Navigation Links
Infection in malaria-transmitting mosquito discovered
Date:6/6/2014

Boston, MA Researchers have found the first evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, the major vectors of malaria in Africa. The infection, called Wolbachia, has been shown in labs to reduce the incidence of pathogen infections in mosquitoes and has the potential to be used in controlling malaria-transmitting mosquito populations.

"Wolbachia is an interesting bacterium that seems perfectly suited for mosquito control. However, there were strong doubts that it could ever be used against field Anopheles populations," said Flaminia Catteruccia, associate professor of immunology and infectious diseases at Harvard School of Public Health (HSPH) and at the University of Perugia, Italy. "We were thrilled when we identified infections in natural mosquito populations, as we knew this finding could generate novel opportunities for stopping the spread of malaria."

The study appears online June 6, 2014 in Nature Communications. Anopheles mosquitoes are the deadliest animal on the planet. They are responsible for transmitting malaria, which causes more than 600,000 deaths each year and puts half of the world's population at risk for diseases. Wolbachia infections spread rapidly through wild insect populations by inducing a reproductive phenomenon called cytoplasm incompatibility (CI), and 66% of arthropod species are infected. However, it was commonly thought that Anopheles mosquitoes were not natural hosts for Wolbachia infections, and attempts to identify infections in these mosquitoes in the field had failed.

Co-author Francesco Baldini, from University of Perugia, Italy and HSPH, in collaboration with researchers from CNRS, France, collected Anopheles mosquitoes from villages in Burkina Faso, West Africa, and analyzed their reproductive tracts. Their objective was to identify all the bacteria in the reproductive systems of both male and female mosquitoes; they were not looking directly for Wolbachia. To their surprise, they found a novel strain of the infection, which they named wAnga.

The researchers say they can now investigate whether the wAnga strain shares properties with other Wolbachia strains, which could make control strategies possible by inducing CI and reducing Plasmodium (the parasite that causes malaria) numbers in Anopheles mosquitoes in the field. "If successful, exploiting Wolbachia infections in malaria mosquitoes could reduce the burden of the disease globally," said co-author Elena Levashina, from the Max Planck Institute for Infection Biology, Berlin.


'/>"/>

Contact: Todd Datz
tdatz@hsph.harvard.edu
617-432-8413
Harvard School of Public Health
Source:Eurekalert

Related biology news :

1. Columbia Nursing study exposes infection risks in home health
2. Genome sequences show how lemurs fight infection
3. Painkillers may decrease susceptibility to recurring urinary infections
4. Humans and companion animals harbor the same types of MRSA infections
5. Immune cells outsmart bacterial infection by dying, Penn Vet study shows
6. Involvement of a gene in lentivirus infections of sheep and goats has been established
7. Viral infections: Identifying the tell-tale patterns
8. Genetics can explain why infections can trigger rheumatoid arthritis
9. Among US children, more infections caused by drug-resistant bacteria
10. Gut bacteria can cause life-threatening infections in preterm babies
11. Microbes help to battle infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2017)... 7, 2017 Report Highlights The ... from $8.3 billion in 2016 at a compound annual ... Report Includes - An overview of the global ... with data from 2015 and 2016, and projections of ... of the market on the basis of product type, ...
(Date:2/3/2017)... , Feb. 3, 2017  Texas Biomedical Research Institute announced ... Larry Schlesinger as the Institute,s new President and ... effective May 31, 2017. He is currently the Chair of ... the Center for Microbial Interface Biology at Ohio State University. ... the new President and CEO of Texas Biomed," said Dr. ...
(Date:2/1/2017)... IDTechEx Research, a leading provider of independent market research, ... a new report, Sensors for Robotics: Technologies, Markets and Forecasts ... ... Revenues ... "Sensors for Robotics: Technologies, Markets and Forecasts 2017-2027: Machine vision, force ...
Breaking Biology News(10 mins):
(Date:2/24/2017)... MA (PRWEB) , ... February 24, 2017 , ... ... replacement (TDR) procedures can be safely completed in an ambulatory surgery center (ASC) ... fusion (ACDF) procedures and previous two-year TDR studies. , Jake Lubinski, president ...
(Date:2/24/2017)... DIEGO , Feb. 24, 2017  Aethlon Medical, ... following note authored by its Chairman and CEO, ... at the Munich Security Conference last Saturday, Bill ... virus could kill more people than nuclear weapons. Mr. ... U.S. and U.K. intelligence agencies, that scientific terrorists have ...
(Date:2/24/2017)... ... February 24, 2017 , ... FireflySci, Inc is an explosive small business that ... the goal of bringing their powerful cuvette and spectrophotometer calibration to the ... FireflySci is going on as they add yet another mark on the global map. ...
(Date:2/23/2017)... and NEW YORK , ... Lumeon , a leading digital health company, ... a provider of telemedicine and remote patient monitoring, ... for telemedicine reimbursements.  DN Telehealth ... patients, in real-time, extending consultations beyond a physical ...
Breaking Biology Technology: