Navigation Links
Insulin signaling key to caste development in bees
Date:7/14/2010

What makes a bee grow up to be a queen? Scientists have long pondered this mystery. Now, researchers in the School of Life Sciences at Arizona State University have fit a new piece into the puzzle of bee development. Their work not only adds to understanding about bees, but also adds insights into our own development and aging.

The study, which appeared in the June 30 online edition of Biology Letters, shows that a key protein in the insulin signaling pathway plays a strong role in caste development among bees.

A female bee can become either a worker or a queen. Queen bees are larger and live longer than workers. Queen bees are also fertile while workers are essentially sterile. A queen has only one roleto lay eggswhile workers tend the hive, care for the queen and larvae, and forage for food.

"The incredible thing is that both of these types of female honeybees emerge from the same genome," says Florian Wolschin, an assistant research professor in the School of Life Sciences in ASU's College of Liberal Arts and Sciences, is the lead author of the study. "So how does that happen?"

Workers determine the fate of the larvae by what they feed them. The amount and composition of food that the larvae receive determine whether they become workers or queens. People have known this for many years, but exactly what happens inside the cells to create this split isn't completely clear.

Wolschin, Gro Amdam, an associate professor, and Navdeep S. Mutti, a postdoctoral research associate, found that the insulin signaling pathway plays a role in caste development. Insulin is a hormone found in humans and many other animals, and insulin-like peptides have been discovered in bees. Insulin moves glucosesugarfrom the bloodstream into the body's cells where it can be used.

The researchers suppressed one of the key proteins in this pathway in honeybee larvae. The protein, called the insulin receptor substrate (IRS), h
'/>"/>

Contact: Margaret Coulombe
margaret.coulombe@asu.edu
480-727-8934
Arizona State University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. For insulin sensitive overweight patients, 1 session of exercise improves metabolic health
2. Decreasing insulin resistance prevents obesity-related cardiovascular damage
3. Findings show insulin -- not genes -- linked to obesity
4. Nanodiamonds deliver insulin for wound healing
5. Pitt study finds molecular link between insulin resistance and inflammation
6. Diabetes advance: Researchers find gene that causes resistance to insulin
7. CHEO RI study uses sophisticated genetic engineering to improve insulin-producing beta cells
8. New gene variants associated with glucose, insulin levels, some with diabetes risk
9. Scripps research scientists find new link between insulin and core body temperature
10. Structure of insulins docking point identified
11. Insulin-like signal needed to keep stem cells alive in adult brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Insulin signaling key to caste development in bees
(Date:10/14/2014)... tumors scavenge and hoard copper that is an essential ... a fatal weakness. , Researchers at Duke Medicine ... by delivering a trove of copper along with a ... the mineral, leaving non-cancer cells healthy. , The combination ... other uses, could soon be tested in clinical trials ...
(Date:10/14/2014)... been millions of years since T. rex ... Ohio University scientists is breathing life back into dinosaurs ... snouts. The research has important implications for how dinosaurs ... enhance the sense of smell and cool their brains. ... University doctoral student Jason Bourke, lead author of the ...
(Date:10/14/2014)... One of the planet,s leading questions is how to ... increasingly variable climate. The Food and Agriculture Organization of ... 70% over the next 40 years to feed a ... of the necessary rise in food production. Plants—grains, ... by supporting livestock. Current research must tap into ...
Breaking Biology News(10 mins):Prostate cancer's penchant for copper may be a fatal flaw 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
... 2009 -- A new study conducted at Ben-Gurion University ... anti-inflammatory coxib medications may counter the positive effects of ... in the Proceedings of the National Academy of ... are taking aspirin and coxibs together are in fact ...
... structure of new anti-cancer agents has enabled a team of ... halting a common type of drug-resistant lung cancer. In ... of the journal Nature , the researchers report that ... drugs Iressa and Tarceva were stymied by a compound designed ...
... The journeys of two marine turtles around the world,s oceans ... a new research project launched by the University of Exeter. ... turtles that nest in Gabon, Western Central Africa. The research ... device, which enables the scientists to monitor their precise movements ...
Cached Biology News:Research yields new agent for some drug-resistant non-small cell lung cancers 2Research yields new agent for some drug-resistant non-small cell lung cancers 3Turtles' Christmas journey tracked by scientists 2
(Date:10/20/2014)... 20, 2014 Local veterinary surgeon, Dr. ... investigational study of donor stem cells for dogs with ... therapy and has performed clinical stem cell therapy for ... to determine if a single injection of donor stem ... help reduce pain and inflammation in the treated joints. ...
(Date:10/19/2014)... 2014 OCTOBER 20-22, 2014: ... ABIM will take place at the ... ABIM 2014 is now available at ... companies and organizations from all over the ... on the latest products and developments on ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 The ... bromine market in Asia-Pacific with analysis and forecast ... the Asia Pacific Bromine Market report, to get ... also provides a glimpse of the segmentation in ... various tables and figures. , http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html ...
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report defines and segments ... forecast of revenue. This market is estimated to grow ... 2019, at a Compound Annual Growth Rate (CAGR) of ... TOC of the Asia-Pacific Speech Analytics market report to ... also provides a glimpse of the segmentation in the ...
Breaking Biology Technology:Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
... NEW YORK, MUNICH, Germany and AMSTERDAM, Netherlands, ... Holding, B.V., the,pan-European specialty pharmaceutical company, today ... 10 million revenue interest acquisition financing,agreement to ... and,certain other markets, from Procter & Gamble ...
... Va., Aug. 20 Inc. magazine announced,its 27th annual ... country. Federal Information Technology (IT) services provider,MicroTech, ranks No. ... The 2008 Inc. 500 list measures revenue growth ... U.S.-based, privately held, independent -,no subsidiaries or divisions of ...
... Eli Lilly and,Company (NYSE: LLY ) today announced ... (Nasdaq: SGXP ), a San Diego-based,biotechnology company focused ... The completion of the deal followed today,s Special,Stockholders Meeting, ... of the merger agreement with Lilly. Under the agreement, ...
Cached Biology Technology:TVM Capital, Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 2TVM Capital, Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 3TVM Capital, Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 4TVM Capital, Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm 5MicroTech Ranks No. 285 on Inc. Magazine's 2008 List of the 500 Fastest Growing Private Companies in America 2Lilly Announces Completion of SGX Acquisition 2
Molecular Biology grade. Ideally suited for DNA and RNA separation and recovery. High gel strength. Gelling temp. 36C. Melting temp. 88C. EEO: 0.05-0.13 Resolution 0.2-40 kb; Rnase/Dnase: none detec...
... offers the most comprehensive, cost-effective solution ... have incorporated unprecedented quality into both ... includes proven detection chemistries and antibodies ... TechMate protocol. It also includes our ...
Human Cell Line Slides...
Mouse Cell Line Slides...
Biology Products: