Navigation Links
International research team seeks to unravel flatworm regeneration
Date:7/21/2009

Planarian flatworms are only a few millimeters up to a few centimeters in length, live in freshwater and are the object of intense research, because they possess the extraordinary ability to regenerate lost tissue with the help of their stem cells (neoblasts) and even grow an entirely new worm out of minute amputated body parts. Now researchers from the Max Delbrck Center in Berlin, Germany together with researchers in the US and Canada present the first comprehensive catalogue of small RNAs of planaria, elements that regulate gene expression. They also have identified small RNAs which may play a role in regeneration and stem cell function, Nikolaus Rajewsky from the MDC points out (PNAS, Early Edition)*.

Research suggests that the regeneration of the flatworm involves hundreds of genes. But how are these genes regulated? With the latest technologies researchers search for molecules which regulate genes, such as the small RNAs and especially microRNAs (miRNAs).

Of the hundreds of known planarian species the team of researchers from Germany, the US and Canada chose Schmidtea mediterranea. Full 30 percent of the cells of this species consists of stem cells, making it a unique model system to investigate the function of stem cells.

Many planaria genes resemble those of humans, and also many genes specifically linked to planarian stem cell biology and regeneration are conserved in humans. Understanding planarian regeneration therefore promises to yield important insights into human regeneration and stem cell biology, the researchers are convinced.

The researchers looked for small RNAs in stem cells as well as in the whole planarian organism. They discovered 60 new microRNA genes and could demonstrate that ten microRNAs are specifically linked to stem cell biology and may therefore play a role in regeneration. A few of these microRNAs also exist in humans.

Furthermore, the researchers discovered millions of piRNA
'/>"/>

Contact: Barbara Bachtler
bachtler@mdc-berlin.de
49-309-406-3896
Helmholtz Association of German Research Centres
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
2. Journal of Vascular and Interventional Radiology increases impact, international reach
3. International team of students and scientists on month-long field course in Siberian Arctic
4. ESHRE launches international study of polar body screening
5. International collaboration by scientists culminates in novel ion channels database
6. Susan E. Gardiner receives ASHS Outstanding International Horticulturist Award
7. SRI International announces findings from new upper atmospheric radar system for scientific research
8. International Serious Adverse Events Consortium announces initial study results in its global research collaboration to identify genetic markers related to drug induced liver injury
9. World-class innovation through international cooperation
10. International team tracks clues to HIV
11. SRI International to screen drugs that fight 2009 H1N1 influenza A
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
International research team seeks to unravel flatworm regeneration
(Date:6/16/2015)... , June 16, 2015 Fingerprint ... touch fingerprint sensors in the company,s portfolio from one of ... are planned to mainly take place during the third quarter ... Asia . Jörgen Lantto, CEO ... of    the   growing interest from smartphone OEMs in ...
(Date:6/15/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... commerce market, announces that its leading payment security technology, the ... Experience! @ NYC June 18th. Digital Experience! @ ... in technology to over 300 of the top media covering ... Pavilion in New York City from ...
(Date:6/9/2015)... , June 9, 2015   MedNet Solutions ... the entire spectrum of clinical research, will be providing ... technology platform at the 2015 Drug Information Association (DIA) ... on June 15-17.  These presentations will include previews of ... out in the upcoming iMedNet 2015 Feature ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 3MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 3
... physiologists helped solve physiological problems related to flight, research ... in the air, according to Jay B. Dean, of ... Dr. Dean prepared a presentation on his historical research ... in San Diego. His presentation is entitled High altitude ...
... the UK National Stem Cell Network Annual Science Meeting ... may be harnessed to repair the damaged cartilage that ... Scientists at Cardiff University have successfully identified stem cells ... become any cell in the body like full stem ...
... role in determining a leaf,s venation pattern, according ... in the open-access journal PLoS Computational Biology. The ... properties of venation patterns, based on the assumption ... growth. These distortions appear due to the elastic ...
Cached Biology News:USF professor gives historical look at physiology and WWII air war 2USF professor gives historical look at physiology and WWII air war 3Stem cells offer cartilage repair hope for arthritis sufferers 2
(Date:6/30/2015)... ... June 30, 2015 , ... uBiome and ... insights on mechanics of fecal microbiota transplantation in C. difficile patients. , SAN ... of patients undergoing fecal microbiota transplantation (FMT) as a treatment for Clostridium difficile ...
(Date:6/30/2015)... June 30, 2015  The University of California, ... (CCE/Bio) and UC San Diego Extension announced their ... held Aug.  12 – 14, 2015, at UC ... workshop provides an intense exposure to best practices ... is well-suited to biologists, process engineers and business ...
(Date:6/30/2015)... ... June 30, 2015 , ... Smarter Alloys today ... revolutionary new archwire that allows orthodontists to simultaneously apply different forces to different ... of SmartArch. “We’re thrilled about taking SmartArch one step closer to commercial availability ...
(Date:6/29/2015)... ... 29, 2015 , ... The global microfluidics market is expected ... (2015 to 2020). The market is mainly driven by the rising geriatric population, ... However, lack of adequate healthcare and research infrastructure in emerging markets, dearth of ...
Breaking Biology Technology:uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 2uBiome and OpenBiome Partner for Microbiome Study in FMT Patients 3UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2New case studies for SmartArch orthodontic archwire paves way to product launch later this year 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5
... SPECTRAMAX APPLICATION NOTE , , ... Sunnyvale, CA 94089. , , ... The Molecular Devices SpectraMax M5 and, ... modes include, fluorescence intensity. These instruments have dual, ...
... for the Rapid Purification of Endotoxin-Free Plasmid ... ,The GenElute HP Endotoxin-Free Plasmid Maxiprep,Kit offers ... plasmid DNA. A patent-pending,endotoxin removal process has ... for purifying,high-quality, endotoxin-free DNA (≤ 0.1 EU/g).,This ...
... ,II. Product Components ,III. Materials to be ... of DNA from Plant ,V. Protocol for GenomePlex ... Amplified Products ,VII. Purification of Amplified Products , ... ,Application Guide, , I. Description ,Extracting DNA ...
Cached Biology Technology:measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 2measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 3measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 4measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 5measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 6measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 7measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 8measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 9measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 10measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 11measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 12measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 13measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 14measuring cell proliferation with SpectraMax M5, M2 and Gemini microplate readers using the CyQUANT Cell Proliferation Assay 15Introducing,GenElute HP,Endotoxin-Free Plasmid,Maxiprep Kit 2Introducing,GenElute HP,Endotoxin-Free Plasmid,Maxiprep Kit 3Introducing,GenElute HP,Endotoxin-Free Plasmid,Maxiprep Kit 4Introducing,GenElute HP,Endotoxin-Free Plasmid,Maxiprep Kit 5Protocol for GenomePlex Whole Genome Amplification from Plant 2Protocol for GenomePlex Whole Genome Amplification from Plant 3Protocol for GenomePlex Whole Genome Amplification from Plant 4Protocol for GenomePlex Whole Genome Amplification from Plant 5Protocol for GenomePlex Whole Genome Amplification from Plant 6
Mouse monoclonal [AZ24] to Polo like kinase ( Abpromise for all tested applications)....
... Applied Science, which pioneered the blending of ... Fidelity and Expand Long Template PCR Systems, ... System the first product of a ... new blend combines Taq DNA Polymerase with ...
... RY 13 5'G AATTC3' 3'CTTAA G5' Inactivation Conditions: ... ethanol precipitation. Storage Conditions: 10mM Tris-HCl (pH 7.5), ... X-100, 0.01% BSA, 50% glycerol. Shipping and Storage: ... Definition: One unit is defined as the amount ...
... Source: Bacillus globigii 5'GCCNNNN NGGC3' 3'CGGN NNNNCCG5' ... 15 min or phenol treatment followed by ... 8.0), 200mM KCl, 0.1mM EDTA, 1.0mM DTT, ... Shipped on dry ice. Store at -20C. ...
Biology Products: