Navigation Links
International space station plays host to innovative infectious disease research
Date:2/18/2013

ers to replicate aspects of cell culture in the spaceflight environment.

Back at ASU, RWV reactor experiments were conducted by Nickerson and her team to help confirm that Hfq plays a central regulatory role in the Salmonella response to spaceflight conditions. Nickerson has also used this RWV technology to grow three dimensional (3-D) cell culture models that mimic key aspects of the structure and function of tissues in the body. These 3-D models are being used in the Nickerson lab as human surrogates to provide novel insight into the infectious disease process not obtainable by conventional approaches and for drug/therapeutic testing and development for treatment and prevention.

Nickerson also focuses research efforts on determining the entire repertoire of environmental factors that may influence bacterial response to spaceflight culture. For example, she found that the ion concentration in the cell culture media played a key role in the resulting effect of spaceflight on Salmonella virulence. Using the RWV, she was able to identify specific salts that may be responsible for this effect.

Nickerson's long list of firsts (first study to examine the effect of spaceflight on the virulence of a pathogen, first to obtain the entire gene expression response of a bacterium to spaceflight, first to profile the infection process in human cells in spaceflight, first identification of a spaceflight-responsive global gene regulator acting across bacterial species), will soon be augmented with a new experiment, that will be flown on SpaceX Dragon slated for the ISS later this year. Nicknamed PHOENIX, the project will mark the first time a whole, living organismin this case a nematodewill be infected with a pathogen and simultaneously monitored in real time during the infection process under microgravity conditions.

This and future studies aboard ISS will almost certainly deepen science's understanding of the molecular and cellular cues
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert

0

GOOD

Page: 1 2 3 4 5 6

Related biology news :

1. Maris presentation tops ANZFSS International Symposium
2. International biodiversity data symposium to mark the kickoff of the EU BON project
3. AERA announces publication of the International Handbook of Research on Environmental Education
4. Conference Programme Committees selected for the 20th International AIDS Conference (AIDS 2014)
5. Winners of 10th annual International Science & Technology Visualization Challenge announced
6. The 2013 International Conference on Genomics in Europe will take place in Ghent, Belgium
7. Flashback Data Remains Only Non-Governmental Digital Forensics Lab with ASCLD/LAB International Accreditation
8. International study: Where theres smoke or smog, theres climate change
9. Biophysical Society announces winners of 2013 international travel awards
10. International study suggests human genes influence gut microbial composition
11. U of M to lead international virtual institute studying climatic and human effects on Earth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... a class of pharmaceuticals can both prevent and treat ... as "TSPO ligands," are currently used for certain types ... TSPO ligand in young adult mice when pathology was ... pathology was quite severe," said lead researcher Christian Pike ... reduced measures of pathology and improved behavior at both ...
(Date:5/21/2013)... Mo. Cancers of all types become most deadly ... Once cancer has reached this stage, it becomes very ... tumors that can develop. Now, researchers at the University ... nanoparticles that target lymphoma tumor cells wherever they may ... of oncology in the MU College of Veterinary Medicine, ...
(Date:5/21/2013)... stores, phosphatidylserine is a natural food supplement produced ... cognition and slow memory loss, it,s a popular ... a team headed by Prof. Gil Ast and ... of Human Molecular Genetics have discovered ... genes involved in degenerative brain disorders, including Parkinson,s ...
Breaking Biology News(10 mins):Drugs found to both prevent and treat Alzheimer's disease in mice 2MU researchers develop radioactive nanoparticles that target cancer cells 2Common food supplement fights degenerative brain disorders 2
... iris recognition and DNA databases, but researchers in India ... allow law enforcement agencies and airport security to recognize ... gait. The team reveals details of a comprehensive framework ... of the Inderscience publication, the International Journal of ...
... same time impact the delivery of drugs and explain ... synthetic nanoparticles that can penetrate a cell without poking ... The key to their approach? Stripes. The ... of two different kinds of molecules can quickly pass ...
... The appointment of James Watson as Director ... an explosive development of research at Cold Spring Harbor ... of investigators with diverse scientific interests. In a ... scientists involved tell the stories of research carried out ...
Cached Biology News:Tell me by the way I walk 2MIT: Stripes key to nanoparticle drug delivery 2Watson-inspired innovation in research at Cold Spring Harbor Laboratory 2
(Date:5/21/2013)... Through science fairs, workshops, kits for building optical ... organizations will continue their work to increase awareness about ... daily life with the aid of SPIE Education ... countries, are the first of two groups of recipients ... international society for optics and photonics , in 2013. ...
(Date:5/21/2013)... Raleigh, NC (PRWEB) May 21, 2013 ... and financial services company for clinical trials, announced ... Aggregate Spend Solutions, LLC. Clinverse’s ClinPay® FLS ... automated investigator payment process. SpendMD ™, ... only complete solution for tracking and reporting transfer ...
(Date:5/21/2013)... (PRWEB) May 21, 2013 Emerson ... announced that Dr. Charles Signorino, the Company’s Chief Executive ... 1, 2013 after 32 years of service. As part ... Emerson’s current President, has been named as Dr. Signorino’s ... in the pharmaceutical industry, having made a significant contribution ...
(Date:5/21/2013)... MN (PRWEB) May 21, 2013 Revolutionary ... patented automatic colony counter, announced today that they have ... products , the IncuCount, IntelliCount, InCount and ImpressCount. ... and sophistication are especially useful in food microbiology and ... given an updated look. A bright white enclosure ...
Breaking Biology Technology:Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 2Learning About Light: Education Outreach Projects Funded in 10 Countries Through First Round of SPIE Grants 3Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3Emerson Resources Announces CEO Retirement and Appointment of Successor 2Emerson Resources Announces CEO Retirement and Appointment of Successor 3Revolutionary Science Announces New Automatic and Manual Colony Counting Products 2
... New research suggests that some patients develop a potentially ... bacterial cells in their bodies have gene mutations that ... with implants can develop infections because of a biofilm ... devices. Researchers found that some strains of the bacteria, ...
... electronic and mechanical effects occurring in devices and ... are being investigated by researchers around the world. ... the generation of light, optical sensing, and information ... in physics and applications in this area, the ...
... (Nasdaq: CELG: $68) has been picked by S&P Capital ... carries S&P Capital IQ,s highest investment recommendation of 5-STARS, ... be among the best positioned biotechs for long-term growth, ... Equity Analyst at S&P Capital IQ.  "We believe the ...
Cached Biology Technology:Study offers clues as to why some patients get infections from cardiac implants 2Study offers clues as to why some patients get infections from cardiac implants 3Study offers clues as to why some patients get infections from cardiac implants 4Study offers clues as to why some patients get infections from cardiac implants 5Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 2Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 3Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 4Optics Express Focus Issue: Collective phenomena in photonic, plasmonic and hybrid structures 5S&P Capital IQ Picks Celgene Focus Stock of the Week 2S&P Capital IQ Picks Celgene Focus Stock of the Week 3
Rabbit polyclonal to FANCG ( Abpromise for all tested applications). Antigen: Synthetic peptide: MSRQTTSVGSSC, corresponding to amino acids 1 - 12 of Human FANCG. Entrez GeneID: 2189 Swis...
Rabbit polyclonal to DcR2 ( Abpromise for all tested applications). entrezGeneID: 8793 SwissProtID: Q9UBN6...
...
...
Biology Products: