Navigation Links
Increased nicotine levels detected in those who light-up earlier
Date:12/2/2009

PHILADELPHIA People who smoke their first cigarette within minutes after waking up have much higher levels of cotinine, a by-product of nicotine when processed by the body, than those who wait to smoke, regardless of the number of cigarettes smoked.

"Since cotinine levels appear to reflect the risk of lung cancer, our results suggest that smokers who smoke immediately after waking may be especially at risk for lung cancer," said researcher Joshua E. Muscat, Ph.D., M.P.H., professor of public health sciences at Penn State College of Medicine. "These people may require a more intensive intervention than other smokers to help them quit smoking on a sustained or permanent basis."

Results of this study are published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, as part of a special tobacco focus in the December issue.

Nicotine levels in the blood can be measured biochemically by the concentration of the metabolite cotinine. Muscat, along with John P. Richie, Jr., Ph.D., professor of public health sciences and pharmacology at Penn State College of Medicine, and colleagues conducted a community-based study in Westchester County, N.Y., to examine whether a behavioral aspect of nicotine dependence (the amount of time to the first cigarette after waking up) affects the physiological uptake of nicotine. This in turn may affect one's success in quitting smoking and have multiple health effects, such as lung cancer.

The study included 252 healthy black and white people who were daily cigarette smokers. Researchers examined a number of behavioral factors that are thought to measure the urge to smoke, and results showed a clear trend between lighting-up earlier and higher cotinine levels.

Cotinine levels varied from 16 ng/mL to 1180 ng/mL a 74-fold difference, according to the study. Participants who waited 30 minutes or more were categorized into the "l
'/>"/>

Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Western diet linked to increased risk of colon cancer recurrence
2. International team shows mercury concentrations in fish respond quickly to increased deposition
3. International team shows mercury concentrations in fish respond quickly to increased deposition
4. Weight gain between first and second pregnancies associated with increased odds of male second child
5. Social stress + darkness = increased anxiety
6. Baker Institute finds increased domestic production wont make US self-sufficient in natural gas
7. Research forecasts increased chances for stormy weather
8. Poultry workers at increased risk of carrying antibiotic-resistant E. coli
9. Study shows immigrant children are at increased risk of lead poisoning
10. First-ever study to link increased mortality specifically to carbon dioxide emissions
11. Environmental groups call for increased protection of coral reefs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Increased nicotine levels detected in those who light-up earlier
(Date:8/10/2015)... BOSTON and TELTOW, Germany ... SensoMotoric Instruments (SMI), a world leader in Eye ... the completion of its OEM Eye Tracking Platform for ... Eye Tracking Platform contains reference designs for seamless integration ... kiosk systems, virtual reality HMDs and augmented reality smart ...
(Date:8/6/2015)... Aug. 6, 2015 Synaptics Inc. (NASDAQ: ... interface solutions, today announced collaboration with Microsoft on ... 10. Microsoft leveraged Synaptics, deep expertise in human ... Through stringent testing, Synaptics, advanced ... with Microsoft,s Precision TouchPad (PTP) specification empowering OEMs ...
(Date:8/4/2015)... Research and ... addition of the "Digital Forensics Market ... (Computer Forensics, Network Forensics, Mobile Device Forensics, ... and Region - Global Forecast to 2020" ... By Component (Hardware, Software, and Service), Sub-Segment ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Synaptics Chosen for Human Interface Co-Development on Windows 10 2Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2
... complementary papers, researchers at the University of California, San ... importance of a relatively new class of RNA molecules. ... Nature , suggests modulation of "enhancer-directed RNAs" or ... expression in living cells, perhaps affecting the development or ...
... and NEW ORLEANS , June 3, ... America 2013 Microsoft demonstrates an FPC fingerprint touch sensor in combination ... 8. The demonstrations showcase a number of innovative online use cases ... be able to sign on to their Microsoft account, make online ...
... have long debated the core personality dimensions that ... uncover the defining personality traits for humankind,s closest ... the June 3 issue of American Journal ... universal existence of five personality dimensions in chimpanzees: ...
Cached Biology News:Enhancer RNAs alter gene expression 2Fingerprint Cards (FPC) Demonstrates Fingerprint Biometric Touch Sensor for Microsoft Windows 8.1 2Chimpanzees have 5 universal personality dimensions 2
(Date:9/3/2015)... Sept. 3, 2015 /PRNewswire/ - bioLytical Laboratories Inc., a ... its study " Sensitivity of a rapid point of ... by its affinity for HIV gp41 IgM antibodies " ...  This study highlights INSTI,s ability to detect early HIV ... at the 8 th annual International AIDS Society ...
(Date:9/3/2015)... ... , ... Park Systems announced that they will host a free ... The webinar will focus on the methods and materials for additive manufacturing – beyond ... a broad term that encompasses “addition or fusion” of materials to create an object. ...
(Date:9/2/2015)... HAMILTON, Bermuda , Sept. 2, 2015 Axovant ... on the treatment of dementia, today announced upcoming presentations at ... 4:55 PM at the Baird 2015 Healthcare Conference in ... hotel , Thursday, September 10 at 2:00 PM at ... at the Millennium Broadway Hotel & Conference Center ...
(Date:9/2/2015)... , Sep. 02, 2015 ... announced the addition of Jain PharmaBiotech,s new report ... to their offering. This report ... of sequencing technologies, and their applications. Current large ... companies developing them. Various applications of sequencing are ...
Breaking Biology Technology:bioLytical's INSTI HIV Test Detects gp41 specific IgM Antibodies 2bioLytical's INSTI HIV Test Detects gp41 specific IgM Antibodies 3Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 2Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 3Park Systems Announces Webinar on 3D Printing and Additive Manufacturing for Nano-Scientists, Researchers in Nanotechnology and Engineers 4Axovant Sciences To Present At Upcoming Investor Conferences 2Axovant Sciences To Present At Upcoming Investor Conferences 3Global DNA Sequencing Technologies Report 2015: Profiles of 130 Companies Involved in Sequencing and their 140 Collaborations 2
... Live Webcast from the Palace Hotel in San Francisco on Wednesday, ... ... 10th, SAN DIEGO, Oct. 2 Favrille, Inc. (Nasdaq:,FVRL), ... today announced that Tamara,Seymour, Chief Financial Officer, will present at the ...
... 454 Life Sciences, a Roche,company, and Perlegen Sciences, ... genetic re-sequencing in hundreds of DNA samples,collected by ... widely,prescribed class of drug. The goal of the ... can be identified and,validated to create a clinical ...
... SAFC(R), a member of the,Sigma-Aldrich(TM) Group (Nasdaq: ... to begin,construction of a new cGMP potent ... Pharma sector,s St. Louis manufacturing campus.,This addition ... requirements,that demand a combination of small molecule ...
Cached Biology Technology:New Pharmacogenomic Approach: 454 Life Sciences and Perlegen to Collaborate in Drug Response Sequencing Study 2New Pharmacogenomic Approach: 454 Life Sciences and Perlegen to Collaborate in Drug Response Sequencing Study 3SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite 2SAFC Supports Potent API Conjugate Manufacturing With New St. Louis Production Suite 3
SYBR Green Nucleic Acid Dye...
... TUNEL-based assay kit provides complete components including ... detection of DNA fragmentation in cultured cells ... in the procedure provides greater sensitivity than ... analyzed by flow cytometry. The kit works ...
... of media and other fluid sources for ... The speed of each individual pump is ... points, are exactly maintained. ,High-precision controlled ... tube types, which allows flow rates between ...
Fujifilm Pictro-Color Process for sharp, clear reproduction comparable to silver-halide photography. Photorealistic 400 dpi quality. A4 and A5 output....
Biology Products: