Navigation Links
Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy
Date:12/23/2010

a lot of the heating that your body might [otherwise] experience," said Kachur.

The theory goes that the amount of infrared light can be varied to control the amount of drug that is released from the gold-coated liposomes.

"By using more or less light, you can release more or less of the drug and time the responses as well, so when you trigger light, some drug will leak, you can trigger it again and have more drug leak, or you can wait a little while, let the drug disperse, do its thing, then trigger it again. It allows for a lot more freedom with the release process," said Leung. "By having this very triggered response you can hit that therapeutic window."

Despite increased blood-flow to tumor cells and the key-in-lock action of the ligands, some liposomes may still end up inside healthy cells. In that case, the gold-coating could potentially act to prevent release of the toxic drug to the healthy cells.

By selectively shining the infrared light only in the tumor region, doctors could make sure only liposomes in the tumor region are able to release the drug.

"Once you know where the tumors are, you can go ahead and point your light source toward those areas. Whatever else is left will leave the body or may be slowly released, but not to as high or as toxic of levels as it would be if you just injected the drug systemically," said Leung.

The invention has another bonus: "The gold-coated liposome is biodegradable, which is one of the best parts of our system," said Leung. Currently there are no approved chemotherapeutic treatments that allow the gold nanostructures to be eliminated from the body by the body's own mechanisms, said Leung.

Kidneys, the organs that normally filter waste molecules out of the blood, have a limit as to the size of molecule they can filter. "Because of the size it degrades into, our system should be clearable via the kidney, which is really unique," said Leung.

There st
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. UGA licenses invention that kills food-borne pathogens in minutes
2. Tel Aviv University invention busts dust
3. New invention could improve treatment for children with water on the brain
4. Invention helps students learn surgical techniques before operating on patients
5. Vitiligo skin disorder could yield clues in fight against melanoma
6. Saliva proteins could help detection of oral cancer
7. Research about plant viruses could lead to new ways to improve crop yields
8. Nanodiamond drug device could transform cancer treatment
9. UNC study on properties of carbon nanotubes, water could have wide-ranging implications
10. So-called sandfish could help materials handling and process technology specialists
11. Discovery of natural compounds that could slow blood vessel growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy
(Date:9/18/2014)... across racial and ethnic groups describe losing eyesight ... day-to-day life, more so than other conditions including: ... of African-Americans, 49% of non-Hispanic whites, 43% of ... disease or ailment is the worst that could ... followed by AIDS/HIV. Hispanics and Asians ranked ...
(Date:9/18/2014)... world-leading provider of scientific, technical and medical information ... Society (ARMS), recognized the academic research achievements of ... Researcher of the Year Awards. , The award ... Centre and in conjunction with the ARMS 2014 ... and New Zealand,s scientific community. Guest of honour ...
(Date:9/18/2014)... in the protective tentacles of host anemones, but new ... of kilometres across the open ocean. Although the process ... this is the first time that the high level ... , Dr Steve Simpson, Senior Lecturer in Marine Biology ... colleagues from the Australian Research Council Centre of Excellence ...
Breaking Biology News(10 mins):Americans rate losing eyesight as having greatest impact on their lives 2Americans rate losing eyesight as having greatest impact on their lives 3Elsevier and Australasian Research Management Society award scientists at Scopus ceremony 2Expedition finds Nemo can travel great distances to connect populations 2Expedition finds Nemo can travel great distances to connect populations 3
... Astronauts are known to have a higher risk of getting ... with weightlessness, confined crew quarters, being away from family and ... not getting enough sleep - are known to wreak havoc ... immunobiologist Ty Lebsack at the University of Arizona has discovered ...
... 2010 Scientists studying the environmental impact of Hurricane ... city of New Orleans have revealed the ecological impact ... The findings, published in a special issue of ... caused significant ecological damage by altering coastal chemistry and ...
... to ionizing radiation can result in mutations or other ... a new study led by researchers with the U.S. ... has revealed another way in which radiation can promote ... the researchers discovered that radiation exposure can alter the ...
Cached Biology News:Immune system compromised during spaceflight, study finds 2Immune system compromised during spaceflight, study finds 3New research reveals Hurricane Katrina's impact on ecological and human health 2New research reveals Hurricane Katrina's impact on ecological and human health 3Study raises new concerns about radiation and breast cancer 2Study raises new concerns about radiation and breast cancer 3
(Date:9/19/2014)... 19, 2014 BioTech News Coverage: ... and results of studies and trials.  Companies in focus ... (NYSE: LLY ), Gilead Sciences Inc. (NASDAQ: ... CELG ) and Arena Pharmaceuticals Inc. (NASDAQ: ARNA) ... prodrug therapeutics for the treatment of cancer, announced that ...
(Date:9/19/2014)... -- , The first grants awarded to ... (ESPE) Meeting  Investment supports innovative projects for ... field of growth  , EMD Serono, a ... , today announced the first recipients of the Grant ... announced during a Satellite Symposium organized by EMD Serono ...
(Date:9/18/2014)... 2014 About POCT ... a clinical laboratory. It helps in making fast ... and medication. POCT is gaining popularity due to ... such as diabetes, heart disease, and obesity. It ... standardized to minimize errors during the diagnosis of ...
(Date:9/18/2014)... , September 18, 2014 ... ( http://www.researchandmarkets.com/research/czvg3s/biocompatible ) has announced the ... - Global Strategic Business Report" ... http://photos.prnewswire.com/prnh/20130307/600769) ,This report analyzes the worldwide ... Million by the following Product Segments: ...
Breaking Biology Technology:Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3POCT Market in China 2014-2018 2Biocompatible Materials - Global Strategic Business Report 2014 2Biocompatible Materials - Global Strategic Business Report 2014 3
... Wisconsin Institute for Discovery It was inevitable that ... interdisciplinary research center on the UW-Madison campus would be ... a $3 billion, 10-year initiative to fund human embryonic ... research is a sizable part of what will happen ...
... House of Representatives has passed a bill that allows ... will be used against them in a patent dispute. ... institutions could count as prior art, said Andy Cohn, ... , ,This could invalidate a patent claim though ...
... this, I am sitting with an angry Mediterranean Sea roaring ... smart Israeli start-ups as the first winter storm hits Tel ... Europe and Israel, taking an assessment of the technology markets ... , ,What strikes me on this visit is the presumed ...
Cached Biology Technology:Doyles proposal is about more than keeping pace with California 2Doyles proposal is about more than keeping pace with California 3Innovation thrives in Europe 2Innovation thrives in Europe 3
... Cellject Uno Electroporator is a simple, ... optimum efficiencies in bacterial and yeast ... one of two voltages and either ... mm cuvettes. On pressing the pulse ...
Request Info...
Maxi XL Hybridization Oven for Extra Large bottles. 6 bottle (70 mm) rotisserie + shaker tray available for simultaneous use. Includes linear and orbital shaker trays, 4 extra large bottles, pack o...
Shake 'n' Stack oven - New Model (includes 10 bottle capacity rotisserie, adjustable feet, drip tray, manual)...
Biology Products: