Navigation Links
Interaction of just 2 genes governs coloration patterns in mice
Date:8/13/2007

CAMBRIDGE, Mass. -- Biologists at Harvard University and the University of California, San Diego, have found that a simple interaction between just two genes determines the patterns of fur coloration that camouflage mice against their background, protecting them from many predators. The work, published this week in the journal PLoS Biology, marks one of the few instances in which specific genetic changes have been linked to an organism's ability to survive in the wild.

"Our work shows how changes in just a few genes can greatly alter an organism's appearance," says Hopi E. Hoekstra, John L. Loeb Associate Professor of the Natural Sciences in Harvard's Faculty of Arts and Sciences. "It also illuminates the pathway by which these two genes interact to produce distinctive coloration. There's reason to believe this simple pathway may be evolutionarily conserved across mammals that display lighter bellies and darker backs, from mice to tuxedo cats to German Shepherds."

Hoekstra and co-authors Cynthia C. Steiner at UCSD and Jesse Weber at Harvard studied Peromyscus, a mouse that is the most widespread mammal in North America. Within the last several thousand years, these mice have migrated from mainland Florida to barrier islands and dunes along the Atlantic and Gulf coasts, where they now live on white sand beaches. In the process, the beach mice's coats have become markedly lighter than that of their mainland brethren.

"In nature there is a tremendous amount of variation in color patterns among organisms, ranging from leopard spots to zebra stripes, that help individuals survive," says Steiner, a postdoctoral researcher in UCSD's Division of Biological Sciences. "However, we know surprisingly little about how these adaptive color patterns are generated. In this paper, we identify the genetic changes producing a simple color pattern that helps camouflage mice inhabiting the sandy dunes of Florida's Gulf and Atlantic coasts. These 'beach mi
'/>"/>

Contact: Steve Bradt
steve_bradt@harvard.edu
617-496-8070
Harvard University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Virus-host interactions at sea effect global photosynthesis
2. Future diabetes drugs may target new protein interaction
3. Computational verification of protein-protein interactions by orthologous co-expression
4. Confirmation of human protein interaction data by human expression data
5. Physical and functional interaction of key cell growth molecules linked to cancer
6. Complex gene interactions account for autism risk
7. Image of myosin-actin interaction revealed in cover story of Molecular Cell
8. A real time look at interactions between RNA and proteins
9. U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain
10. Biologists visualize protein interaction that may initiate viral infection
11. Biologists develop genome-wide map of miRNA-mRNA interactions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... grip is affecting more than the color of people,s lawns. ... heat-loving amoeba commonly found in warm freshwater bodies, such as ... warmer than usual this year. , A 9-year-old Kansas girl ... swimming in several area lakes. The amoeba enters the body ... brain. Nose plugs can lower the odds of this rare ...
(Date:7/23/2014)... commonly found in dead bodies and is used in ... to as the post mortem interval. A report of ... Tamil Nadu is provided for the first time based ... DNA barcoding. This study, significant in forensic investigations was ... . , Chrysomya megacephala is commonly found ...
(Date:7/23/2014)... around the world by 2050, according to one of ... Change (IPCC), may be advantageous to the physiology and ... of forage plants such as Stylosanthes capitata Vogel ... countries such as Brazil., The conclusion is from a ... Biology at the Ribeiro Preto Faculty of Philosophy, Sciences ...
Breaking Biology News(10 mins):Diseases of another kind 2Dead body feeding larvae useful in forensic investigations 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 3An increase in temperature by 2050 may be advantageous to the growth of forage plants 4
... Davis researchers in nanotechnology, chemistry and biology now have access ... in the world. The new Spectral Imaging Facility, opened this ... a laser scanning confocal microscope, the first commercial machine of ... Asylum Research of Santa Barbara and the confocal microscope system ...
... gained new insights into how neurons control growth ... that enable them to connect with their neighbors. ... which neurons form the signaling networks that constitute ... neuronal growth will help researchers better understand brain ...
... preliminary results from a study in Botswana, Harvard School ... HIV-1 subtype C in resource-poor settings, who receive antiretroviral ... the developed world. A fully supported health care delivery ... data published in November 2005 issue of the Journal ...
Cached Biology News:How the neuron sprouts its branches 2How the neuron sprouts its branches 3Largest computational biology simulation mimics life’s most essential nanomachine 2
(Date:7/23/2014)... 2014 - Valentis ... Trendlines Agtech , announced it has signed an ... leading agricultural thermoplastics applications companies. ... combines nanocrystalline cellulose (NCC), a biodegradable, transparent material ... to produce highly improved polymeric films. Used as ...
(Date:7/23/2014)... , July 23, 2014 ... ), the global specialty biopharmaceutical company, and ArmaGen, ... a worldwide licensing and collaboration agreement for AGT-182, ... potential treatment of both the central nervous system ... syndrome (MPS II). This collaboration strengthens Shire,s rare ...
(Date:7/23/2014)... With the ability to record continuously at over ... 15 minutes, Fastec Imaging has brought the same ease-of-use of ... “Finally, a high speed camera that can be used as ... lives.” proclaims Matt Kearney, VP of Sales for Fastec Imaging. ... and simplify the traditionally complicated workflow of a high speed ...
(Date:7/23/2014)... Astra Nova Training , ... and pharma training services, and the Alliance ... a non-profit integrating the expertise and investments of ... global system for clinical trials, are pleased to ... expertise of industry professionals through improved and easily ...
Breaking Biology Technology:Valentis Nanotech Signs MOU to Integrate Technology in Thermoplastics Production 2Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 2Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 3Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 4Shire Enters Strategic Licensing and Collaboration Agreement With ArmaGen 5Fastec Imaging Introduces the First High Speed Camcorder 2Fastec Imaging Introduces the First High Speed Camcorder 3Astra Nova and ACRES Partner on Quality and Access of Training for Research Professionals 2Astra Nova and ACRES Partner on Quality and Access of Training for Research Professionals 3
... Building the Merge Healthcare of tomorrow, as ... offshoring 150 jobs to a "more cost effective workforce" ... of the financially troubled medical imaging software company's workforce ... the competitive edge marks the centerpiece of a broader ...
... - TeraMedica , a medical informatics company, has ... the VisLite Information Manager , an ... , ,The product integrates and manages advanced and traditional ... records and health records. , ,It also uses open ...
... spend the most on research and development in the life ... University of Wisconsin-Madison ($764 million) is perennially among the ... the list is the Medical College of Wisconsin ... research centers. Next up is the University of Wisconsin-Milwaukee ...
Cached Biology Technology:Merge offshoring jobs to "more cost-effective" workforce 2Merge offshoring jobs to "more cost-effective" workforce 3Marshfield Clinic and UW combine to speed tech growth 2Marshfield Clinic and UW combine to speed tech growth 3Marshfield Clinic and UW combine to speed tech growth 4
Recombinant Mouse LIGHT/TNFSF14...
TAR DNA binding protein...
D-biotin *50 mM aqueous solution* Secondary Detection Biotin–Avidin Detection Reagents Other...
6-(2,4-dinitrophenyl)aminohexanoic acid, succinimidyl ester (DNP-X, SE)...
Biology Products: