver cloud-based ... and accelerate growth opportunities. , With SoundConnect’s ... for every twenty-five video and/or web conferencing licenses ...
(Date:10/27/2014)... Janssen Biotech, Inc. and the Crohn,s ... the launch of Get Your Full ... designed to provide resources for people living with ... of nutrition and appropriate therapy in managing IBD. ... with this release, please click: http://www.multivu.com/players/English/7261131-janssen-ccfa-get-your-full-course-for-ibd-wellness-with-sunny-anderson/ ...
Breaking Biology Technology:Italian Lower Limb Prosthesis Company Wins Lawsuit Against German Giant Ottobock 2SoundConnect Unveils Q4 Partner Incentives 2Celebrity Cook Sunny Anderson Teams Up With Janssen And Crohn's & Colitis Foundation Of America To Launch Educational Campaign 2Celebrity Cook Sunny Anderson Teams Up With Janssen And Crohn's & Colitis Foundation Of America To Launch Educational Campaign 3Celebrity Cook Sunny Anderson Teams Up With Janssen And Crohn's & Colitis Foundation Of America To Launch Educational Campaign 4
... a network of tiny sensors as small as dewdrops ... intruder. Scattered outdoors on rocks, fence posts and doorways, ... are a completely new and cost-effective system for safeguarding and ... his Tel Aviv University Faculty of Engineering team drew upon ...
... in key leadership expertise to strengthen its European business ... SIRO ClinPharm Pvt. Ltd., a leading multinational full ... of Scott L. Spector as President Strategic Operations Europe. ... office of Omega Mediation . Mr. Spector brings ...
... faced H1N1 Flu OutbreaksJAMAICA, N.Y., May 26 ... of SANYO North America, announces the donation of ... level of safe, healthy air for areas where ... The first recipients to receive the donated SANYO ...
Cached Biology Technology:Intruder alert: Tel Aviv University's 'Smart Dew' will find you! 2SIRO Group Appoints Scott L. Spector as President, Strategic Operations, for its European Business 2SANYO Donates Air Purification Systems Effective Against Flu Viruses to New York Airports and Schools 2SANYO Donates Air Purification Systems Effective Against Flu Viruses to New York Airports and Schools 3SANYO Donates Air Purification Systems Effective Against Flu Viruses to New York Airports and Schools 4
... The Biometra TProfessional Thermocycler combines top ... silver block achieves high speed and unparalleled ... graphical display providing programming in a spreadsheet ... High Performance Smart Lid opens on the ...
... Vesicles Isolation Kit provides all the ... synaptic vesicle fraction. The isolation procedure ... the synaptosomes, and differential centrifugation followed ... kit also contains an antibody specific ...
... extraction of DNA fragments from 150 bp to > ... uses GelMelt solution to dissolve the gel slice, followed ... in a spin column format. After a wash step, ... spin column can bind up to 20 g DNA. ...
This kit is designed to select cells labeled with fluorescein isothiocyanate- (FITC-) conjugated antibodies. Kit includes reagents for labeling 3 x 10 9 cells and EasySep magnet....
Biology Products: