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Immune-response genes affecting breast tumor eradication
Date:5/3/2012

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"The role of agents that modulate immune response in breast cancer should be studied, and in these trials patients should be optimally stratified based on their immune response," the researcher added. "Moreover, future studies should investigate whether the efficacy of anti-HER2 agents in HER2-positive early breast cancer patients is also associated with tumor immune response."

Commenting on this study, which he was not involved in, Dr Angelo Di Leo from the Hospital of Prato, Italy, former IMPAKT Chair, noted: "This study highlights the importance of the immune response of the patient as a major factor that can substantially impact treatment efficacy. It is quite clear that response to a given anti-cancer treatment may vary from one patient to another based also on the ability of the patient's immune system to aggress the tumor. This and other recently published studies pave the way to the development of a new generation of cancer drugs that can stimulate the immune response of the patient and make it more efficient in aggressing the tumor."


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Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

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