Navigation Links
Iodine may alleviate swelling in retinitis pigmentosa patients' retinas
Date:7/21/2014

Boston Cystoid macular edema (CME) is a common complication of retinitis pigmentosa (RP), a family of retinal diseases in which patients typically lose night and side vision first and then develop impaired central vision. CME can also decrease central vision. Current treatments for CME in RP are not always effective and can lead to adverse results.

Researchers from the Massachusetts Eye and Ear, Harvard Medical School, and Boston University School of Medicine tested whether the extent of retinal swelling due to CME was inversely related to dietary iodine intake in patients with RP and found that it was. This finding raises the possibility that an iodine supplement could help limit or reduce central foveal swelling in RP patients with CME. Their results are presented online in the July issue of JAMA Ophthalmology.

Past research performed on a previous population showed an inverse association between the presence of CME and reported iodine supplementation in RP patients. This finding and physiology research by others pointed to iodine as being worth investigating further. In the present experiment, the researchers performed a cross-sectional observational study of 212 nonsmoking patients 18 to 69 years of age who were referred to Mass. Eye and Ear for RP with visual acuity of no worse than 20/200 in at least one eye. They used optical coherence tomography to measure central foveal swelling due to CME in the patients. Total dietary intake of iodine was estimated from multiple (preferably, 10) spot urine samples collected at home.

The investigators found that the magnitude of central foveal swelling due to CME was inversely related to urinary iodine concentration when emphasizing data with more reproducible urinary iodine concentrations (p<.001) -- patients with the lowest urinary iodine levels tended to have retinas with the most swelling.

"Additional study is required to determine whether an iodine supplement can limit or reduce the extent of CME in patients with RP," said Michael A. Sandberg, Ph.D., lead author of the study and senior scientist in the Berman-Gund Laboratory for the Study of Retinal Degenerations at Massachusetts Eye and Ear and Associate Professor of Ophthalmology at Harvard Medical School.


'/>"/>

Contact: Mary Leach
Mary_Leach@meei.harvard.edu
Massachusetts Eye and Ear Infirmary
Source:Eurekalert

Related biology news :

1. Drug shown to reverse radioiodine resistance in some advanced thyroid cancers
2. Study associates excess maternal iodine supplementation with congenital hypothyroidism in newborns
3. New study associates excess maternal iodine supplementation with congenital hypothyroidism
4. Dartmouth scientists track radioactive iodine from Japan nuclear reactor meltdown
5. Compound Formula Rehmannia alleviates dyskinesia in Parkinsons disease
6. Sericin can alleviate diabetic hippocampal injury
7. Olive oil component alleviates intestinal ischemia and reperfusion
8. The potential of psilocybin to alleviate psychological distress in cancer patients is revealed
9. Alzheimers disease in mice alleviated promising therapeutic approach for humans
10. Making a mental match: Pairing a mechanical device with stroke patients
11. Immune function predicts infection risk among child trauma patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
(Date:4/4/2017)... 2017   EyeLock LLC , a leader of ... States Patent and Trademark Office (USPTO) has issued U.S. ... of an iris image with a face image acquired ... company,s 45 th issued patent. ... given the multi-modal biometric capabilities that have recently come ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... San Diego-based team building and ... rebranding initiative announced today. The bold new look is part of a transformation ... moves into a significant growth period. , It will also expand its service offering ...
(Date:10/10/2017)... -- International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... market and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase ... "The residential security market has experienced continued growth, ...
(Date:10/9/2017)... Oct. 9, 2017  BioTech Holdings announced today ... which its ProCell stem cell therapy prevents limb ... The Company, demonstrated that treatment with ProCell resulted ... saved as compared to standard bone marrow stem ... resulted in reduction of therapeutic effect.  ...
(Date:10/9/2017)... Texas (PRWEB) , ... October ... ... study published on October 5, 2017, in the medical journal, Epilepsia, Brain ... with the gold standard, video EEG, in detecting generalized tonic-clonic seizures (GTCS) ...
Breaking Biology Technology: