Navigation Links
Immune cells promote blood vessel formation in mouse endometriosis
Date:10/18/2007

support endothelial cells that build the new blood vessels.

"We believe that targeting dendritic cells may prove to be a promising strategy for treating conditions dependent on angiogenesis, such as endometriosis and cancer," says Fainaru. But first, the team must demonstrate that dendritic cells are essentialthat without these cells in mice, new blood vessels do not form.

"Our next step would be to look for specific dendritic cell inhibitors that could have the potential to block angiogenesis in these conditions," says Fainaru.

The team hopes to develop cell-specific therapy for angiogenesis-dependent diseases that will be more effective and less toxic than current treatments. Currently, the most effective treatment for endometriosis is surgically removing the lesions, but this does not prevent them from growing backas large and symptomatic as before. If dendritic cells are indeed ringmasters and not sideliners in new blood vessel growth, locally knocking them out just after an initial surgery, or altering them in some way, could render the lesions tiny and harmless.

Similarly, potential dendritic-cell inhibitors, when added to other agents that stop new blood vessels from forming, could enhance doctors ability to choke off growing tumors, Fainaru adds.


'/>"/>

Contact: Bess Andrews
elizabeth.andrews@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Source:Eurekalert

Page: 1 2

Related biology news :

1. Fox Chase Cancer Center scientists identify immune-system mutation
2. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
3. Genetically modified natural killer immune cells attack, kill leukemia cells
4. Studies reveal methods viruses use to sidestep immune system
5. Jumping gene helps explain immune systems abilities
6. Scientists solve structure of key protein in innate immune response
7. Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
8. NYU study reveals how brains immune system fights viral encephalitis
9. Chemists identify immune system mechanism for methamphetamine binges
10. Multi-purpose protein regulates new protein synthesis and immune cell development
11. Genetically Modified Natural Killer Immune Cells Attack, Kill Leukemia Cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... , March 24, 2015   Crossmatch ... solutions, today announced that its U.are.U ® ... retailer Goorin Bros . to achieve PCI ... solution secures access to the POS terminal, protecting ... risk of data breaches. With ...
(Date:3/23/2015)... March 23, 2015  In the 2014 fiscal year, ... conviction losses. This figure accounts for a fraction of ... The Nilson Report, exceeds $11 billion globally. The polygraph ... a crime has occurred. Investor Mark Saint Juste ... Joe Paolella partnered to administer the test ...
(Date:3/20/2015)... Mar. 19, 2015 Research and Markets ( ... Geometry - Global Strategic Business Report" report to their ... Hand Geometry in US$ Thousands. The report provides separate comprehensive ... Japan , Europe , ... and Rest of World. Annual estimates and forecasts ...
Breaking Biology News(10 mins):Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4
... life--is exploding as scientists worldwide discover the roles of ... organisms. The rapidly growing body of knowledge has created ... and system for describing, cataloging and comparing their findings. ... the RNA Ontology Consortium, has now been formed to ...
... The Institute of Bioengineering and Nanotechnology (IBN) has developed ... morphology of nanoparticles, which can be used in pharmaceutical ... was recently featured in the leading Chemistry journal, Angewandte ... on the invention. , Research Scientist Dr. Yu Han ...
... today released an automated literature search tool for ... is available as a free plug-in to Cytoscape ... to form a visual map of complex biological ... the biological causes of disease. , The Agilent ...
Cached Biology News:RNA project to create language for scientists worldwide 2RNA project to create language for scientists worldwide 3Breakthrough method in nanoparticle synthesis paves the way for new pharmaceutical and biomedical applications 2Agilent Technologies releases automated literature search tool for biology researchers 2Agilent Technologies releases automated literature search tool for biology researchers 3
(Date:4/16/2015)... April 16, 2015 Cytokinetics, Incorporated (Nasdaq: ... first quarter results on Thursday, April 30, 2015 at ... management will host a conference call at 4:30 PM ... the company’s outlook for the future. , The conference ... from the homepage and in the Investor Relations section ...
(Date:4/16/2015)... 16, 2015  Schulman Associates IRB, Inc., the industry-leading ... a long-term lease on Laboratory Drive in the heart ... . The location will house review board and service ... quality reviews and customer service to clients. ... Schulman in the deal, while Capital Associates Management, LLC ...
(Date:4/16/2015)... OncoTAb, Inc., a ... spin-out company, announced today the appointment of physician ... Chief Operating Officer (COO). Cooper brings to OncoTAb ... clinical diagnostic and biotechnology platforms in the fields ... extensive career transcends the field of medical and ...
(Date:4/16/2015)... - Portage Biotech Inc. ("Portage" or "the Company" )) ... to announce that the Company will be presenting  at ... be held in London, UK . ... James Mellon , a director of Portage, will ... programs at its subsidiaries, Portage Pharmaceuticals Ltd. ("PPL"), and ...
Breaking Biology Technology:Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3Schulman IRB to Open Office in Research Triangle Park, N.C. 2OncoTAb Names Dr. David L. Cooper as COO 2Portage to Present at Master Investor 2015 in London, UK 2Portage to Present at Master Investor 2015 in London, UK 3Portage to Present at Master Investor 2015 in London, UK 4
... research at the University of Pennsylvania demonstrates that ... nanoscale semiconductors. This represents a promising advance in ... that use light rather than electricity. The ... postdoctoral fellow Lambert van Vugt and graduate student ...
... Solid grounding in science is widely considered to be ... biochemists and pharmacists to physician assistants and physical therapists, ... in the fields of healthcare and science. Yet, for ... Harris Interactive for University of the Sciences ...
... 15, 2011 PharmAthene, Inc. (NYSE Amex: ... biological and chemical threats, announced today that it has ... proceeds for the Company of approximately $6.5 million. ... sold an aggregate of 1,857,143 units to certain institutional ...
Cached Biology Technology:Penn researchers break light-matter coupling strength limit in nanoscale semiconductors 2Penn researchers break light-matter coupling strength limit in nanoscale semiconductors 3Careers in Healthcare and Science? "Not Interested" Say Half of U.S. Teens 2Careers in Healthcare and Science? "Not Interested" Say Half of U.S. Teens 3Careers in Healthcare and Science? "Not Interested" Say Half of U.S. Teens 4PharmAthene Completes $6.5 Million Registered Direct Offering 2PharmAthene Completes $6.5 Million Registered Direct Offering 3
SYBR Green Nucleic Acid Dye...
... from an inert polymer with a unique split ... split septum caps for use with 384-well tall-chimney ... when used in conjunction with screw or clip-down ... pipetting equipment 384 septum caps may be ...
... system . The sensitive conductivity detector CE ... houses the measuring cell in a thermostatted environment. ... Data processing is provided by the CE ... the high pressure CE 4100 dual piston pump. ...
Sufficient reagents for 50 applications.Mitochondria Isolation Kit Reagent A, 50 ml Mitochondria Isolation Kit Reagent B, 500 l Mitochondria Isolation Kit Reagent C, 70 ml...
Biology Products: