Navigation Links
In odd-looking mutant, clues about how maize plants control stem cell number
Date:9/12/2013

Cold Spring Harbor, NY -- In plants, the growth of organs such as roots, leaves and flowers depends upon the activity of meristems. These reservoir-like compartments hold stem cells, which have the ability to develop into various different cell types.

At Cold Spring Harbor Laboratory (CSHL), Professor David Jackson studies naturally occurring mutations in plants to obtain insights about how plants regulate their growth. This work has powerful implications for efforts to increase the yield of basic food crops like maize (or corn, as it is called in North America).

Today, in a paper appearing online in Nature, Jackson and colleagues present first evidence of a functional interaction between an important class of signaling molecule called a G protein, which binds receptors, and an unexpected class of cell-surface receptors.

Working backward from an odd-looking maize mutant called COMPACT PLANT2 (CT2) that develops abnormally enlarged ears a phenomenon called fasciation Jackson, Peter Bommert, Ph.D., and others found this gene to encode a G protein called Gα. Further experiments indicated an unexpected interaction between Gα and a cell-surface receptor that is a part of the CLAVATA signaling pathway, known to control stem cell activation.

The "beginning" and "end" of the CLAVATA signaling pathway were known: receptors at the cell surface are activated by a small, secreted ligand to regulate a transcription factor called WUSCHEL inside the nucleus. The Jackson lab's new research begins to fill in the gaps between these points.

Contrary to prior assumptions based on examples in mammals and yeast, the new research suggests that in plants, Gα, which acts as a signaling switch, can be activated by a G protein-coupled receptor (GPCR) that belongs to a class of cell-surface receptors that pass the cell membrane only a single time.

"The idea that Gα interacts with a single-pass trans membrane receptor called FEA2 is at odds with the dogma that in yeast and mammals, Gα interacts with GPCRs of the type that pass through the membrane seven times 7TM receptors. Further research should indicate whether this is true not only in maize but generally in plants," Jackson says.


'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Related biology news :

1. Researchers look to relatives for clues in quest to develop sources of bioenergy
2. Relative reference: Foxtail millet offers clues for assembling the switchgrass genome
3. Higher pain tolerance in athletes may hold clues for pain management
4. Clues to nervous system evolution found in nerve-less sponge
5. Preserved frogs hold clues to deadly pathogen
6. Remote Siberian lake holds clues to Arctic -- and Antarctic -- climate change
7. Highlighting molecular clues to the link between childhood maltreatment and later suicide
8. Hunting for autisms chemical clues
9. Salt cress genome yields new clues to salt tolerance
10. Gecko feet hold clues to creating bandages that stick when wet
11. A mechanism providing clues for research into pancreatic diabetes is described
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 /PRNewswire/ ... product subsidiary of Infosys (NYSE: INFY ), and ... global partnership that will provide end customers with ... banking and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... area for financial services, but it also plays a fundamental ...
(Date:4/15/2016)...  A new partnership announced today will help ... in a fraction of the time it takes ... life insurance policies to consumers without requiring inconvenient ... Diagnostics, rapid testing (A1C, Cotinine and HIV) and ... weight, pulse, BMI, and activity data) available at ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys has ... CEO, Barrett Bready , M.D., who returned to ... the original technical leadership team, including Chief Technology Officer, ... Product Development, Steve Nurnberg and Vice President of Software ... the company. Dr. Bready served as CEO ...
Breaking Biology News(10 mins):
(Date:5/27/2016)... -- At present, the Biotech sphere is in ... that volatility is what makes this industry interesting to consider. ... Corp. (NASDAQ: SNTA ), CTI BioPharma Corp. (NASDAQ: ... ), and Heat Biologics Inc. (NASDAQ: HTBX ). ... for these stocks at: http://www.activewallst.com/register/ ...
(Date:5/26/2016)... ... 2016 , ... After several promising treatments in Panama using ... of Knowledge in Panama, a 6 year-old Duchenne’s muscular dystrophy patient received his ... following FDA approval of a second application for a single patient, investigational new ...
(Date:5/25/2016)... ... May 25, 2016 , ... The Ankle Plating ... options designed to address fractures of the distal tibia and fibula. This system ... Ankle Plating System 3 is composed of seven plate families that span the ...
(Date:5/25/2016)... ... ... Lady had been battling arthritis since the age of two and at the ... Hannah sought the help of Dr Jeff Christiansen of Superior Veterinary Surgical Solutions ... help with the pain of Lady’s arthritis. Dr Christiansen suggested that in conjunction with ...
Breaking Biology Technology: