Navigation Links
Insulin signaling key to caste development in bees
Date:7/14/2010

What makes a bee grow up to be a queen? Scientists have long pondered this mystery. Now, researchers in the School of Life Sciences at Arizona State University have fit a new piece into the puzzle of bee development. Their work not only adds to understanding about bees, but also adds insights into our own development and aging.

The study, which appeared in the June 30 online edition of Biology Letters, shows that a key protein in the insulin signaling pathway plays a strong role in caste development among bees.

A female bee can become either a worker or a queen. Queen bees are larger and live longer than workers. Queen bees are also fertile while workers are essentially sterile. A queen has only one roleto lay eggswhile workers tend the hive, care for the queen and larvae, and forage for food.

"The incredible thing is that both of these types of female honeybees emerge from the same genome," says Florian Wolschin, an assistant research professor in the School of Life Sciences in ASU's College of Liberal Arts and Sciences, is the lead author of the study. "So how does that happen?"

Workers determine the fate of the larvae by what they feed them. The amount and composition of food that the larvae receive determine whether they become workers or queens. People have known this for many years, but exactly what happens inside the cells to create this split isn't completely clear.

Wolschin, Gro Amdam, an associate professor, and Navdeep S. Mutti, a postdoctoral research associate, found that the insulin signaling pathway plays a role in caste development. Insulin is a hormone found in humans and many other animals, and insulin-like peptides have been discovered in bees. Insulin moves glucosesugarfrom the bloodstream into the body's cells where it can be used.

The researchers suppressed one of the key proteins in this pathway in honeybee larvae. The protein, called the insulin receptor substrate (IRS), h
'/>"/>

Contact: Margaret Coulombe
margaret.coulombe@asu.edu
480-727-8934
Arizona State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. For insulin sensitive overweight patients, 1 session of exercise improves metabolic health
2. Decreasing insulin resistance prevents obesity-related cardiovascular damage
3. Findings show insulin -- not genes -- linked to obesity
4. Nanodiamonds deliver insulin for wound healing
5. Pitt study finds molecular link between insulin resistance and inflammation
6. Diabetes advance: Researchers find gene that causes resistance to insulin
7. CHEO RI study uses sophisticated genetic engineering to improve insulin-producing beta cells
8. New gene variants associated with glucose, insulin levels, some with diabetes risk
9. Scripps research scientists find new link between insulin and core body temperature
10. Structure of insulins docking point identified
11. Insulin-like signal needed to keep stem cells alive in adult brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Insulin signaling key to caste development in bees
(Date:7/9/2014)... Sexual selection refers to species, selection for traits that ... of natural selection enhances opportunities to mate, the tail ... at the University of California, Riverside have now found ... a placenta are linked. Describing the life histories ... family Poeciliidae, the researchers found that species with placentas ...
(Date:7/9/2014)... (TCGA) Research Network have identified novel mutations in ... most common subtype of lung cancer. Knowledge of ... possible therapeutic targets for this disease and potentially ... mutations because many potent cancer drugs that target ... funded and managed by the National Cancer Institute ...
(Date:7/9/2014)... With grilling season upon us, many backyard cooks are ... fatty hot dogs. But low fat can sometimes mean ... addressing the texture problem in low-fat wieners that are ... study was published in ACS, Journal of Agricultural ... colleagues note that hot-dog consumers have come to expect ...
Breaking Biology News(10 mins):Biologists link sexual selection and placenta formation 2Biologists link sexual selection and placenta formation 3Biologists link sexual selection and placenta formation 4Study identifies novel genomic changes in the most common type of lung cancer 2Study identifies novel genomic changes in the most common type of lung cancer 3
... those hoping to start or extend a family should ... Current clinical guidelines already recommend that women who are ... based on the knowledge that cholesterol is essential for ... the risk of congenital anomalies in children of pregnant ...
... pollution are decreasing the growth of trees in the northern ... in Global Change Biology . Tree growth, measured ... and this is set to increase to a 17% reduction ... four times greater now than prior to the Industrial Revolution ...
... momentum of,September,s impressive showing at the ePassports EAC Conformity ... advances its role as the,world,s ePassport leader by being ... advanced second-generation ePassports based on the,Extended Access Control (EAC) ... ePassports represent the beginning of an evolution that,will improve ...
Cached Biology News:Statin warning for pregnant women 2Surface-level ozone pollution set to reduce tree growth 10 percent by 2100 2The Finnish Population Register Centre to Deploy Entrust EAC ePassport CA Solution 2The Finnish Population Register Centre to Deploy Entrust EAC ePassport CA Solution 3The Finnish Population Register Centre to Deploy Entrust EAC ePassport CA Solution 4
(Date:1/15/2014)... 15, 2014 2013 was a banner ... State Technologies®. They saw continued independent research led by ... were awarded a $1 million grant from the Susanne ... and Behavior” a peer reviewed journal, Amy Grant highlighted ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 p.m. – ... Warrington, Pa. , Details: The Hepatitis B Foundation, ... cure for hepatitis B and improving the quality of life ... on Friday, April 11 at Warrington Country Club in Warrington, ...
(Date:1/14/2014)... pet owners drew up their lists of New Year,s resolutions for ... of my furry companion." Nowadays there are pet salons, dog and ... take the little canine or feline darlings along wherever mommy or ... pricey toys at the pet store. But anyone who has ever ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2
... Sept. 8 /PRNewswire-FirstCall/,-- Concuity, a healthcare division ... a leading,provider of contract management and revenue ... today announced that Valley Baptist Health,System has ... more,accurately calculate payments from managed care and ...
... (Nasdaq: CTICD ; and MTA: CTIC) announced ... Listing Qualifications Staff of The NASDAQ Stock,Market LLC ... with the,$50,000,000 minimum market value of listed securities ... the Company does not,comply with NASDAQ Marketplace Rule ...
... Just as test pilots push planes to explore ... Standards and Technology (NIST) are probing the newest ... the nanoscale. Better nanoscale measurements are critical for ... and nanomanufacturing industries. , This new microscope technology ...
Cached Biology Technology:Valley Baptist Health System Selects Concuity's ClearContracts to More Accurately Calculate Payments from Managed Care and Government Payers 2Valley Baptist Health System Selects Concuity's ClearContracts to More Accurately Calculate Payments from Managed Care and Government Payers 3Valley Baptist Health System Selects Concuity's ClearContracts to More Accurately Calculate Payments from Managed Care and Government Payers 4CTI Receives NASDAQ Letter 2CTI Receives NASDAQ Letter 3NIST studies how new helium ion microscope measures up 2
... SYBR Green II RNA gel stain ... has bright fluorescence when bound to RNA and ... use with either formaldehyde/agarose or polyacrylamide gels using ... stains 50 minigels. A 1 mL unit size ...
Sirtuin 7 (SIRT7) Rabbit anti-Human Polyclonal Antibody Immunogen: Synthetic peptide - KLH conjugated Family: Other Recommended Storage: Long term: -20C; Short term: +4C...
... RSH-4000 is the only microplate sealer with ... long walkaway times with a variety of ... Fully automated with integrated stacker and 240-plate ... EX for use in small workcells , ...
... Reagents for the differentiation of mouse embryonic ... bodies exist in the midbrain, where they ... the ventral tegmental area, and the retrorubral ... to extensive forebrain dopamine innervation ( e.g.projections ...
Biology Products: