Navigation Links
International Rett Syndrome Foundation awards $2M for cutting-edge Rett syndrome research
Date:10/1/2009

Ren's project addresses a very important complication of Rett syndrome, seeking to better understand the specific neuronal components, pathways and circuits controlling respiratory dysfunction. The study focuses on the respiratory circuit rhythm generator which is thought to function abnormally in Rett syndrome. While this rhythm generator can function normally during sleep, during wakefulness, it is believed that certain neuronal circuits are dysfunctional and fluctuations within specific regions of the cortex can destabilize the basic respiratory rhythm. The PI will analyze potential sources of central respiratory pattern instabilities to identify the specific circuits and pathways involved.

Yin Shen PhD University of California, San Diego (Mentor Bing Ren, PhD)
Genomic analysis of MECP2 Function

Dr. Shen will conduct an investigation into the action of MECP2 at its various different target-binding sites across the entire human genome. The study will specifically examine MeCP2 binding in stem cells both before and after these cells are encouraged to become neuronal cells. Dr. Shen will study the consequences of MECP2 knockdown at different target sites with a view to identifying critical target genes. The investigator will examine early stage neuronal precursors, and developing neurons to evaluate the epigenetic interactions of MECP2 at successive stages of development.

Anirban Paul PhD, Cold Spring Harbor Laboratory (Mentor Z. Josh Wang, PhD)
Novel Function of MeCP2 in mRNA Regulation and Implication in Rett Syndrome

Dr. Paul's project is aimed at testing a novel hypothesis related to the function of MeCP2. The investigator's preliminary data presents an entirely new facet of MeCP2 function which is that MeCP2 can function by binding directly to messenger RNA (mRNA) and potentially regulates the synthesis of downstream proteins. The project may provide new insights into the role of MeCP2 and
'/>"/>

Contact: Dr. Antony Horton
212-459-2608
International Rett Syndrome Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9 10 11 12

Related biology news :

1. International conference on endothelin
2. International event brings worlds top cancer doctors to Queens
3. Forest Service to host 2nd International Conference on Forests and Water in a Changing Environment
4. EMBO pioneers pension plan for internationally mobile postdoctoral researchers
5. International conference on CO2 sequestration processes
6. International research team seeks to unravel flatworm regeneration
7. Fujitsu PalmSecure Certified Under International Common Criteria Evaluation Assurance Level 2
8. Journal of Vascular and Interventional Radiology increases impact, international reach
9. International team of students and scientists on month-long field course in Siberian Arctic
10. ESHRE launches international study of polar body screening
11. International collaboration by scientists culminates in novel ion channels database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... -- LiveScan Service Provider Binary Biometrics is pleased to welcome Kevin ... will improve its mobile service capabilities and add more daily appointments, which will ... service several new cities such as, but not limited to, Daytona ... Deltona , Edgewater , Holly ... Beach , Oak Hill , Orange City ...
(Date:7/31/2014)... by the National Science Foundation (NSF), counters a ... atmospheric warming, indicating instead that certain Arctic lakes ... the atmosphere. , The study, published this ... on thermokarst lakes, which occur as permafrost thaws ... fresh water, converting what was previously frozen land ...
(Date:7/31/2014)... (HPV-023; NCT00518336) shows the sustained efficacy, immunogenicity ... (HPV) vaccine Cervarix. Women vaccinated with the ... than nine years, and vaccine efficacy (VE) ... the longest follow-up report for a licensed ... the full paper. , HPV and ...
Breaking Biology News(10 mins):Binary Biometrics, Founded by James Timothy White, Expands Services to 13+ Locations With the Addition of Owner/Operator Kevin Morris 2Binary Biometrics, Founded by James Timothy White, Expands Services to 13+ Locations With the Addition of Owner/Operator Kevin Morris 3Certain Arctic lakes store more greenhouse gases than they release 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 3
... the membrane of human liver cells that aids in cholesterol ... first step in hepatitis C infection, according to research at ... The cholesterol receptor offers a promising new target for anti-viral ... the researchers, whose findings were reported online in advance of ...
... has taken us a step closer to breeding hardier crops ... off attack from parasites. In a paper published in ... of the United States of America (PNAS), the researchers have ... Arabidopsis thaliana , or thale cress, by controlling an ...
... infants are helpless creatures that only blink, eat, cry ... studies indicate infant brains come equipped with knowledge of ... we study infant knowledge of the world by measuring ... Kristy vanMarle, an assistant professor in the Department of ...
Cached Biology News:Entry point for hepatitis C infection identified 2Improving crops from the roots up 2Babies are born with 'intuitive physics' knowledge, says MU researcher 2
(Date:7/31/2014)... There,s a good reason people over 60 are not ... ages and weakens with time, making the elderly prone ... San Francisco research team now has discovered a reason ... for the inability of blood-forming cells to maintain blood ... identified molecular defects that could be restored for rejuvenation ...
(Date:7/31/2014)... Chemists at Indiana University Bloomington have described the ... a development with potential value for the field ... and photovoltaic cells. , Their paper, "Anion-Induced Dimerization ... and 2D Self-Assembled Crystals," has been published online ... the Royal Society of Chemistry. It is the ...
(Date:7/31/2014)... Yonkers, NY (PRWEB) July 31, 2014 ... use in high temperature oven carts. These bearings are ... occur in sealed ball bearings because of the ... purity alumina requested help from the design engineers at ... through a heating process. During their manufacturing operation, pans ...
(Date:7/31/2014)... July 31, 2014 CollabRx, Inc. (NASDAQ: ... therapeutic decision-making in oncology, today announced that it will ... to discuss the Company's financial results for the first ... about the business in the current fiscal year. , ... on Thursday, August 14, 2014, at 5 p.m. EDT ...
Breaking Biology Technology:Key to aging immune system is discovered 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 3Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2
... 2011 Informex , the leading meeting place ... details of the Global Pharma Sourcing Conference to be ... Avenue in Philadelphia, Pennsylvania. The two day program will ... CPhI to address key issues that global chemical and ...
... The following is a letter to shareholders from ... a publicly traded portfolio of biotech companies based on ... Dear Fellow Investors, Hadasit Bio-Holdings ... Hadassah University Hospital and its IPO which made public ...
... of recent salmonella outbreaks in the United States: ground ... and the list goes on, according to the U.S. ... for long, thanks to a promising new biosensor nanotechnology ... contaminated food or animals reach the marketplace. In the ...
Cached Biology Technology:Informex Introduces a Thorough Global Pharma Perspectives Conference 2Summary Letter to Hadasit Bio-Holdings Ltd. Shareholders 2Summary Letter to Hadasit Bio-Holdings Ltd. Shareholders 3Summary Letter to Hadasit Bio-Holdings Ltd. Shareholders 4Summary Letter to Hadasit Bio-Holdings Ltd. Shareholders 5Summary Letter to Hadasit Bio-Holdings Ltd. Shareholders 6
... The Brownlee Precision Model 440 incorporates ... circuitry in a friendly easy-to-use instrument. Each ... amplifier, an 8-pole Bessel lowpass filter, a ... output offset controls. A control knob sets ...
... versatile & modular instrument which can be used ... Extracellular, Transducer & Multi-channel Isolated Amplification ... Supply unit (NL900D) forms the heart of every ... by this unit, but wiring within the case ...
Rat Epidermal Keratinocytes (REK) (>500,000 cells)...
... The Brownlee Precision Model 410 is a ... used to amplify small signals from sources which ... frequency noise. Each channel consists of a high ... 2-pole lowpass filter, and an output offset control. ...
Biology Products: