Navigation Links
Insect glands may illuminate human fertilization process
Date:5/3/2012

Baltimore, MD Insect glands are responsible for producing a host of secretions that allow bees to sting and ants to lay down trails to and from their nests. New research from Carnegie scientists focuses on secretions from glands in the reproductive tract that help sperm survive and guide the sperm on the trip to fertilize an egg. The gene that controls the development of these glands in fruit flies provides important information about gland development in all insects, as well as potential clues to similar human reproductive glands. Their work is published this month in Current Biology.

When a female fruit fly receives sperm from a male fruit fly, lubricating secretions in her reproductive tract activate the sperm, store it and guide it to fertilization. Without the aid of these secretions, sperm would not make it to the eggs. Carnegie's Allan Spradling and Jianjun Sun demonstrated that the gene in charge of regulating the development of fruit fly secretion glands is called Hr39. It encodes a steroid receptor protein.

Mutant fruit flies that lack this gene have no such glands formed in the reproductive tract and are infertile. However, their formation could be partially restored with the expression of a mouse gene that encodes an analogous steroid receptor in mammals called Lrh-1. Mutant mice that lack this gene are also infertile.

The work demonstrates that even though it has been millions of years since there was a common ancestor that links fruit flies to miceand, more generally, insects to mammalsthese similar genes are still in charge of at least some of the same functions.

Secretions from reproductive glands in mammals are thought to assist sperm in undergoing similar changes to facilitate fertilization. But studying this process has proved difficult. Knowing that the functions of Hr39 in fruit flies and Lrh-1 in mammals are similar in this regard will facilitate research.

"The fruit fly work in our paper provides a method for studying the cellular physiology governing this reproductive secretion process more quickly, cheaply and effectively than we had previously thought possible," Spradling said.


'/>"/>

Contact: Jianjun Sun
sun@ciwemb.edu
Carnegie Institution
Source:Eurekalert

Related biology news :

1. Researchers uncover worlds oldest fossil impression of a flying insect
2. Honey bees on cocaine dance more, changing ideas about the insect brain
3. Florida professor creates endowment for insect scientists
4. Termite insecticide a potent greenhouse gas
5. A natural, alternative insect repellent to DEET
6. Ecological insect pest management for Guam
7. Exposure to insecticide may play role in obesity epidemic among some women
8. Study assesses impact of fish stocking on aquatic insects
9. Team approach appears to work best for insect colonies
10. NIH funds development of resistance-breaking insecticides to reduce malaria transmission
11. IVCC and Syngenta start project for novel insecticidal active ingredient for malaria control
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
(Date:4/14/2016)... Israel , April 14, 2016 ... Authentication and Malware Detection, today announced the appointment of ... assumed the new role. Goldwerger,s leadership appointment ... on the heels of the deployment of its platform ... BioCatch,s behavioral biometric technology, which discerns unique cognitive and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
(Date:6/23/2016)... 23, 2016 On Wednesday, June 22, ... down 0.22%; the Dow Jones Industrial Average edged 0.27% lower ... 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the following ... Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ... BIND ). Learn more about these stocks by accessing ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... a new line of intelligent tools designed, tuned and optimized exclusively for Okuma ... 12–17 in Chicago. The result of a collaboration among several companies with expertise ...
(Date:6/22/2016)... DIEGO , June 22, 2016 ... that will allow them to produce up to ... from one lot within one week. These high-quality, ... time laboriously preparing cells and spend more time ... possible through a proprietary, high-volume manufacturing process that ...
Breaking Biology Technology: