Navigation Links
Impulsive versus controlled men: Disinhibited brains and disinhibited behavior
Date:11/3/2011

York, November 3, 2011 Impulsive individuals tend to display aggressive behavior and have challenges ranging from drug and alcohol abuse, to problem gambling and difficult relationships. They are less able to adapt to different social situations. Impulsivity is also a common feature of psychiatric disorders. New research in Biological Psychiatry shows that people may react this way, in part, because they have lower levels of GABA (gamma-aminobutyric acid), the most important inhibitory neurotransmitter, in a specific part of their brain involved in regulating self-control.

"Advances in brain imaging techniques mean we are able to investigate different and specific areas of the human brain and see how they regulate people's behavior," explained Dr. Frederic Boy, who led the research. "What is clear is that the way people behave results from a complex interaction between a number of genetic, social and environmental factors."

The scientists studied males with no history of psychiatric disorders or substance dependence, who completed a questionnaire which helped assess different aspects of impulsivity, an important component of self-control. They underwent a specialized magnetic resonance spectroscopy brain scan, an imaging technique that allows measurement of the amount of GABA in small regions of the brain.

The team found that men with more GABA in their dorsolateral prefrontal cortex had lower scores in one aspect of impulsivity called the "feeling of urgency", the tendency to act rashly in response to distress or other strong emotions and urges. Inversely, men with lower GABA tended to have higher urgency ratings. These findings add to evidence that "low GABA may be a risk factor for cortical dysfunction across a number of disorders, as depression and panic disorder are associated with low cortical GABA," commented Dr. John Krystal, Editor of Biological Psychiatry, which published the research. These findings may also hol
'/>"/>

Contact: Donna Santaromita
d.santaromita@elsevier.com
212-633-3962
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Study shows value of sexual reproduction versus asexual reproduction
2. Caltech: Gain and loss in optimistic versus pessimistic brains
3. Epigenetic memory key to nature versus nurture
4. IVF treatment and multiple births: Free-market patient rights versus government regulation
5. Type 2 diabetes: Intensive versus conventional blood glucose control -- no clear picture
6. Can genetic information be controlled by light?
7. Motor nerve targeting to limb muscles is controlled by ephrin proteins
8. Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial
9. Major international study challenges notions of how genes are controlled in mammals
10. Study may aid efforts to prevent uncontrolled cell division in cancer
11. Step forward for nanotechnology: Controlled movement of molecules
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... is available in German . ... the protection money demanded of him, he can expect his ... however, as fear of the consequences is enough to make ... parasitic birds, which lay their eggs in other birds, nests. ... brood parasites take their revenge by destroying the entire nest. ...
(Date:4/17/2014)... the Amazon help create tinderbox conditions for wildfires ... forest loss during drought years, according to a ... in the Amazon could reach a "tipping point" ... to large-scale loss of trees, making recovery more ... Penn State. , "We documented one of the ...
(Date:4/17/2014)... are implicated in many serious conditions such as heart ... target for drug therapies. Unfortunately, there is still much ... research provides fresh and unexpected insight into the structure ... - β-subunit molecules - which are responsible for ,fine-tuning, ... in the most recent edition of the Journal ...
Breaking Biology News(10 mins):Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3Structure of sodium channels different than previously believed 2
... CORVALLIS, Ore. - Penguins that died 44,000 years ago ... challenge the accuracy of traditional genetic aging measurements, and ... of many specimens by 200 to 600 percent. ... DNA testing to be 100,000 years old may actually ...
... The war between the sexes has been fought on ... the animal kingdom is replete with species involved in ... Eppley and colleagues at Portland State University published in ... Botany ( www.amjbot.org/cgi/content/full/96/11/1967 ) demonstrates that certain plants, ...
... in Spanish . , Figures are impressive and, ... century: according to data from the United Nations through the UN.GIFT ... 161 countries are reported to be affected by human trafficking by ... victims are between 18 and 24 years of age but an ...
Cached Biology News:Ancient penguin DNA raises doubts about accuracy of genetic dating techniques 2In the war between the sexes, the one with the closest fungal relationship wins 2Geneticists coordinate action to fight against traffic in human beings 2Geneticists coordinate action to fight against traffic in human beings 3
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how latent ... viruses is the Epstein Barr Virus (EBV), and one of ... a chronic inflammatory disease that destroys the body’s joints. As ... have high concentrations of EBV DNA in their bodies (1). ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 2013 was ... Scottsdale’s Brain State Technologies®. They saw continued independent research ... Center who were awarded a $1 million grant from ... in “Brain and Behavior” a peer reviewed journal, Amy ...
(Date:1/15/2014)... AudioNotch is the internet's leading provider of ... of tinnitus. Patients listen to sound therapy that is ... of weeks to months, their tinnitus volume decreases. , AudioNotch ... Music and Notched White Noise. Now, AudioNotch is pleased to ...
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 ... Almshouse Road, Warrington, Pa. , Details: The Hepatitis ... finding a cure for hepatitis B and improving the quality ... Crystal Ball on Friday, April 11 at Warrington Country Club ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... , LUMBY, BC, July 2 /PRNewswire-FirstCall/ - avVaa ... a global biotechnology company, manufacturer and distributor of ... products, announced the engagement of Koeppel Direct to ... Campbell-Farley, President/COO of avVaa World Health Care is ...
... July 2 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, ... enrolment has been completed in the Phase II component ... with paclitaxel/carboplatin for patients with advanced cancers. The principal ... The Institute of Cancer Research, London, England, and Dr. ...
... analysis technique that identifies and removes systematic bias, ... lead to more precise and reliable measurement of ... applications. Known as sequential profile adjustment by ... amount of experimental data required to make conclusions, ...
Cached Biology Technology:avVaa World Health Care Products, Inc. Announces Engagement of Koeppel Direct for their DRTV-Direct Response Television Media Buying Campaign 2Oncolytics Biotech(R) Inc. Completes Patient Enrolment in U.K. Combination REOLYSIN(R) and Paclitaxel/Carboplatin Head and Neck Cancer Trial 2New statistical technique improves precision of nanotechnology data 2New statistical technique improves precision of nanotechnology data 3New statistical technique improves precision of nanotechnology data 4