Navigation Links
Implanted Neurons become Part of the Brain
Date:8/4/2014

Scientists at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have grafted neurons reprogrammed from skin cells into the brains of mice for the first time with long-term stability. Six months after implantation, the neurons had become fully functionally integrated into the brain. This successful, because lastingly stable, implantation of neurons raises hope for future therapies that will replace sick neurons with healthy ones in the brains of Parkinson's disease patients, for example. The Luxembourg researchers published their results in the current issue of Stem Cell Reports.

The LCSB research group around Prof. Dr. Jens Schwamborn and Kathrin Hemmer is working continuously to bring cell replacement therapy to maturity as a treatment for neurodegenerative diseases. Sick and dead neurons in the brain can be replaced with new cells. This could one day cure disorders such as Parkinson's disease. The path towards successful therapy in humans, however, is long. "Successes in human therapy are still a long way off, but I am sure successful cell replacement therapies will exist in future. Our research results have taken us a step further in this direction," declares stem cell researcher Prof. Schwamborn, who heads a group of 15 scientists at LCSB.

In their latest tests, the research group and colleagues from the Max Planck Institute and the University Hospital Mnster and the University of Bielefeld succeeded in creating stable nerve tissue in the brain from neurons that had been reprogrammed from skin cells. The stem cell researchers' technique of producing neurons, or more specifically induced neuronal stem cells (iNSC), in a petri dish from the host's own skin cells considerably improves the compatibility of the implanted cells. The treated mice showed no adverse side effects even six months after implantation into the hippocampus and cortex regions of the brain. In fact it was quite the opposite the implanted
'/>"/>

Contact: Britta Schlüter
britta.schlueter@uni.lu
352-466-644-6563
University of Luxembourg
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Implanted infection prevention
2. Nanotube-based sensors can be implanted under the skin for a year
3. Wireless, implanted sensor broadens range of brain research
4. Intranasal nerve growth factor repairs injured spinal cord neurons
5. Zhichan decoction increases dopaminergic neurons from transplanted NSCs in PD
6. Chrysophanol attenuates injury to hippocampal neurons in lead-exposed neonatal mice
7. Protective effect of α-synuclein knockdown on dopaminergic neurons
8. Neuropeptide Y protects cerebral cortical neurons
9. Thyroid hormone protects hippocampal cholinergic neurons in normal aged animals
10. Watching individual neurons respond to magnetic therapy
11. Neurons get their neighbors to take out their trash
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Implanted Neurons become Part of the Brain
(Date:8/5/2015)... -- According to a new market research ... Vertical (BFSI, Airport, IT & Telecom, Utilities, Education, Defense ... 2020", published by MarketsandMarkets, defines and segments the Physical ... The global PIAM Market is estimated to grow from ... at a CAGR of 14.9 % from 2014 to ...
(Date:8/5/2015)... 2015 The biosensors market is proving highly ... into newer sectors, and development of devices resulting in ... has seen the entry of multiple participants each year ... (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ) ... the Global Biosensors Market ( http://www.frost.com/nee9 ), finds ...
(Date:8/4/2015)... AMRI ) today reported financial and operating results for the second ... Second quarter contract revenue of $ 85.2 million, ... margins of 26 % , Second quarter ... from royalties in the current quarter , Operating ... pleased to present another strong financial quarter, with all our divisions ...
Breaking Biology News(10 mins):Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4AMRI Announces Second Quarter 2015 Results 2AMRI Announces Second Quarter 2015 Results 3AMRI Announces Second Quarter 2015 Results 4AMRI Announces Second Quarter 2015 Results 5AMRI Announces Second Quarter 2015 Results 6AMRI Announces Second Quarter 2015 Results 7AMRI Announces Second Quarter 2015 Results 8AMRI Announces Second Quarter 2015 Results 9AMRI Announces Second Quarter 2015 Results 10AMRI Announces Second Quarter 2015 Results 11AMRI Announces Second Quarter 2015 Results 12AMRI Announces Second Quarter 2015 Results 13AMRI Announces Second Quarter 2015 Results 14AMRI Announces Second Quarter 2015 Results 15AMRI Announces Second Quarter 2015 Results 16AMRI Announces Second Quarter 2015 Results 17AMRI Announces Second Quarter 2015 Results 18AMRI Announces Second Quarter 2015 Results 19AMRI Announces Second Quarter 2015 Results 20AMRI Announces Second Quarter 2015 Results 21AMRI Announces Second Quarter 2015 Results 22AMRI Announces Second Quarter 2015 Results 23AMRI Announces Second Quarter 2015 Results 24
... professionals send genes and healthy cells on their way ... repair tissue damage to arteries. But do they reach ... have developed a highly sensitive measuring method with which ... magnetic particles which are situated on the planted gene ...
... a protein is determined both by its structure and ... proteins had to be isolated for analyzing them. An ... University, and the Frankfurt Institute for Advanced Studies (FIAS) ... a protein in its natural environment, the living cell. ...
... 4 Innerscope Research(R), a revolutionary biometric media ... today the appointment of Andre Marquis as Senior ... will be responsible for expanding Innerscope,s offering into ... years experience driving innovative digital initiatives for start-ups ...
Cached Biology News:Protein structure determined in living cells 2Innerscope Research(R) Appoints Digital Leader, Andre Marquis, as Senior Vice President of Sales and Marketing 2
(Date:9/2/2015)... 2015 Research and Markets ( ... Jain PharmaBiotech,s new report "Nanobiotechnology Applications, ... An increasing use of ... is anticipated. Nanotechnology will be applied at ... formulations for optimal delivery to diagnostic applications ...
(Date:9/2/2015)... DUBLIN , Sep. 02, 2015 ... ) has announced the addition of Jain PharmaBiotech,s ... Markets and Companies" to their offering. ... markets based on technologies and applications. The report ... basis for estimation of markets. Technologies include array ...
(Date:9/2/2015)... , Sep. 02, 2015 ... the addition of Jain PharmaBiotech,s new report "Gene ... offering. The markets for gene therapy are ... gene therapy product and it is marketed in ... are estimated for the years 2014-2024. The estimates are ...
(Date:9/2/2015)... ... September 02, 2015 , ... Drug companies increasingly are ... BCC Research reveals in its new report that the U.S. will generate the ... and generates the most market demand. , BCC Research examines plant-derived drugs ...
Breaking Biology Technology:Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 2Global Nanobiotechnology Applications, Markets and Companies Report 2015-2024 3Global Biochips and Microarrays Technologies, Markets and Companies Report 2015 with Market Size in 2014 and Projected Value for the Years 2019 and 2024 2Global Gene Therapy Market Study 2015-2024 - Technologies, Markets and Companies Analysis 2Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 2Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 3
... Madison,Wis. - Esker Software , ... headquarters in Madison, received a U.S. patent for ... mechanism for enabling content-based document delivery. , ,DeliveryWare ... to determine formatting, conversion and routing actions as ...
... Wis. Information technology professionals in Wisconsin announced ... Association of Wisconsin, a forum for information exchange ... than $14B in revenue and hires more than 55,000 ... 30 founding members, of which approximately a third are ...
... that the role of IT professional is one of diplomat between ... head of urgent communiqus and hushed conversations, exotic locales (like the ... of tense situations that could boil over into real conflict at ... deal of flexibility is the order of the day. , ...
Cached Biology Technology:Statewide IT association will address IT issues and priorities 2Statewide IT association will address IT issues and priorities 3IT is the New Foreign Service 2IT is the New Foreign Service 3
... The Holten MaxiSafe 2010 Class II ... ergonomical working condition of comfort while ... efficiency and performance.,Refined operator, environment and ... both exhausted and recirculated air.,Bottom filters ...
... of Class II Biological Safety Cabinets ... to the world's highest safety standards. ... cabinets cannot be adjusted out of ... noise and arm rest ensure safety ...
... designed for paramagnetic bead precipitation from standard ... plates with no additional accessories. The stand ... standard SBS 96-well microplate footprint. The use ... easy and fast (as little as 30 ...
... with circular clear acrylic chamber for complete ... Oven features microprocessor operation for precise mixing ... unit., Carousel rotates at 11 rpm; ... removable , Bottle Capacity - four ...
Biology Products: