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Intestine crucial to function of immune cells, research shows
Date:12/12/2011

ltiple sclerosis, in which immune cells attack and eventually destroy healthy tissue.

But the next step, said Prof. Gommerman, is to look at human samples for the same type of multi-potentiality they saw in rodent plasma cells that acquired their anti-microbial properties in the gut.

"We're really at the early stages of understanding what we call the microbiome in the gut," said Prof. Gommerman. "There is a role for plasma cells in many autoimmune diseases, and B cells can do a lot more than just make antibodies. We need to understand the full spectrum of their effects within the immune response."


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Contact: Jim Oldfield
jim.oldfield@utoronto.ca
416-946-8423
University of Toronto
Source:Eurekalert

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