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In vitro antibody production enables HIV infection detection in window period -- key to safer blood
Date:7/24/2009

and SMART-plasma (plasma after the Stimmunology step) from blood donors in Kenyata hospital. Dr. Jehuda-Cohen noted that "this study, offers one of the keys to making the blood supply safer, by overcoming the problem of this protracted window period perhaps unique to certain field study sites with a high incidence/prevalence of HIV-1. This is true not only for HIV but also for other infections such as HCV, which has even a longer window period than HIV"

In summary, in-vitro enhancement of antibody production, made simple by the SMARTube, has been shown to enable the earlier detection of HIV infection. This is critical for saving lives not only via a safer blood supply but also by detection of HIV infection among pregnant women who seem to have a very long window period. "A pregnant women testing false negative for HIV will not be offered ART which could have saved her baby" said Dr. Jehuda-Cohen (a mother of seven).

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine said "The article by Mumo and colleagues may lead to a change in testing paradigms and algorithms in HIV and other infections with a diagnostic window period."


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Contact: Tamar Jehuda Cohen
tamarjc@tx.technion.ac.il
972-545-200-476
Society for Experimental Biology and Medicine
Source:Eurekalert

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