Navigation Links
Impaired cell division leads to neuronal disorder
Date:1/31/2014

IL protein," explains Christian Arquint, the first author of this publication. In the absence of the KEN-Box, the protein is not degraded.

Absence of the KEN-Box causes microcephaly

In some patients with microcephaly, a neuronal disorder that leads to a reduced number of nerve cells being produced and, therefore, a smaller brain, the KEN-box is lacking from the STIL protein. The scientists were thus able to demonstrate a tantalizing connection between the absence of this particular amino acid signal and an illness. "When during our investigations of cell division and centrosome duplication we came across a connection to the disorder microcephaly, we were particularly pleased, as this helps us to better understand how this disorder develops," says Christian Arquint.

In the future, the research group led by Erich Nigg plans to uncover other connections between errors of cell division and the illness microcephaly. They also want to focus on the investigation of other proteins that play important roles in the process of cell division, in particular those involved in centrosome duplication.


'/>"/>

Contact: Heike Sacher
heike.sacher@unibas.ch
University of Basel
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Research breakthrough: Impaired autophagy associated with age-related macular degeneration
2. People with impaired glucose tolerance can show cognitive dysfunction
3. Psychopaths have an impaired sense of smell
4. Impaired recovery of Atlantic cod -- forage fish or other factors?
5. Researchers identify key components linking circadian rhythms and cell division cycles
6. High-resolution 3-D imaging draws new picture of Golgis whereabouts during cell division
7. SourceMedical Announces Hiring of Clinical Expert for ASC Division
8. Division of labor in the test tube
9. Discovery of cell division master controller may improve understanding and treatment of cancer
10. New insight into double-protected dance of cell division
11. Molecular forces are key to proper cell division
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Impaired cell division leads to neuronal disorder
(Date:9/30/2014)... 30, 2014) People who suffer from asthma may ... control their asthma besides properly taking medications and avoiding ... in the Annals of Allergy, Asthma and Immunology ... Allergy, Asthma and Immunology (ACAAI), asthma sufferers can learn ... The woman described in the Annals article improved her ...
(Date:9/29/2014)... Monday, September 29: Between 1970 and 2010 populations ... the globe dropped 52 percent, says the 2014 ... Fund (WWF). This biodiversity loss occurs disproportionately in ... of high-income countries. , In addition to the ... point to other warning signs about the overall ...
(Date:9/29/2014)... In order to support the world,s needs ... polymers and more, new and more efficient catalytic ... of researchers, including several from Wayne State University, ... a new grant from the National Science Foundation. ... Design of Multicomponent Materials for Electrocatalytic Cascade Reactions," ...
Breaking Biology News(10 mins):Asthma symptoms kicking up? Check your exposure to air pollution 2Half of global wildlife lost, says new WWF report 2Wayne State research aims to develop new, more efficient catalytic materials 2
... boost our understanding of the fragile marine environment, the ... for Environment, Fisheries & Aquaculture Science (Cefas) are launching ... existing collaboration between the two institutions and establish exciting ... climate change on the marine environment will influence much ...
... science concern the behaviour of the most commonplace compound ... the mysteries are now being unravelled by the latest ... was presented at a recent conference organised by the ... and other compounds at the molecular level. , Some ...
... window into the Earths mantle, a University of Houston professor ... more complex than previously thought. Jonathan Snow, ... researchers in a North Pole expedition, resulting in a discovery ... layer that lies beneath the planets outer crust. These ...
Cached Biology News:New UEA-Cefas alliance launched 2ESF conference probes water's mysterious interactions at molecular level 2ESF conference probes water's mysterious interactions at molecular level 3Journey to the center of the earth: Discovery sheds light on mantle formation 2Journey to the center of the earth: Discovery sheds light on mantle formation 3
(Date:9/30/2014)... Applying a well-known optical phenomenon called thin-film ... has demonstrated the ability to "paint" ultra-thin coatings ... promise for making future, flexible electronic devices, creating ... next-gen rocket ships and spacecraft with extremely lightweight ... in water, it becomes iridescent, revealing a myriad ...
(Date:9/30/2014)... YORK , Sept. 30, 2014 ... and segments with highest potential revenues Do you ... updated report gives you revenue predictions for those ... For those therapies you find financial data, R&D ... analysis you get sales forecasts to 2024 at ...
(Date:9/30/2014)... Proove Biosciences , the commercial and research leader in ... test built upon research from their published P.A.I.N. Study. ... physicians with an objective way to understand theirs patient’s ... individuals. With this new test, physicians will be able ... that will affect their pain tolerance. , The P.A.I.N. ...
(Date:9/30/2014)... , September 30, 2014 ... intuitive browsing of chemistry in documents ... software solutions and consulting services for life science ... information and generate Markush structures from documents. ... organizations intellectual property, however generating and understanding Markush ...
Breaking Biology Technology:Taking thin films to the extreme 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 2Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 3Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 4Biosimilars and Follow-On Biologics: World Industry and Market Prospects 2014-2024 5Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2
... RedPrairie Corp. , the Waukesha-based manufacturer of supply chain ... a recent user conference. , ,At RedShift: 2006, the ... unveiled its E2e suite of solutions, which is described ... chain challenges faced by customers. , ,RedPrairie executive John ...
... - By several measures, these should be heady days ... manufacturing jobs were lost, the economy is back, manufacturing revenue ... there is a sense of unease linked to withering competitive ... of what their American counterparts earn, where manufacturers have a ...
... that the ownership of a patent right initially goes to ... in the workplace? The company? The inventing employee? It depends ... Is there an employment agreement signed by the employee that ... workplace to the company? , ,No? Then you must ask: ...
Cached Biology Technology:Manufacturers advised to redesign customer relations 2Manufacturers advised to redesign customer relations 3Who owns what invention in the workplace? 2
... (MOPS Buffered) has been developed specifically for ... solution. HRP Stabilizer prevents the loss ... of the antibody or protein antigen portion ... at 0.2 microns., ,Contents: Aqueous, protein-containing ...
384 Well PCR Plate Carrier for Thermo-Sealer...
... strength adhesive system which facilitates the easy removal ... either side of the frame are of differing ... has an easy release adhesive whereas the reverse, ... bond. This means that when the coverslip is ...
These 18x18 square No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick....
Biology Products: