Navigation Links
Immune cells cluster and communicate 'like bees,' researcher says
Date:3/13/2013

The immune system's T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new study by scientists at UC San Francisco.

"In the morning, each bee goes looking individually for a sugar source, then comes back to the hive and does a dance in front of the other bees describing the location of what it's found, which helps the hive decide collectively where the best source is," said senior scientist Matthew Krummel, PhD, a UCSF professor of pathology.

They don't bust the same moves as bees, but T cells gather together and communicate essential information to each other in a similar way, Krummel said, thereby helping to coordinate immune responses directed against invading pathogens. This discovery might lead to useful therapeutic interventions to fight disease, according to Krummel.

Results of the study were published online March 10 in Nature Immunology.

Krummel's lab team found that after individual T cells survey lymph nodes and sample foreign matter, such as vaccines, bacteria or viruses, they come together as a group during what he and his team call the "critical differentiation period." This occurs several hours to one day after exposure.

"They cluster together for the purpose of sharing information, transmitting what they've discovered about the new pathogen or vaccine, which in turn helps the immune system mount a coordinated response to the foreign matter," Krummel said.

The discovery is important, Krummel said, because it sheds light on an aspect of medicine that has long been obscure: how vaccines work. "We know that they are effective for years after a vaccination, but we don't know why. It seems that T-cell aggregation is a profound part of the reason."

Krummel's team found that the critical differentiation period is essential to the formation of what is known as a "memory pool," the mechan
'/>"/>

Contact: Jeffrey Norris
jeff.norris@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. U of Alberta researcher steps closer to understand autoimmune diseases
2. UCI-led study uncovers how Salmonella avoids the bodys immune response
3. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
4. Immune system implicated in prematurity complication
5. Key to immune system disease could lie inside the cheek
6. New immune defense enzyme discovered
7. New genetic mechanism of immune deficiency discovered
8. Carnegie Mellon fluorescent biosensor reveals mechanism critical to immune system amplification
9. Immune-response genes affecting breast tumor eradication
10. New screening technique yields elusive compounds to block immune-regulating enzyme
11. Breast-fed babies gut microbes contribute to healthy immune systems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Immune cells cluster and communicate 'like bees,' researcher says
(Date:8/28/2014)... available in German . ... built with the help of sophisticated assembly lines. Mobile assembly ... important part of these assembly lines. In the case of ... work stages arranged in a precise spatial and chronological sequence, ... line. , The creation of such an assembly line at ...
(Date:8/28/2014)... the first person to alert the world to Global ... be captured and stored underground. He says that Carbon ... the best way to avoid global warming getting out ... (Columbia University, New York) made the call during his ... where 150 scientists are meeting to discuss Carbon Capture ...
(Date:8/28/2014)... action is needed to ensure safeguards are in place ... PLOS ONE , researchers from Monash University, Stellenbosch ... combining results from different studies - to look at ... to determine whether they actually protect biodiversity. , ... an area from human exploitation made common sense, however, ...
Breaking Biology News(10 mins):Nanoscale assembly line 2Nanoscale assembly line 3Global warming pioneer calls for CO2 to be taken from atmosphere and stored underground 2Protected areas proven to protect biodiversity 2
... Expeditions in Computing program has awarded $10 million to ... at the California Institute of Technology and the University ... design of complex molecular and chemical systems based on ... of their study, molecular programs, are collections of molecules ...
... understand the decline and slow recovery of Atlantic salmon, ... fish native to New England rivers. Biologists agree that ... and Canada, but specific causes are difficult to determine ... may provide some answers. Thirty of 150 ...
... cause blood to clot and scabs to form when you ... cerebral malaria, an often lethal complication that occurs mostly in ... tropical and subtropical regions, malaria is one of the oldest ... the most studied pathogens of all time. Still, cerebral malaria, ...
Cached Biology News:Caltech researchers awarded $10M for molecular programming project 2Signals from the Atlantic salmon highway 2Signals from the Atlantic salmon highway 3Signals from the Atlantic salmon highway 4Johns Hopkins scientists discover what drives the development of a fatal form of malaria 2
(Date:8/28/2014)... 2014 Best Sanitizers, Inc., a leader ... processing industry, is asking industry professionals to prepare for ... the E2 soap they’re currently using to the Best ... Hand hygiene is critical to fighting cross-contamination and ... Six key criteria are identified to evaluate the effectiveness ...
(Date:8/28/2014)... Ind. A new research platform uses ... of tiny structures undergoing stress and heating, ... improve designs for microelectronics and batteries., This ... information about how heating and the surface ... properties. Researchers have discussed the merits of ...
(Date:8/28/2014)... The ability for organizations to attract ... allow individuals to perform at the highest of levels, ... looking to compete in this post–recession era. The ... as the sector increasingly focuses on the importance of ... have real results on the organization's development and the ...
(Date:8/28/2014)... August 28, 2014 Sterlitech is proud ... membranes to its stable of products . ... weight cut-offs and include membrane filters with surface charges. ... in customer demand for our membrane process testing equipment, ... of flat sheet membranes,” explains Sterlitech President Mark Spatz. ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2
... will be held Feb. 11-13 at the Waldorf-Astoria Hotel in New York ... ... YORK, Jan. 24 Gerson Lehrman Group (GLG) and the,Biotechnology Industry Organization ... information and,insights at the tenth annual BIO CEO & Investor Conference., ...
... Structure Synthesized,in the Lab, Team Completes Second Step ... Md., Jan. 24 A team of 17,researchers at ... largest,man-made DNA structure by synthesizing and assembling the 582,970 ... work, published,online today in the journal Science by Dan ...
... biostability company,that offers innovative technologies for stabilizing biological ... RNA at room,temperature, eliminating the need for cold ... skyrocketed over the past years due to its ... studies. However, RNA samples are,difficult to work with ...
Cached Biology Technology:Gerson Lehrman Group Announces Partnership With BIO to Provide Scientific Expertise for the BIO CEO & Investor Conference 2Gerson Lehrman Group Announces Partnership With BIO to Provide Scientific Expertise for the BIO CEO & Investor Conference 3Venter Institute Scientists Create First Synthetic Bacterial Genome 2Venter Institute Scientists Create First Synthetic Bacterial Genome 3Venter Institute Scientists Create First Synthetic Bacterial Genome 4Venter Institute Scientists Create First Synthetic Bacterial Genome 5Venter Institute Scientists Create First Synthetic Bacterial Genome 6Biomatrica's RNAstable(TM) Stabilizes RNA at Room Temperature 2Biomatrica's RNAstable(TM) Stabilizes RNA at Room Temperature 3
Rabbit Polyclonal antibody to Perilipin Applications: This antibody is useful for Western blot anlaysis where a band at ~60 kDa is seen....
Conveniently document gels, films and membranes with a high quality thermal printer. , Compact, footprint printer , Supplies 256 gray scale for high resolution, archive-quality thermal film prints...
... ICE-LAP3 Mch3 Lyophilized ... of enzyme regulation and kinetics, cleavage of target substrates, ... units/mg protein. One unit is defined as ... of Ac-DEVD-pNA Cat. No. 235400 per hour at 37 ...
HLA-DRbeta (DA2)...
Biology Products: