Navigation Links
Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy
Date:12/23/2010

a lot of the heating that your body might [otherwise] experience," said Kachur.

The theory goes that the amount of infrared light can be varied to control the amount of drug that is released from the gold-coated liposomes.

"By using more or less light, you can release more or less of the drug and time the responses as well, so when you trigger light, some drug will leak, you can trigger it again and have more drug leak, or you can wait a little while, let the drug disperse, do its thing, then trigger it again. It allows for a lot more freedom with the release process," said Leung. "By having this very triggered response you can hit that therapeutic window."

Despite increased blood-flow to tumor cells and the key-in-lock action of the ligands, some liposomes may still end up inside healthy cells. In that case, the gold-coating could potentially act to prevent release of the toxic drug to the healthy cells.

By selectively shining the infrared light only in the tumor region, doctors could make sure only liposomes in the tumor region are able to release the drug.

"Once you know where the tumors are, you can go ahead and point your light source toward those areas. Whatever else is left will leave the body or may be slowly released, but not to as high or as toxic of levels as it would be if you just injected the drug systemically," said Leung.

The invention has another bonus: "The gold-coated liposome is biodegradable, which is one of the best parts of our system," said Leung. Currently there are no approved chemotherapeutic treatments that allow the gold nanostructures to be eliminated from the body by the body's own mechanisms, said Leung.

Kidneys, the organs that normally filter waste molecules out of the blood, have a limit as to the size of molecule they can filter. "Because of the size it degrades into, our system should be clearable via the kidney, which is really unique," said Leung.

There st
'/>"/>

Contact: Daniel Stolte
stolte@email.arizona.edu
520-626-4402
University of Arizona
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. UGA licenses invention that kills food-borne pathogens in minutes
2. Tel Aviv University invention busts dust
3. New invention could improve treatment for children with water on the brain
4. Invention helps students learn surgical techniques before operating on patients
5. Vitiligo skin disorder could yield clues in fight against melanoma
6. Saliva proteins could help detection of oral cancer
7. Research about plant viruses could lead to new ways to improve crop yields
8. Nanodiamond drug device could transform cancer treatment
9. UNC study on properties of carbon nanotubes, water could have wide-ranging implications
10. So-called sandfish could help materials handling and process technology specialists
11. Discovery of natural compounds that could slow blood vessel growth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Invention could improve cancer drug delivery, lessen harmful effects of chemotherapy
(Date:7/11/2014)... 11, 2014 Research and Markets ... Technology Market - Industry Analysis Size Share Growth Trends ... http://photos.prnewswire.com/prnh/20130307/600769 ... created a need for high level security in both ... authentication such as username and passwords, tokens etc. are ...
(Date:7/11/2014)... Brazil- In the brains of all vertebrates, information ... an electric or chemical signal to be passed ... which are the most abundant type of synapse, ... is crucial for learning, memory, perception and cognition, ... critical for brain function. For instance, every ...
(Date:7/10/2014)... , June 27, 2014  The American ... National Institute of Standards and Technology (NIST) and ... its academic research and forensic science expert members ... Board is an element of the NIST,s Organization ... are among the first appointments made to the ...
Breaking Biology News(10 mins):International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2Blame it on the astrocytes 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3
... Feb. 13, 2013 AFCEA,s twelfth annual Homeland ... the Nation Safe", will be hosted at the ... , February 26-28, 2013.  Attendees include government and ... operations, policy and procurement. Additionally, the Conference will ...
... of seven well-studied ant species are opening up ... look at molecular mechanisms that underlie the complex ... Florida carpenter ant, Camponotus floridanus, has revealed a ... how the expression or suppression of particular genes ...
... shows that busy beavers are helping Canada geese get an earlier ... Ponds in Alberta where beavers were active tended to result in ... at reproductive success, according to the study, published recently in ... beavers to early season nesting habits of Canada geese in a ...
Cached Biology News:AFCEA's Homeland Security Conference Returns To Washington, D.C. 2Epigenetics shapes fate of brain vs. brawn castes in carpenter ants 2Epigenetics shapes fate of brain vs. brawn castes in carpenter ants 3Epigenetics shapes fate of brain vs. brawn castes in carpenter ants 4
(Date:7/10/2014)... 10, 2014 Women in the ... to an additional family planning option. Sayana® Press ... at all levels of the health system and ... a widely used contraceptive—Pfizer’s Depo-Provera® (depot medroxyprogesterone acetate)—with ... is the first of four African countries expected ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Unraveling life’s ... together. The Archer Family purchased a DNA ... DNA, but ended up with a lifetime of memories, ... within the family members’ DNA genuinely brought the family ... to search deeper into genetic history and prior to ...
(Date:7/10/2014)... , July 10, 2014  Franciscan St. ... of capnography for respiratory monitoring outside the ... healthcare leaders in embracing state-of-the-art patient safety ... patients are breathing and can alert medical ... measuring the amount of carbon dioxide the ...
(Date:7/10/2014)... --  Ceres, Inc . (Nasdaq: CERE ), ... results for the three months ended May 31, 2014 ... Ceres reported that the company and its customers have ... in Brazil, which concluded in June, despite dry and ... for part of the growing season. Yields of several ...
Breaking Biology Technology:Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9
... 24 Nektar Therapeutics,(Nasdaq: NKTR ) ... quarter and,year ended December 31, 2008. , ... for Nektar," said Howard W. Robin,President and Chief ... polymer,conjugation chemistry platform, we advanced numerous proprietary drug,candidates ...
... European Commission has granted,marketing authorisation for Servier,s Valdoxan(R) ... of adult patients,with major depressive episodes. , ... for improved therapies to treat the,devastating effects of ... Kingdom. "Valdoxan is an innovative, new approach to,the ...
... Gene Network Sciences, Inc. (GNS) today announced that it ... Officer of Stromedix, Inc. and former Executive Vice President ... Directors. Dr. Gilman has been Founder and Chief ... was previously Executive Vice President, Research at Biogen Idec. ...
Cached Biology Technology:Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 2Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 3Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 4Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 5Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 6Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 7Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 8Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 9Valdoxan(R) Granted Marketing Authorisation for the Treatment of Major Depressive Episodes in Europe 2Valdoxan(R) Granted Marketing Authorisation for the Treatment of Major Depressive Episodes in Europe 3Gene Network Sciences Announces Michael Gilman as Board Member 2
Request Info...
... DNA preparations are prepared from customers ... 1mg to multi-gram scales. Each preparation ... and glycerol stocks are maintained to ... selection (Clonal selection includes screening colonies ...
... preparations are prepared from customers high-copy ... to multi-gram scales. Small-scale (1-100mg) ... are made according to customer specifications. ... to customer needs, and glycerol stocks ...
... for automated gigaseal patch clamping. The ... ion channels, such as hERG and ligand-gated ... four pipette heads afford more efficient assays ... discovery. The glass-coated tunnels of the ...
Biology Products: