Navigation Links
International team discovers likely basis of birth defect causing premature skull closure in infants
Date:11/18/2012

ngs were replicated in another population of 172 cases of children with the condition and 548 unrelated controls. The extensive international collaboration came about because of the desire to include as many cases as possible worldwide to strengthen the findings.

"No matter how we analyzed the data ― whether we included familial cases, cases with other minor anomalies, or mixed children of different ethnic groups together, these two genetic factors were highly significant," said Boyadjiev. "This provides strong evidence that non-syndromic sagittal craniosynostosis has a major genetic component and identifies where the problem is likely to originate."

Boyadjiev added that the genetic differences do not fully explain the development of the condition and that other genes and environmental factors are also likely important. He likened the condition to spina bifida: Infants who develop this defect in their spine are known to have a genetic propensity, but vitamin supplementation with folic acid of pregnant women can prevent many cases. He plans to extend the research to find the exact disease-causing genetic variants and to study other types of craniosynostosis in various ethnic groups. Boyadjiev also will search for a marker in the blood of expectant mothers to identify fetuses at risk for craniosynostosis, which one day may lead to an intervention during pregnancy to prevent craniosynostosis.

"The identification of two biologically plausible candidate genes affecting susceptibility to non-syndromic sagittal craniosynostosis provides promising leads in the search for understanding how these conditions develop," said Emily Harris, chief of the translational genomics research branch at the National Institutes of Health's Institute of Dental and Craniofacial Research.


'/>"/>

Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. UH Case Medical Center leads international study
2. Novetta Solutions Acquires International Biometric Group, LLC
3. International Life Sciences Conferences Address Advancements in High-Content Analysis, Sample Preparation, Clinical Trial Supply and Protein and Antibody Engineering
4. Maya Angelou Center Brings International Women’s Health Summit to Winston-Salem, NC
5. UA engineering professor Shane Snyder to speak in Korea on international water quality
6. Jeff Crandall Honored With SAE International Arnold W. Siegel International Transportation Safety Award
7. 2016 International Congress of Entomology to be held in Orlando, Florida
8. Brazil joins international marine research effort
9. Iconic Darwin finch genome sequenced in Genome 10K international collaboration
10. International regulation curbs illegal trade of caviar
11. The International Society for Advancement of Cytometry presented its 2012 awards at CYTO 2012
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... June 27, 2014  Pomerantz LLP has filed ... ("Provectus" or the "Company")(NYSE-MKT: PVCT) and certain of ... States District Court, Middle District of ... of a class consisting of all persons or ... between December 17, 2013 and May 22, 2014, ...
(Date:7/10/2014)... SPRINGS, Florida , July 1, 2014 ... wallets pave way for convenience and improved security: NXT-ID, Inc. ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... and MasterCard Corporation (NYSE: MA) NXT-ID, Inc., (OTCQB: NXTD) ... is pleased to announce that the second series of 30 ...
(Date:7/10/2014)... COMMACK, N.Y. , July 2, 2014 ... Inc. (ABD) to announce the appointment of the world-renowned ... its Board of Directors. Dr. Ginsburg, with ... two facilities: NY Presbyterian Hospital and Good Samaritan Regional ... Breathing Pacemaker since the late 1980,s and is considered ...
Breaking Biology News(10 mins):SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 2Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 3Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 4Advantages for Digital Wallets Eliminate Need to Carry Credit Cards - Large Scale CNBC Ad Campaign for Latest Smart Wallet to Commence July 7th 5Avery Biomedical Devices, Inc. announces the appointment of Mark E Ginsburg, M.D. to its Board of Directors 2
... time in wild marine fish populations, new research has shown., ... Institute of Marine Science published today in the academic journal ... in the coral trout, a species found on the Great ... the ozone layer., This is the first time skin cancer ...
... While the flower may attract the bee and the admiring ... of life below ground where the action is. The microbial ... niches immediately surrounding and inside a plant,s rootfacilitates the shuttling ... within the soil matrix. This commerce, by enabling the ...
... in the 2012 Olympics might assume their championship performance ... a new study disproves the classic scientific view that ... The study by biomechanics researchers Matthew W. Bundle at ... Southern Methodist University, Dallas, demonstrates that metabolic economy is ...
Cached Biology News:Skin cancer identified for the first time in wild fish populations 2Getting to the root -- unearthing the plant-microbe quid pro quo 2Getting to the root -- unearthing the plant-microbe quid pro quo 3Getting to the root -- unearthing the plant-microbe quid pro quo 4Getting to the root -- unearthing the plant-microbe quid pro quo 5New study: Running mechanics, not metabolism, are the key to performance for elite sprinters 2New study: Running mechanics, not metabolism, are the key to performance for elite sprinters 3
(Date:7/11/2014)... , July 11, 2014  Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
(Date:7/10/2014)... July 10, 2014 Product and ... very low abundance and are often “lost in ... time-consuming. , Join presenters Dr. Rowel Tobias, Senior ... John Anders, Head of Quality at Nanotherapeutics, Inc., ... that can speed detection and quantitation while achieving ...
(Date:7/10/2014)... Mass. (PRWEB) July 10, 2014 Terascala, ... today announced that Alan Swahn, a former vice president ... executive team as vice president of marketing. Terascala’s software ... Dell and NetApp create the highest performance and most ... been appointed to guide Terascala’s channel expansion and broaden ...
(Date:7/10/2014)... OMICS Group’s 5th International conference and exhibition ... at Double Tree by Hilton Beijing, China is all ... & Bioanalytical research methods only to facilitate improved living ... Dr. Srinubabu Gedela, MD of OMICS Group Inc has ... one in bringing a unique and international mix of ...
Breaking Biology Technology:Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4
... one company is earning their bread and cheese with ... , a global satellite communications provider, has deployed a ... satellite-based broadband access provider. , ,IsoTropic operates an integrated ... 21 acres in rural Wisconsin, and it maintains a ...
... Technologies Inc. , a provider of medical imaging devices and ... has received a notice from the staff of the ... to delisting after missing another opportunity to file financial reports. ... the quarter ended June 30 would serve as an additional ...
... Wis. - A new biofuels company spun out of ... also be presented with the second of two state grants. ... of biofuels, will receive a $115,000 grant as part of the ... . Doyle was on hand to announce the grant, which is ...
Cached Biology Technology:Rural company works to improve broadband 2Madison business receives $115,000 of new state biofuels funding 2
Microlite 1+ 1x12 Strip assembled, flat bottom; the ideal vessel for low signal luminescent reactions, offering medium binding with enhanced dynamic range, extra high reflectivity and minimal cross t...
Immulon 4 HBX 1x12 Strip, flat bottom; high binding extra surface with special resin and irradiation, offers maximum protein uptake....
... 0-10 psi precision pressure regulator and pressurized syringe ... Faster liquid-switching Steady flow rate Microinjecting ... Can be added to any new ... any third-party manufacturer, even homemade. Connect to house ...
...
Biology Products: