Navigation Links
Ingredient in turmeric spice when combined with anti-nausea drug kills cancer cells
Date:8/20/2013

cology Research, associate director for translational research, program co-leader of Developmental Therapeutics and Cancer Cell Signaling research member at VCU Massey Cancer Center.

The hybrid molecules of turmeric and thalidomide created more than 15 compounds, each with a different effect. Scientists found that compounds 5 and 7 exhibited superior cell toxicity compared to curcumin alone or the combination of curcumin and thalidomide. Furthermore, the compounds were found to induce significant multiple myeloma cell death.

"Overall, the combination of the spice and the drug was significantly more potent than either individually, suggesting that this hybrid strategy in drug design could lead to novel compounds with improved biological activities," added Grant. "The results also strongly encourage further optimization of compounds 5 and 7 to develop more potent agents as treatment options for multiple myeloma."


'/>"/>

Contact: Alaina Farrish
akfarrish@vcu.edu
804-628-4578
Virginia Commonwealth University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
2. Study sheds new light on importance of human breast milk ingredient
3. New oil spill dispersant made from ingredients in peanut butter, chocolate, ice cream
4. A sip of resveratrol and a full p53: Ingredients for a successful cell death
5. New and revised standards for omega-3s, natural sweeteners and other food ingredients proposed
6. Discoveries suggest icy cosmic start for amino acids and DNA ingredients
7. New DNA test identifies ingredients in foods
8. Recipe for large numbers of stem cells requires only one ingredient, says NIH/Pitt team
9. New technologies and ingredients provide better options for gluten-free eating
10. A greener, more sustainable source of ingredients for widely used plastics
11. Turmeric spices up virus study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... threats in today,s ocean. From overfishing and pollution ... ecosystems are disappearing at unprecedented rates around the ... surrounding the island of Moorea in French Polynesia ... coral guard-crabs. New research from the National Museum ... McKeon and the museum,s predoctoral fellow Jenna Moore ...
(Date:9/29/2014)... the exposure to tar tended to be lower for ... Similarly, exposure to nicotine tended to be lower. , ... in several countries around the world. Previous studies have ... the smoke of these cigarettes are lower than those ... in the smoke are not necessarily linked to a ...
(Date:9/29/2014)... in school? According to a new Food and Brand ... meals can increase participation in the National School Lunch ... of vegetables by 16%! , Chefs Move to Schools ... pairs chefs with schools in order to provide nutrition ... food service workers. , A CMTS event was held ...
Breaking Biology News(10 mins):Smithsonian scientists discover coral's best defender against an army of sea stars 2Slim cigarette smokers not exposed to more harmful chemicals 2Chefs move to schools can increase school meal participation and vegetable intake among students 2
... , This release is available in German . ... chemically fix, stain or cut cells in order to study them. ... environment. The new method delivers an immediate 3-D image, thereby closing ... a high-resolution 3-D image of the entire cell in one step. ...
... Mass. Although people infected with HIV produce many antibodies ... are strangely ineffective at fighting the disease. A new study ... don,t work: they target the protein in a form it ... it,s too late, report researchers at Children,s Hospital Boston and ...
... Madrid, Friday November 19th, 2010. It is estimated ... / 10,000 people- affect about 6% of the European population. ... risk of having a newborn with a severe syndrome of ... affected by one of these diseases, being the most common ...
Cached Biology News:New microscope reveals ultrastructure of cells 2Designing more effective anti-HIV antibodies 2Designing more effective anti-HIV antibodies 3Spain is leading the fight against rare anemias in Europe 2
(Date:10/1/2014)... San Francisco, California (PRWEB) October 01, 2014 ... grant from the National Science Foundation to expand their ... approaches to build and modify DNA. The Small Business ... help commercialize the “j5” technology under exclusive license from ... the Joint BioEnergy Institute , an LBNL laboratory ...
(Date:9/30/2014)... 2014 Applying a well-known optical phenomenon called ... University has demonstrated the ability to "paint" ultra-thin ... holds promise for making future, flexible electronic devices, ... of next-gen rocket ships and spacecraft with extremely ... oil in water, it becomes iridescent, revealing a ...
(Date:9/30/2014)... 30, 2014 Shimadzu Scientific Instruments ... easy-to-use and highly precise tool for measuring displacement ... elongation. With 1000-mm maximum movement distance, the DSES-1000 ... a gauge length of 10 mm. In addition, ... above 50-mm stroke and within +/- 100 µm ...
(Date:9/30/2014)... 30, 2014  RegeneRx Biopharmaceuticals, Inc. (OTC: RGRX) ... has received a Canadian Patent for Inhibition or ... patent includes claims using thymosin beta 4, various ... for these purposes.  The patent will expire in ... ( www.regenerx.com ) RegeneRx is ...
Breaking Biology Technology:TeselaGen Receives $750k NSF SBIR Phase II Award 2TeselaGen Receives $750k NSF SBIR Phase II Award 3Taking thin films to the extreme 2Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2RegeneRx Receives Canadian Patent for Inhibition or Reversal of Skin Aging 2
... LOS ALAMOS, New Mexico, December 13, 2007In collaboration ... Alamos, an international team of researchers has, for ... formation of mysterious metallic puddles that facilitate the ... electrically conducting one. , The research may lead ...
... SAN DIEGO, Dec. 13 Neurocrine Biosciences,Inc. (Nasdaq: ... at its San Diego campus, as a part of ... and associated costs,and expenses after the setback on indiplon. ... "It is with great disappointment that we have to ...
... GRENOBLE France, December 13 ,STALLERGENES S.A and Protein,eXpert ... developing and pharmaceutically producing mites,recombinant allergens(1)., The ... programme for a recombinant protein treatment for sublingual,desensitisation ... up of the recombinant allergens Der p 1 ...
Cached Biology Technology:Collaboration yields 'the right glasses' for observing mystery behavior in electrons 2Collaboration yields 'the right glasses' for observing mystery behavior in electrons 3Neurocrine Announces Work Force Restructuring 2Neurocrine Announces Work Force Restructuring 3STALLERGENES and Protein' eXpert Enter Into a Partnership for Producing Mites Recombinant Allergens 2STALLERGENES and Protein' eXpert Enter Into a Partnership for Producing Mites Recombinant Allergens 3