Important new hair-loss gene discovered(nter) and Privatdozent Dr. Roland Kruse ...)

Date:10/12/2008

nter) and Privatdozent Dr. Roland Kruse (Department of Dermatology, University Clinic Dsseldorf). Over a period of years, the scientists had collected blood samples from affected males all over Germany. As part of their study, they have been able to confirm their findings through additional sufferers in Australia. The Australian research team is headed by Nicholas Martin (Queensland Institute of Medical Research, Brisbane).

If the father is bald, the son is also at risk

The results reveal that more than one gene is involved in the development of male hair-loss. These results also throw interesting light on the inheritance of baldness in that hitherto the only known risk gene for the androgen receptor lay on the X-chromosome, and was thus inherited from the mother which accounts for the fact that in the case of hair-loss men often take after their maternal grandfathers. However, the newly discovered gene lies on chromosome 20, and can be inherited from both the mother and the father. "This helps to provide an explanation for the similarity between father and son", declares Professor Nthen.

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Contact: Prof. Dr. Markus M. Nthen markus.noethen@uni-bonn.de 49-228-287-22347 University of Bonn Source:Eurekalert

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