Navigation Links
Implants mimic infection to rally immune system against tumors
Date:1/22/2009

dritic cells then report to nearby lymph nodes, where they activate the immune system's T cells to hunt down and kill tumor cells throughout the body.

"Much as an immune response to a bacterium or virus generates long-term resistance to that particular strain, we anticipate our materials will generate permanent and body-wide resistance against cancerous cells, providing durable protection against relapse," says Mooney, a core member of the recently established Wyss Institute for Biologically Inspired Engineering at Harvard.

The implants could also be loaded with bacterial or viral antigens to safeguard against an array of infectious diseases. They could even redirect the immune system to combat autoimmune diseases such as type 1 diabetes, which occurs when immune cells attack insulin-producing pancreatic cells.

"This study demonstrated a powerful new application for polymeric biomaterials that may potentially be used to treat a variety of diseases by programming or reprogramming host cells," Mooney and his co-authors write in Nature Materials. "The system may be applicable to other situations in which it is desirable to promote a destructive immune response (for example, eradicate infectious diseases) or to promote tolerance (for example, subvert autoimmune disease)."


'/>"/>

Contact: Steve Bradt
steve_bradt@harvard.edu
617-496-8070
Harvard University
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. TECNALIA investigates advanced biomaterials to make more reliable and hardwearing medical implants
2. Researchers design artificial cells that could power medical implants
3. Layered approach may yield stronger, more successful bone implants
4. Scientists create tough ceramic that mimics mother of pearl
5. Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research
6. Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
7. Genetic variant mimics effect of heart failure medications
8. Researchers mimic bacteria to produce magnetic nanoparticles
9. Zoologists challenge longstanding theory that eyespots mimic the eyes of predators enemies
10. Team of chemists receives $5 million grant to develop enzyme mimics
11. Researchers identify potential new weapon in battle against HIV infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2013)... modifications, which alter the way genes function without ... detected in the blood of pregnant women during ... foretell depression in the weeks after giving birth, ... debilitating. , The findings of the small study ... the journal Molecular Psychiatry . , "Postpartum ...
(Date:5/20/2013)... New research suggests that a compound abundant in the ... death. , By altering a very specific step ... into normal cells that die as scheduled. , One ... process that would cause them to die on a ... study in cells, led by Ohio State University researchers, ...
(Date:5/19/2013)... novel study reports that white men and women of ... (hallux valgus) and lesser toe deformities, including hammer or ... to estimate the heritability of foot disorders in humansappear ... published by Wiley on behalf of the American College ... as many as 60% of older adults have foot ...
Breaking Biology News(10 mins):Genetic predictors of postpartum depression uncovered by Hopkins researchers 2Genetic predictors of postpartum depression uncovered by Hopkins researchers 3The compound in the Mediterranean diet that makes cancer cells 'mortal' 2The compound in the Mediterranean diet that makes cancer cells 'mortal' 3Blame your parents for bunion woes 2
... American Geological Institute (AGI), in conjunction with its ... Needs for the Twenty First Century: The Role ... directions for the next President, his administration, federal ... identifies seven national issues and the role geosciences ...
... spiders are voracious predators and consume a wide range of ... have been proposed for why females eat males before or ... University in Ohio found, in a study published in the ... answer may be simpler than previously thought. Males are more ...
... A Florida State University researcher who uses high-powered computers ... mechanism that gives scientists a better understanding of how ... understanding eventually could lead to the development of new ... an assistant professor in FSU,s Department of Chemistry and ...
Cached Biology News:In spiders, size matters: Small males are more often meals 2Computational biochemist uncovers a molecular clue to evolution 2Computational biochemist uncovers a molecular clue to evolution 3
(Date:5/21/2013)... a new study led by George Washington University ... nucleation of ice in small droplets is strongly ... at the nanoscale. The formation of ice at ... question whose answer also has important implications for ... crystallization of ice from supercooled water is generally ...
(Date:5/21/2013)... Raleigh, NC (PRWEB) May 21, 2013 ... and financial services company for clinical trials, announced ... Aggregate Spend Solutions, LLC. Clinverse’s ClinPay® FLS ... automated investigator payment process. SpendMD ™, ... only complete solution for tracking and reporting transfer ...
(Date:5/21/2013)... Many have long discussed the link between mental ... from Clinical Psychiatry.com readdressed the topic of ... suggested using hypnotherapy and other mental health ... that cause acne. , Doctors in the article mentioned ... stress causes changes in the skin that have been ...
(Date:5/21/2013)... May 21, 2013  Personal Genome Diagnostics Inc. ... proprietary methodologies and expertise in genomic analysis of ... in collaboration with Blueprint Medicines.  PGDx is an ... genomic alterations in tumors, and Blueprint Medicines is ... for a genetically defined patient population. ...
Breaking Biology Technology:Study led by GW professor provides better understanding of water's freezing behavior at nanoscale 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3Adult Acne Treatment, Probiotic Action Explains How Hypnotherapy and Probiotics May Cure Various Skin Conditions 2Personal Genome Diagnostics And Blueprint Medicines Form Collaboration to Identify Novel Kinase Targets 2Personal Genome Diagnostics And Blueprint Medicines Form Collaboration to Identify Novel Kinase Targets 3
... GlaxoSmithKline CEO, described the pharmaceutical group,s results as,"robust" in a ... GSK also announced that it will cease ... goals. , Describing 2008 as a ... make very clear what it would take to really make ...
... BETHESDA, Md., Feb. 5 Micromet, Inc. (Nasdaq: MITI ), ... at the BIO CEO and Investor Conference at the Waldorf-Astoria in New ... presentation will be available on the company,s website at www.micromet-inc.com ., ... Date: Tuesday, February 10, 2009, ...
... type 2 diabetes enters clinical developmentCARLSBAD, Calif., Feb. 5 ... announced today it has initiated a Phase 1 study ... of sodium dependent glucose co-transporter type 2 (SGLT2). ... in the kidney. Decreasing SGLT2 levels promotes glucose ...
Cached Biology Technology:Micromet to Present at the BIO CEO and Investor Conference on February 10, 2009 2Micromet to Present at the BIO CEO and Investor Conference on February 10, 2009 3Micromet to Present at the BIO CEO and Investor Conference on February 10, 2009 4Isis Initiates Phase 1 Clinical Trial of SGLT2 Antisense Drug 2Isis Initiates Phase 1 Clinical Trial of SGLT2 Antisense Drug 3Isis Initiates Phase 1 Clinical Trial of SGLT2 Antisense Drug 4
Rabbit polyclonal to NMDAR1 e/f/g/h ( Abpromise for all tested applications)....
Biotin anti-mouse Ly-49C/F/I/H...
Monoclonal Antibody to GLP Immunogen: Ni-NTA purified truncated recombinant GLP expressed in E. Coli strain BL21 (DE3)...
... Vitro Transcription Kits synthesize RNA probes with ... cpm/g. High specific activity, single-stranded RNA ... in situ hybridization, and blot hybridizations. MAXIscript ... synthesis of modest amounts of unlabeled RNA ...
Biology Products: