Navigation Links
Ironing out the link between H. pylori infection and gastric cancer
Date:12/21/2012

H. pylori frequently causes gastric ulcers and is also one of the greatest risk factors for gastric cancer. H. pylori infection is also associated with another gastric cancer risk factor, iron deficiency. In this issue of the Journal of Clinical Investigation, researchers led by Richard Peek at Vanderbilt University investigated the influence of iron on H. pylori-induced gastric cancer. Peek and colleagues found that low iron accelerated the development of H. pylori-associated cancerous lesions in gerbils. Further, H. pylori strains isolated from a human population at high risk for gastric cancer were more virulent and produced greater inflammation if they came from patients with low iron levels. In an accompanying article, El-Omar Emad of Aberdeen University discusses how iron levels could be used to identify patients that are at a higher risk for gastric cancer after H. pylori infection.

TITLE:
Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans

AUTHOR CONTACT:
Richard M. Peek, Jr.
Vanderbilt University School of Medicine, Nashville, TN, USA
Phone: 615-322-5200; Fax: 615-343-6229; E-mail: richard.peek@vanderbilt.edu

View this article at: http://www.jci.org/articles/view/64373?key=95552f8a58ca300dd6bc

ACCOMPANYING ARTICLE

TITLE:
Iron deficiency and H. pylori-induced gastric cancer: too little, too bad

AUTHOR CONTACT:
Emad El-Omar
Aberdeen University, Foresterhill, Aberdeen, , GBR
Phone: +44 (0)1224 437548; E-mail: e.el-omar@abdn.ac.uk

View this article at: http://www.jci.org/articles/view/67200?key=98b2d035a72beb6365c9


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Related biology news :

1. The findings between DNMs and autism provides global view of mutability on human diseases
2. New menhaden study will help identify balance between fishing and preserving Bay forage fish
3. Dark Ages scourge enlightens modern struggle between man and microbes
4. Multiple sclerosis immune exchange between brain and blood is uncovered
5. Researchers study links between conflict and fisheries in East Africa
6. Mongolia and the Altai Mountains: Origins of genetic blending between Europeans and Asians
7. Bridging the gap between genomics and education
8. Pigs look healthy but test positive for flu at fairs; transmission seen between pigs and humans
9. New study confirms erroneous link between XMRV and prostate cancer-contamination was the cause
10. UCLA researchers discover missing link between stem cells and immune system
11. Menopause evolved to prevent competition between in-laws
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... Sweden , April 28, 2016 First ... M (139.9), up 966% compared with the first quarter of 2015 ... profit totaled SEK 589.1 M (loss: 18.8) and the operating margin ... 7.12 (loss: 0.32) Cash flow from operations was SEK ... The 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Mass. , June 23, 2016   ... development of novel compounds designed to target cancer ... napabucasin, has been granted Orphan Drug Designation from ... the treatment of gastric cancer, including gastroesophageal junction ... stemness inhibitor designed to inhibit cancer stemness pathways ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network for ... Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is to ... are designed, built and brought to market. , The Design Lab is Supplyframe’s ...
(Date:6/23/2016)... NEWPORT BEACH, Calif. , June 23, 2016 /PRNewswire/ ... offering new biological discoveries to the medical community, has ... and co-founder Matthew Nunez . "We ... provide us with the capital we need to meet ... funding will essentially provide us the runway to complete ...
Breaking Biology Technology: