Navigation Links
Insight into cells could lead to new approach to medicines

A surprising discovery about the complex make-up of our cells could lead to the development of new types of medicines, a study suggests.

Scientists studying interactions between cell proteins which enable the cells in our bodies to function have shown that proteins communicate not by a series of simple one-to-one communications, but by a complex network of chemical messages.

The findings suggest that medicines would be more effective if they were designed differently. Drugs could have a greater effect on cell function by targeting groups of proteins working together, rather than individual proteins.

Results were obtained by studying yeast, which has many corresponding proteins in human cells. Researchers, including scientists from the University of Edinburgh, used advanced technology to identify hundreds of different proteins, and then used statistical analysis to identify the more important links between them, mapping almost 2000 connections in all.

Scientists expected to find simple links between individual proteins but were surprised to find that proteins were inter-connected in a complex web.

Dr Victor Neduva, of the University of Edinburgh, who took part in the study, said: "Our studies have revealed an intricate network of proteins within cells that is much more complex than we previously thought. This suggests that drugs should be more complex to treat illnesses effectively.

Professor Mike Tyers, who led the study, said: "Medicines could work better if they targeted networks of proteins rather than sole proteins associated with particular illnesses."


Contact: Catriona Kelly
University of Edinburgh

Page: 1

Related biology news :

1. Instant acid method offers new insight into nanoparticle dispersal in the environment and the body
2. Researchers share insights into RNA
3. New insights into how deadly amphibian disease spreads and kills
4. Paper offers new insights into the genomics of speciation
5. Neanderthal genome yields insights into human evolution and evidence of interbreeding
6. New Stanford-led program aims to produce insights into brain injury, recovery
7. Study provides new insights into the implications of autism onset patterns
8. New insights into treatment options for patients suffering from severe alcoholic hepatitis
9. Primary cilia formation provides insight into genetic diseases
10. Singapore program to provide clinical insight; showcase for regional research
11. Sea creatures sex protein provides new insight into diabetes
Post Your Comments:
(Date:6/30/2017)... 2017 Today, American Trucking Associations announced ... face and eye tracking software, became the newest ... "Artificial intelligence and advanced sensing ... a driver,s attentiveness levels while on the road.  ... detect fatigue and prevent potential accidents, which could ...
(Date:5/16/2017)... , May 16, 2017   Bridge Patient ... organizations, and MD EMR Systems , an ... partner for GE, have established a partnership to ... product and the GE Centricity™ products, including Centricity ... These new integrations will allow ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... Annual Report on Form 10-K on Thursday April 13, 2017 with ... ... Relations section of the Company,s website at  under "SEC ... . 2016 Year Highlights: Acquisition ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... , ... October 10, 2017 , ... Dr. Bob Harman, ... his local San Diego Rotary Club. The event entitled “Stem Cells ... and had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program Committee ... honoring scientists who have made outstanding contributions to analytical chemistry and applied ... the world’s leading conference and exposition for laboratory science, which will be held ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving Tree Wellness ... targeting the needs of consumers who are incorporating medical marijuana into their wellness ... Arizona. , As operators of two successful Valley dispensaries, The Giving Tree’s two ...
(Date:10/7/2017)... , Oct. 6, 2017  The 2017 Nobel ... three scientists, Jacques Dubochet, Joachim Frank ... in cryo-electron microscopy (cryo-EM) have helped ... the structural biology community. The winners worked with ... now routinely produce highly resolved, three-dimensional images of ...
Breaking Biology Technology: