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Increased nicotine levels detected in those who light-up earlier
Date:12/2/2009

ow" dependant phenotype; those who smoked within the first 30 minutes of waking were considered "high." Number of cigarettes smoked per day and its association with cotinine levels varied as well.

"Not all smokers are the same and approaches to smoking reduction may need to account for individual smoking behaviors such as the intensity and frequency of puffing, cravings and physiological symptoms," said Muscat. "It is unclear why smokers who take their first puff immediately after waking have higher cotinine levels, but this may reflect a more intense pattern of smoking. We need to find out why this is."

The researchers are currently conducting follow-up studies to investigate levels of additional nicotine metabolites that will further confirm this association and help determine the impact of time to first cigarette as a novel risk factor for lung cancer.


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Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

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