Navigation Links
In a fight to the finish, Saint Louis University research aims knockout punch at hepatitis B
Date:2/4/2013

ST. LOUIS In research published in the Jan. 24 edition of PLOS Pathogens, Saint Louis University investigators together with collaborators from the University of Missouri and the University of Pittsburgh report a breakthrough in the pursuit of new hepatitis B drugs that could help cure the virus. Researchers were able to measure and then block a previously unstudied enzyme to stop the virus from replicating, taking advantage of known similarities with another major pathogen, HIV.

John Tavis, Ph.D., study author and professor of molecular microbiology and immunology at SLU, says the finding may lead to drugs which, in combination with existing medications, could suppress the virus far enough to cure patients.

"Hepatitis B is the major cause of liver failure and liver cancer worldwide," Tavis said. "This would have an extremely positive effect on liver disease and liver cancer rates.

"If we can cure hepatitis B, we can eliminate the majority of liver cancer cases. This research is a step toward achieving that goal."

World health experts estimate that more than 350 million people are chronically infected with the hepatitis B virus. Several drugs are able to treat symptoms successfully, though they are not able to cure many patients. Of those infected with hepatitis B virus, up to 1.2 million die from liver failure and liver cancer each year.

A person who is infected with hepatitis B virus can have up to a billion viral copies per drop of blood. To cure a patient, a drug needs to reduce those levels to zero.

Not Quite a Cure

While existing medications are very powerful, they cannot quite deliver the knockout punch to hepatitis B. The drugs approved to treat the virus can reduce its numbers, make symptoms disappear for years and push it to the brink of extinction. But for most people, the medications can't kill the virus completely. And, as long as any virus remains, it can multiply and gr
'/>"/>

Contact: Carrie Bebermeyer
bebermcl@slu.edu
314-977-8015
Saint Louis University
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. UC research: Tracking Lake Erie water snake in fight against invasive fish
2. Young researcher taking fight against global killer to the next level in Vietnam
3. Evolving to fight epidemics: Weakness can be an advantage
4. Preventing home invasions means fighting side-by-side for coral-dwelling crabs and shrimp
5. Study shows botanical formula fights prostate cancer
6. Buy coal? New analysis shows purchasing fossil fuel deposits best way to fight climate change
7. Study finds cancer-fighting goodness in cholesterol
8. Trial launched into curry chemicals cancer-fighting properties
9. Canadian girl, 16, invents disease-fighting, anti-aging compound using tree particles
10. Biosensor illuminates compounds to aid fight against TB
11. Fighting bacterias strength in numbers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal genetics company, ... differences in genetic ancestry of individuals from across ... arrived more than four hundred years ago, the ... for peoples from different continents. This study illuminates how American ...
(Date:12/17/2014)... FORT BELVOIR, Va. , Dec. 15, 2014 ... make it easier to detect and prevent counterfeit microcircuits ... the agency started performing an in-house microcircuit anti-counterfeit initiative ... of purchased microcircuits while increasing their reliability throughout the ...
(Date:12/17/2014)... , Dec. 16, 2014 Research and Markets ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in this market ... applications. Chemical sensors help in recording of patient data ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... Elsevier, a world-leading provider of scientific, technical and medical ... launch of the new open access journal Photoacoustics ... is to publish original research and review contributions within ... thermoacoustics. Research in this area exploits optically and electromagnetically ...
... the University of Copenhagen, Herlev Hospital and Rigshospitalet have identified ... lipoprotein in the blood. In the long term, the research ... findings have just been published in the Journal of ... (AS) in which the opening of the aortic valve ...
... collaboration will enable university researchers to harness the ... all fields of science and discovery. This ambitious ... of California, Berkeley and the University of Washington, ... campuses and other partners pursuing similar data-intensive science ...
Cached Biology News:Elsevier launches new open access journal: Photoacoustics 2Danish researchers predict risk of valvular heart disease 2Bold new partnership launches to harness potential of data scientists and big data 2Bold new partnership launches to harness potential of data scientists and big data 3Bold new partnership launches to harness potential of data scientists and big data 4
(Date:1/22/2015)... 2015 Selexis SA, a serial innovation ... Banks (RCBs) used for drug discovery to commercial manufacturing, ... include Next-Generation Sequencing (NGS) data packages. The ... manufacturing by ensuring the integrity of the gene, validation ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... has been honored for its commitment to sustainability with inclusion ... Varian is the highest ranked healthcare equipment company among the ... during the World Economic Forum at Davos, Switzerland ...
(Date:12/24/2014)... Md. , Dec. 24, 2014  United Therapeutics Corporation ... Inc. (NYSE: MDT ) has submitted a ... Administration (FDA) for the use of Medtronic,s SynchroMed ® ... developed catheter) for use with United Therapeutics, Remodulin ® ...
(Date:12/24/2014)... “Preparative & Process Chromatography Market by ... Solvents, Buffers, Valves, Guages, Seals), Accessories, Services, End ... to 2019” provides a detailed overview of the ... and strategies impacting the preparative and process chromatography ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Varian Honored Among World's 100 Most Sustainable Corporations 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4
... producing tech-savvy workers and managers for Wisconsins knowledge-based ... It will require partnerships between business, education and ... the K-through-gray learning spectrum. , ,The latest example ... by UW-Stout to streamline transfer of credits for ...
... health care software and services company, announced Tuesday the ... The updated product includes integration with FUSION PACS, allowing ... to run from a single, unified end-user desktop application. ... improvements for the radiologist and technologist by eliminating the ...
... to reexamine the federal policy on stem cell research. ... of this debate, because our state is the birthplace of ... Jamie Thomson at the University of Wisconsin-Madison announced that ... isolated stem cells from human embryos and grown them in ...
Cached Biology Technology:Higher ed cooperation will produce more skilled workers for Wisconsin 2Higher ed cooperation will produce more skilled workers for Wisconsin 3Merge eFilm announces release of FUSION RIS version 2.5 2Gov. Doyle comments on unlocking the power of power of stem cell research 2Gov. Doyle comments on unlocking the power of power of stem cell research 3
PTFE/red rubber septum silver aluminum seal ,11 mm seal diam. ...
... enzyme that catalyzes the conversion,of starch ... maltotriose and,dextrins. The level of a-amylase ... are of clinical importance,1-3 while plant ... industry.4, The EnzChek Amylase Assay Kit ...
Rat monoclonal [20d5] to NKG2A + C+ E ( Abpromise for all tested applications). Antigen: Tissue / cell preparation (Mouse): CHO transfected cells expressing the B6 allele of NKG2A. Entrez Gen...
... FL is equipped with ... measurement technologies that complement ... advanced features of Fluoroskan ... Fluoroskan Ascent FL provides ...
Biology Products: