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Insulin offers new hope for the treatment of acute pancreatitis
Date:8/21/2014

e that insulin directly protects the acinar cells, which is where the disease is initiated.

Dr Bruce explains: "Insulin works by restoring the energy levels of pancreatic acinar cells, which fuels the calcium pumps on the membrane of these cells. These calcium pumps help to restore cellular calcium and prevent the catastrophic cell death and autodigestion of the pancreas."

He continues: "Although more research is needed to confirm that insulin works in animal models and human clinical trials, this study suggests that combined with tight control over blood glucose insulin may be an effective treatment for pancreatitis. Furthermore, if we can better understand how insulin works, then we might be able to design new and more effective drugs that might one day provide the first curative treatment for this disease"


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Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert  

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