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Immune system protein accurate predictor of survival in pediatric septic shock
Date:8/1/2008

asurements and other patient information from two separate databases that included a total of 332 septic shock patients younger than 10 years old. Using statistical analyses of IL-8 levels obtained within 24 hours of hospital admissions, the researchers projected that a threshold of 220 pg/ml blood serum would have sensitivity for predicting rates of deaths in patients 75 percent of the time. The subsequent analyses, conducted separately on patient data from both databases, revealed a much higher validation of 95 percent accuracy when using an IL-8 level of 220 pg/ml or less to predict septic shock survivability at 28 days following hospital admission.


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Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center
Source:Eurekalert

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