Navigation Links
Industry group release testing recommendations for oligonucleotide-based therapeutics
Date:7/8/2014

New Rochelle, NY, July 8, 2014Novel oligonucleotide-based drugs in development offer promising alternatives for treating a range of diseases. A group of industry and regulatory scientists developing these new nucleic acid-based therapies released consensus recommendations for evaluating the pharmacological safety of oligonucleotide therapeutics. The document is published in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. The article is available on the Nucleic Acid Therapeutics website.

Cindy Berman and coauthors from Pfizer Pharmaceuticals, GlaxoSmithKline, Preclinsight, Merck Sharp & Dohme Corp., Tepper Nonclinical Consulting, and Isis Pharmaceuticals provide the consensus opinion of the Safety Pharmacology Subcommittee of the Oligonucleotide Safety Working Group in the article "Recommendations for Safety Pharmacology Evaluations of Oligonucleotide-Based Therapeutics." The recommendations emphasize in particular the importance of safety pharmacology studies to evaluate the potential effects of systemically administered oligonucleotide-based drugs on cardiovascular function.

"It is our hope that during this period of rapid advancement both regulators and researchers alike will recognize and benefit from these carefully considered safety testing recommendations," says Executive Editor Graham C. Parker, PhD, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of Michigan, Detroit, MI.


'/>"/>

Contact: Kathryn Ruehle
kruehle@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. Gray seals consume as much fish as the fishing industry catches
2. Saving forests? Take a leaf from insurance industrys book
3. Global Laboratory Automation Industry
4. How will the US biotechnology industry benefit from new patent laws?
5. NIST launches new website to educate industry about alternatives to mercury thermometers
6. Work starts on fossil fuel free cargo ship set to transform shipping industry
7. Pilot Results Move GHX Closer to Delivery of Healthcare Industrys First Implantable Device Supply Chain Solution
8. Food industrys high-quality co-streams used effectively as raw material for new products
9. Remarkable enzyme points the way to reducing nitric acid use in industry
10. Crank Software Selects TREW Marketing for Embedded Industry Outreach
11. Plastic packaging industry is moving towards completely bio-based products
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Industry group release testing recommendations for oligonucleotide-based therapeutics
(Date:7/22/2020)... ... July 21, 2020 , ... USDM Life ... and compliance, announces a new solution to manage regulated workloads on Microsoft Azure. ... their technology stack complies with FDA and global regulations. USDM's new managed service ...
(Date:7/4/2020)... ... July 03, 2020 , ... Aesthetics Biomedical (ABM), a ... awards for not only the products and treatments developed, but also the dedicated ... RF. All the brands built by ABM have received several honors already for ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... software solutions for biopharmaceutical R&D, today announced that it has entered into ... full-length multispecific antibodies (Multiclonics®), to support their translational and clinical research strategy ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... , ... dicentra , a leading Contract Research Organization ... pleased to announce that Charles Galea has joined its clinical trials division as ... accomplished and results-driven sales executive with over 10 years of expertise in business ...
(Date:7/10/2020)... (PRWEB) , ... July 09, ... ... biotechnology company, announced today that Massachusetts Institute of Technology (MIT) has expanded ... broader license allows PathSensors to move into the point-of-care diagnostic market, focusing ...
(Date:7/10/2020)... ... 2020 , ... Sentien Biotechnologies, Inc., a clinical-stage biotechnology company ... Nissenson, M.D., F.A.C.P., as its Chief Medical Officer. Dr. Nissenson will join ... Dr. Nissenson serves as an Emeritus Professor of Medicine at the David ...
(Date:7/7/2020)... ... , ... Bio-IT World has announced the winners of the ... of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia Alliance were honored. ... examples of how technology innovations and strategic initiatives can be powerful forces for ...
Breaking Biology Technology: