Navigation Links
Immunological mechanisms of oncolytic adenoviral therapy
Date:1/26/2012

. This anti-tumor immune memory is thought to play a major role in preventing tumor relapse. For larger tumors, Ad5 therapy alone controls tumor growth only transiently. However, Ad5 therapy followed by treatment with agonistic anti-4-1BB (cluster differentiation 137, CD137) antibody, a potent enhancer of the specific CD8+ T cell response, resulted in complete rejection of all transplanted tumors, demonstrating that promotion of T cell responses against tumors could enhance the therapeutic effects of oncolytic adenovirus.

In summary, this study provides insight into the antitumor mechanisms of oncolytic adenovirus, in addition to their direct oncolytic effect. Meanwhile, this study proposes a new and more effective therapeutic regime for cancer treatment using a combination therapy of oncolytic adenovirus and immunotherapy.


'/>"/>
Contact: Wang Shengdian
sdwang@moon.ibp.ac.cn
0086-106-488-8493
Science in China Press
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Immunological defense mechanism leaves malaria patients vulnerable to deadly infection
2. Pitt/UPMC: Exceptional cognitive and physical health in old age leaves immunological fingerprint
3. Keystone Symposia to hold conference in Seattle on immunological mechanisms of vaccination
4. Research team discovers genes and disease mechanisms behind a common form of muscular dystrophy
5. Bone marrow-derived cells differentiate in the brain through mechanisms of plasticity
6. New leads on mechanisms that confer virulence to E.coli-type bacteria
7. Study identifies mechanisms cells use to remove bits of RNA from DNA strands
8. Milking the pigeon: extracting the mechanisms involved
9. Primary component in turmeric kicks off cancer-killing mechanisms in human saliva
10. New perspectives on sensory mechanisms
11. Novel analysis by Allen Institute sheds new light on the mechanisms of brain development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces that its Wocket® ... first week of May, 2015 and will be fulfilling ... Gino Pereira , Chief Executive Officer ... as Wocket® enters the consumer market. We would like ...
(Date:4/20/2015)... 20, 2015 The announcement comes ... Glenbeigh Records Management (GRM), Ireland,s foremost ... Bank. Having built up an impressive track record of clients ... player within the records management sector in Dubai ... is GCC staffbase and employ a further eight staff members ...
(Date:4/13/2015)... 13, 2015 According to ... Biometrics Market Forecast & Opportunities, 2020", the global biometrics ... around 14% till 2020. The biometrics market is ... implementation and review of biometric management systems. The ... products with greater efficiency, are resulting in increasing ...
Breaking Biology News(10 mins):Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2
... Health has awarded Montana State University's Center for Biofilm Engineering ... chronic wounds. , The money will allow the center ... equipment for its investigation into the role biofilms play in ... , Biofilms are bacteria that grab onto a surface, ...
... aging process is linked to DNA damage--which occurs normally as ... ways in which cells repair that damage. In the new ... use of a different mix of molecular DNA-repair mechanisms compared ... William Engels and colleagues at the University of Wisconsin and ...
... By investigating how animals can predict the timing of ... for anticipation of mealtime. This gene, called Period 2, ... The findings are reported by Urs Albrecht of the ... Louis Pasteur/CNRS and colleagues in the October 24th issue ...
Cached Biology News:Search on for treatment of slow-healing wounds 2Search on for treatment of slow-healing wounds 3Age-related changes in DNA repair illuminate the connection between age and genetic damage 2Circadian gene helps the brain predict mealtime 2
(Date:5/28/2015)... 28, 2015 Global futurist and ... to ask his audiences if they are ready ... robotics, solar cells, fuel cells, rapid health care ... battery storage technology, driverless cars, artificial intelligence masquerading ... inexpensive online education. , While the majority ...
(Date:5/27/2015)... 2015  The Companion Diagnostics Deals and Alliances ... access to the partnering deals and agreements entered ... 2014. Using these reports, dealmakers will ... activities of the past year. The report series ... alliances deals announced worldwide.The initial chapters of this ...
(Date:5/27/2015)... Fla. (PRWEB) May 27, 2015 Expanding ... dental cement manufacturer Avalon Biomed Inc. recently ... of Mokuda Dental Co. Ltd. , the largest ... inroad into the international market for Avalon Biomed, which ... Plus®, award-winning tricalcium silicate-based dental cements that have won ...
(Date:5/27/2015)... FRANCISCO, Calif. , May 27, 2015 /PRNewswire/ ... the treatment of cancer, today announced the appointments ... officer and Cynthia Ladd as senior ... CytomX, Goeltz was chief financial officer of Onyx ... as an independent consultant and legal counsel to ...
Breaking Biology Technology:Futurist Jack Uldrich to Deliver 4 Keynote Addresses in June 2Companion Diagnostics Deals and Alliances of 2014 2Dental Manufacturer Avalon Biomed Inks Major Deal with Japanese Distributor 2Dental Manufacturer Avalon Biomed Inks Major Deal with Japanese Distributor 3CytomX Expands Executive Leadership Team 2CytomX Expands Executive Leadership Team 3
... ABERDEEN PROVING GROUND, Md., Dec. 19 Dr. ... Technology for,the Edgewood Chemical Biological Center (ECBC). With ... Service (SES). Members of the SES,serve in key ... the,major link between the appointees and the federal ...
... Pfizer Study Finds Pathway,s SensiTrop(TM) Assay Is Discordant in ... HIV Tropism with Clinically Validated ... Monogram,Biosciences, Inc. (Nasdaq: MGRM ) today announced that ... reported the,results of a study that compares Monogram,s Trofile ...
... & Bioressources Inc. enters into an exclusive, distribution agreement with AZPA ... ... Zealand -, LAVAL, QC, Dec. 19 /PRNewswire-FirstCall/ ... to,announce that it has entered into an exclusive distribution agreement with,AZPA ...
Cached Biology Technology:Dr. Joseph L. Corriveau Appointed Director of Research and Technology 2Study Reaffirms Superiority of Trofile(TM) Assay 2Study Reaffirms Superiority of Trofile(TM) Assay 3Study Reaffirms Superiority of Trofile(TM) Assay 4Study Reaffirms Superiority of Trofile(TM) Assay 5Study Reaffirms Superiority of Trofile(TM) Assay 6Nationwide product launch of NKO(R) planned for February 2008 in Australia and New Zealand 2Nationwide product launch of NKO(R) planned for February 2008 in Australia and New Zealand 3
... Cary 50 Microplate Reader accessory ... per analysis by extending the ... award-winning Cary 50 instruments. Use ... 384 samples in microlitre volumes, ...
IMAGEQUANT 300 WKSTN, 1 EA. Category: ImageQuant CCD Imagers....
PAb to Hu-IFN-Alpha/Beta R2 [(IFNAR2) CD118], Rabbit Serum, neutralizing Binds to but does not neutralize human interferon alpha/beta receptor...
IMAGEQUANT 400 IQTL, 1 EA. Category: ImageQuant CCD Imagers....
Biology Products: