Navigation Links
Intriguing viral link to intestinal cancer in mice

More than 50% of adults in the United States test positive for human cytomegalovirus (HCMV) infection. For most people, infection produces no symptoms and results in the virus persisting in the body for a long time. HCMV infects many cell types in the body including the cells that line the intestines (IECs). New research, led by Sergio Lira, at Mount Sinai School of Medicine, New York, shows that mice engineered to express the HCMV protein US28 in IECs develop intestinal tumors as they age. These mice also develop more tumors than normal mice in a model of inflammation-induced intestinal tumors. The authors therefore suggest that it is possible that HCMV infection could help promote intestinal cancer in humans, although they caution that much more work is needed if such an association is to be confirmed.


Contact: Karen Honey
Journal of Clinical Investigation

Page: 1

Related biology news :

1. Twins are intriguing research subjects for Notre Dame biometircs researchers
2. Texas Tech researcher: Bee colony collapse associated with viral, fungal infection
3. RD114 envelope proteins provide an effective and versatile approach to pseudotype lentiviral vectors
4. Exciting new avenues of research and policy drive expansion of HIV treatment access, use of antiretrovirals to prevent infections and pursuit of a cure
5. Scientists discover ancient viral invasion that shaped human genome
6. Viral life cycle of malignant catarrhal fever explained
7. Development of new anti-cancer gene therapy approach using lentiviral vectors
8. Iowa State, Ames Lab chemists discover how antiviral drugs bind to and block flu virus
9. Statement of ESHRE on the European Commission proposal of viral screening
10. Triple-combo drug shows promise against antiviral-resistant H1N1, UAB researcher says
11. Study characterizes eczema patients most at risk for dangerous viral infections
Post Your Comments:
(Date:6/22/2016)... Md. , June 22, 2016  The American College ... Trade Show Executive Magazine as one of the ... on May 25-27 at the Bellagio in Las ... on the highest percentage of growth in each of the ... of exhibiting companies and number of attendees. The 2015 ACMG ...
(Date:6/22/2016)... WASHINGTON , June 22, 2016 On ... highly-anticipated call to industry to share solutions for the ... by U.S. Customs and Border Protection (CBP), explains that ... nationals are departing the United States ... criminals, and to defeat imposters. Logo - ...
(Date:6/20/2016)... June 20, 2016 Securus Technologies, a ... solutions for public safety, investigation, corrections and monitoring ... involved, it has secured the final acceptance by ... for Managed Access Systems (MAS) installed. Furthermore, Securus ... to be installed by October, 2016. MAS distinguishes ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 27, 2016  Liquid Biotech USA ... of a Sponsored Research Agreement with The University ... (CTCs) from cancer patients.  The funding will be ... correlate with clinical outcomes in cancer patients undergoing ... then be employed to support the design of ...
(Date:6/24/2016)... ... , ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension ... are higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... bottom of the cuvette holder. , FireflySci has developed several Agilent flow cell ...
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... ... 2016 , ... Charm Sciences, Inc. is pleased to announce ... Research Institute approval 061601. , “This is another AOAC-RI approval of the Peel ... President of Regulatory and Industrial Affairs. “The Peel Plate methods perform comparably to ...
Breaking Biology Technology: