Navigation Links
Ironing out the link between H. pylori infection and gastric cancer
Date:12/21/2012

H. pylori frequently causes gastric ulcers and is also one of the greatest risk factors for gastric cancer. H. pylori infection is also associated with another gastric cancer risk factor, iron deficiency. In this issue of the Journal of Clinical Investigation, researchers led by Richard Peek at Vanderbilt University investigated the influence of iron on H. pylori-induced gastric cancer. Peek and colleagues found that low iron accelerated the development of H. pylori-associated cancerous lesions in gerbils. Further, H. pylori strains isolated from a human population at high risk for gastric cancer were more virulent and produced greater inflammation if they came from patients with low iron levels. In an accompanying article, El-Omar Emad of Aberdeen University discusses how iron levels could be used to identify patients that are at a higher risk for gastric cancer after H. pylori infection.

TITLE:
Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans

AUTHOR CONTACT:
Richard M. Peek, Jr.
Vanderbilt University School of Medicine, Nashville, TN, USA
Phone: 615-322-5200; Fax: 615-343-6229; E-mail: richard.peek@vanderbilt.edu

View this article at: http://www.jci.org/articles/view/64373?key=95552f8a58ca300dd6bc

ACCOMPANYING ARTICLE

TITLE:
Iron deficiency and H. pylori-induced gastric cancer: too little, too bad

AUTHOR CONTACT:
Emad El-Omar
Aberdeen University, Foresterhill, Aberdeen, , GBR
Phone: +44 (0)1224 437548; E-mail: e.el-omar@abdn.ac.uk

View this article at: http://www.jci.org/articles/view/67200?key=98b2d035a72beb6365c9


'/>"/>

Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Related biology news :

1. The findings between DNMs and autism provides global view of mutability on human diseases
2. New menhaden study will help identify balance between fishing and preserving Bay forage fish
3. Dark Ages scourge enlightens modern struggle between man and microbes
4. Multiple sclerosis immune exchange between brain and blood is uncovered
5. Researchers study links between conflict and fisheries in East Africa
6. Mongolia and the Altai Mountains: Origins of genetic blending between Europeans and Asians
7. Bridging the gap between genomics and education
8. Pigs look healthy but test positive for flu at fairs; transmission seen between pigs and humans
9. New study confirms erroneous link between XMRV and prostate cancer-contamination was the cause
10. UCLA researchers discover missing link between stem cells and immune system
11. Menopause evolved to prevent competition between in-laws
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/10/2016)... BLUE BELL, Pa. , March 10, 2016   ... U.S. Customs and Border Protection (CBP) is testing ... in San Diego to help identify ... United States . The test, designed to help determine ... outdoor, pedestrian environment, began in February and will run until ...
(Date:3/8/2016)... , March 8, 2016   Valencell , ... today announced it has secured $11M in Series ... Tech, a new venture fund being launched by ... participation from existing investors TDF Ventures and WSJ ... to continue its triple-digit growth and accelerate its ...
(Date:3/2/2016)... 2, 2016 ... of the  "Global Biometrics Market in Hospitality ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , Global biometrics market ... a CAGR of around 27%   ... announced the addition of the  "Global Biometrics ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... ... April 27, 2016 , ... A compact PET scanner called ... MRI (Magnetic Resonance Imaging) in existing third-party MRI systems. PET and MRI are ... animal subjects. Simultaneous PET/MRI imaging offers a solution to many challenges that face ...
(Date:4/26/2016)... ... April 27, 2016 , ... Cameron Cushman ... an associate in the firm’s Intellectual Property practice group. , Clients turn to ... applications. He has an electrical engineering and computer engineering background, and experience in ...
(Date:4/26/2016)... ... April 26, 2016 , ... This unique "Fertility Happy ... will offer attendees an opportunity to get the lowdown on female fertility and the ... and appetizers, Dr. Jesse Hade, of Boston IVF - The Arizona Center, will give ...
(Date:4/26/2016)... Seattle, Washington (PRWEB) , ... April 26, 2016 ... ... based non-profit, today announced the opening of its first round of pre-proposal competition ... thinking. The organization seeks to identify ideas with the highest potential to ...
Breaking Biology Technology: