Navigation Links
International space station plays host to innovative infectious disease research
Date:2/18/2013

rial behavior made use of microarray technology, which allows analysis of gene expression for the entire 4.8 million base pairs found in Salmonella's circular chromosome. Data revealed that 167 distinct genes and 73 proteins had been altered during growth under microgravity conditions, including (but not limited to) virulence-associated genes. Of the 167 genes undergoing up- or down-regulation in response to spaceflight, one third were under the control of the Hfq master regulator protein.

These microgravity studies open a new window into the infectious disease mechanisms of Salmonella, an aggressive pathogen responsible for infecting an estimated 94 million people globally and causing 155,000 deaths annually. In the U.S. alone, more than 40,000 cases of Salmonellosis are reported annually, resulting in at least 500 deaths, and health care costs in excess of $50 million. However, only a small percentage of infections with Salmonella are reported, and the estimated two to four million cases of Salmonella-induced gastroenteritis which occur in the United States each year constitute a significant economic loss of productive work time, reported to exceed $2 billion annually.

While Salmonella has been a pathogen of choice for a broad range of spaceflight investigations, Nickerson stresses that her findings have spaceflight and Earth-based implications. Her confidence is based on her team's work showing that microgravity culture also uniquely alters gene expression and pathogenesis-related responses in other microorganisms.

Nickerson emphasizes that the ISS provides an unprecedented opportunity to study the infection process under microgravity conditions, enabling advances in our understanding of microbial gene expression and accompanying host responses during infection in fine-grained detail. This novel approach holds the potential to identify new classes of genes and proteins associated with infection and disease not possible using traditio
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert

Page: 1 2 3 4 5 6

Related biology news :

1. Maris presentation tops ANZFSS International Symposium
2. International biodiversity data symposium to mark the kickoff of the EU BON project
3. AERA announces publication of the International Handbook of Research on Environmental Education
4. Conference Programme Committees selected for the 20th International AIDS Conference (AIDS 2014)
5. Winners of 10th annual International Science & Technology Visualization Challenge announced
6. The 2013 International Conference on Genomics in Europe will take place in Ghent, Belgium
7. Flashback Data Remains Only Non-Governmental Digital Forensics Lab with ASCLD/LAB International Accreditation
8. International study: Where theres smoke or smog, theres climate change
9. Biophysical Society announces winners of 2013 international travel awards
10. International study suggests human genes influence gut microbial composition
11. U of M to lead international virtual institute studying climatic and human effects on Earth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... Canada , April 17, 2015 ... growing security concerns, and technological advancement to drive ... until 2020   According ... Saudi Arabia Biometric Systems Market Forecast &  Opportunities, 2020 ", biometric systems ... is projected to register growth at CAGR of ...
(Date:4/13/2015)... -- higi, a leading cloud-based consumer engagement platform that provides ... their communities around health and wellness, announced today the ... ... convenient vehicle to receive validated health information from consumers. ... API will allow higi,s trusted partners, on a user ...
(Date:4/6/2015)... , Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/143028 for MINIATURE, MULTI-PURPOSE ... TRANSFER  NXT-ID introduces a new revolutionary ... patent surrounds the use of miniature antenna modules ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4
... Calif.) A majority of women with breast cancer today ... their breast tissue. Results of a UC Davis study, however, ... the same breast are treated with a second lumpectomy rather ... number of years those women survive in half. ...
... The most comprehensive geological review ever undertaken of the upper ... and dammed rivers could flood large swaths of wetlands this ... "In terms of sea-level increases and river sediments flowing ... will face conditions they last saw in the Holocene, from ...
... Foundation has granted two Clemson University professors $250,000 to ... 10 times smaller in diameter than a human hair ... both money and time compared to more traditional methods ... work like a sponge to draw up fluids from ...
Cached Biology News:Second lumpectomy for breast cancer reduces survival rates 2Bays on US Gulf Coast vulnerable to flooding 2
(Date:5/1/2015)... 2015 OncoTAb, Inc., a ... company, announced that Pinku Mukherjee, Ph.D. has received the ... of Governors’ highest faculty honor. Mukherjee received the award, ... for her innovative research and development of cancer diagnostics ... a crowning moment in my scientific career,” said Mukherjee, ...
(Date:5/1/2015)... , May 1, 2015 ... Genetic Technologies Ltd (NASDAQ: GENE ), Agilent ... Scientific Inc. (NYSE: TMO ), Sequenom Inc. ... PKI ). Free research report on Genetic ... On Thursday, April 30, 2015, the NASDAQ Composite ...
(Date:4/30/2015)... 2015  Roka Bioscience, Inc. (NASDAQ: ROKA ), ... solutions for the detection of foodborne pathogens, announced plans ... of 2015 on May 7, 2015 after the close ... also host a conference call at 4:30 p.m. Eastern ... quarter financial results. During the conference call, material information ...
(Date:4/30/2015)... 2015 Oxford Finance LLC ("Oxford"), a specialty ... and healthcare services companies, today announced the closing of ... Celula, Inc., a diagnostic testing company focused on improving ... care and improved outcomes.  Proceeds of the loan will ... commercialization of its products in the U.S. and ...
Breaking Biology Technology:OncoTAb CSO Awarded the University of North Carolina’s O. Max Gardner Award 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5Roka Bioscience to Report First Quarter 2015 Financial Results On May 7, 2015 2Oxford Finance Provides $10 Million Debt Financing to Celula 2
... Researchers from IBM (NYSE: IBM ) ... made a nanomedicine breakthrough in which new types ... destroy antibiotic-resistant bacteria and infectious diseases like Methicillin-resistant ... cells unharmed. (Logo:   http://photos.prnewswire.com/prnh/20090416/IBMLOGO ) ...
... NEW YORK and TEL AVIV, Israel, April 4, 2011 ... LLC, and Pronto Diagnostics Ltd, both of which are ... announced that they have entered into a Distribution Agreement ... for Signal,s Myeloma Prognostic Risk Signature (MyPRS) test in ...
... April 4, 2011 Reportlinker.com announces that a ... catalogue: Nanobiotechnologies- applications, markets and ... Nanotechnology is the creation and utilization ... of matter on the nanometer-length scale (a nanometer ...
Cached Biology Technology:IBM and The Institute of Bioengineering and Nanotechnology Find Breakthrough for MRSA Treatment 2IBM and The Institute of Bioengineering and Nanotechnology Find Breakthrough for MRSA Treatment 3IBM and The Institute of Bioengineering and Nanotechnology Find Breakthrough for MRSA Treatment 4Signal Genetics and Pronto Diagnostics Announce Distribution Agreement 2Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 2Reportlinker Adds Nanobiotechnologies - Applications, Markets and Companies 3
Request Info...
... Blunt TOPO PCR Cloning ... designed for cloning and ... PCR products. The pCR4Blunt-TOPO ... Cloning and greater than ...
Recommend to use at 1000X dilutions for cell culture (e.g. Add 1 ul to 1 ml of culture medium.)...
...
Biology Products: