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Investigating the role of aging and poor nutrition on colon cancer: NIH awards Einstein $3.2 million grant
Date:5/8/2014

May 8, 2014 (BRONX, NY) Two risk factors getting older and eating poorly are implicated in more than 80 percent of colon cancer cases in developed countries. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have received a $3.2 million grant from the National Institutes of Health (NIH) to investigate how aging and poor nutrition interact to cause the mutations responsible for driving colon cancer development.

Colon cancer is the second leading cause of cancer-related deaths in the United States (behind lung cancer) and the third most common cause of cancer in men and women. According to the Centers for Disease Control and Prevention, more than 130,000 people are diagnosed with the disease each year and more than 50,000 men and women will die from it. The vast majority of these cancers occur in people 50 or older.

"We know that age is a major risk factor for all types of cancer, and we also understand that lifelong dietary habits play an extremely important role in the development of colorectal cancers," said Leonard Augenlicht, Ph.D., professor of medicine and of cell biology at Einstein, director of the Biology of Colon Cancer Program at the NCI-designated Albert Einstein Cancer Center, and principal investigator on the grant.

Dr. Augenlicht has used mouse models to replicate how a Western-style diet affects the colon. Such diets are high
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Contact: Deirdre Branley
Deirdre.Branley@einstein.yu.edu
718-430-8806
Albert Einstein College of Medicine
Source:Eurekalert

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