Navigation Links
Imaging technology could unlock mysteries of a childhood disease
Date:12/30/2013

ity for days using standard microscopy techniques. The MTRIPS can be used to complement other probe technology, such as GFP and gold nanoparticles.

Work done by graduate student Eric Alonas to concentrate the virus was essential to the project, Santangelo said. The concentration had to be done without adversely affecting the infectivity of the virus, which would have impacted its ability to enter host cells.

"It took quite a bit of work to get the right techniques to concentrate the RSV," he said. "Now we can make lots of infectious virus that's labelled and can be stored so we can use it when we want to."

To study the infection's progress in individual cells, the researchers faced another challenge: living cells move around, and following them complicates the research. To address that movement, the laboratory of Thomas Barker also in the Coulter Department used micro-patterned fibronectin on glass to create 50-micron "islands" that contained the cells during the study.

Among the mysteries that the researchers would like to tackle is why certain lung cells are severely infected while others appear to escape ill effects.

"If you look at a field of cells, you see huge differences from cell to cell, and that is something that's not understood at all," Santangelo said. "If we can figure out why some cells are exploding with virus while others are not, perhaps we can figure out a way to help the bad ones look more like the good ones."

In addition to those already mentioned, the research team included James Crowe, professor of pediatrics at Vanderbilt University; Elizabeth Wright, assistant professor in the School of Medicine at Emory University; Daryll Vanover, Jeenah Jung, Chiara Zurla, Jonathan Kirschman, Vincent Fiore, and Alison Douglas from the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University; Aaron Lifland and Manasa Gudheti from Vutara Inc. in Salt Lake City, and H
'/>"/>

Contact: John Toon
jtoon@gatech.edu
404-894-6986
Georgia Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. High-resolution 3-D imaging draws new picture of Golgis whereabouts during cell division
2. High-tech X-ray imaging technique to offer detailed look at engineered tissue
3. Radiographic imaging exposes relationship between obesity and cancer
4. Visualizing the past: Nondestructive imaging of ancient fossils
5. Kessler Foundation neuroimaging study sheds light on mechanisms of cognitive fatigue in MS
6. Cancer imaging centers get £35 million boost
7. Organic electronics: Imaging defects in solar cells
8. Molecular Imaging Agents: Targets, Technology, Markets, and Commercial Opportunities
9. Texas A&M research contributes to improved ultrasound imaging
10. Genome-wide imaging study identifies new gene associated with Alzheimers plaques
11. In the blink of an eye: X-ray imaging on the attosecond timescale
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Imaging technology could unlock mysteries of a childhood disease
(Date:8/26/2014)... feeding patients through a tube, in an intensive care ... practice of a certain amount of feeding per hour ... to a volume-based system, which calls for a certain ... a system was found to be effective in ICU ... the American Society for Parenteral and Enteral Nutrition,s (A.S.P.E.N.) ...
(Date:8/26/2014)... Unregulated trash burning around the globe is pumping far ... records. A new study led by the National Center ... of the world,s garbage is burned in such fires, ... health and climate change. , The new study provides ... pollutants such as particulates, carbon monoxide, and mercury that ...
(Date:8/26/2014)... an increased risk of autism among children of ... reflect the known increased risk associated with severe ... online publication in Molecular Psychiatry , investigators ... while a diagnosis of autism spectrum disorder was ... antidepressants during pregnancy than in those with no ...
Breaking Biology News(10 mins):Trash burning worldwide significantly worsens air pollution 2Trash burning worldwide significantly worsens air pollution 3Study calls into question link between prenatal antidepressant exposure and autism risk 2Study calls into question link between prenatal antidepressant exposure and autism risk 3
... canary in the coal mine, penguins are sounding ... world,s oceans, and the culprit isn,t only climate ... Oil pollution, depletion of fisheries and rampant ... penguin species, along with Earth,s warming climate, are ...
... current standard practice of giving infants and children 100 ... deprivation may actually inflict additional harm, researchers at UT ... by oxygen deprivation, known as hypoxic-ischemic brain injury, is ... long-term neurological damage among infants and children. This can ...
... Twelve investigators have received grants totaling $5 million ... of food allergy, a significant public health concern. ... is funded by the National Institute of Allergy ... Institutes of Health, and two advocacy groups, the ...
Cached Biology News:Penguins setting off sirens over health of world's oceans 2Penguins setting off sirens over health of world's oceans 3Penguins setting off sirens over health of world's oceans 4Resuscitation technique after brain injury may do more harm than good 2NIAID announces grants to stimulate food allergy research 2NIAID announces grants to stimulate food allergy research 3
(Date:8/26/2014)... San Diego, CA, and Bellingham, WA (PRWEB) August ... nanoscience and optical engineering, visions for next-generation wearable ... Light 2015 among numerous highlights at this year’s ... in the San Diego, California, Convention Center. More ... suppliers last week attended conferences, courses, an exhibition, ...
(Date:8/26/2014)... and REHOVOT, Israel , August 26, ... 3D printing specialist, Replica 3DM, supports NHS hospitals with surgery ...   - Performing surgery on 3D ... times; improves patient recovery and provides an effective aid for ... Ltd. (Nasdaq: SSYS ), a global leader ...
(Date:8/26/2014)... CA (PRWEB) August 26, 2014 The ... USD 8,020.1 million by 2020, according to a new ... personalized medicine and theranostics, and the subsequent introduction of ... factors driving market growth over the next six years. ... chronic diseases such as cancer, coupled with disease triggering ...
(Date:8/26/2014)... Aug. 26, 2014  Guardant Health, a healthcare ... oncology diagnostic products, has been recognized today by ... Technology Pioneer . As an innovator in non-invasive, ... companies across a wide variety of industries and ... Guardant360 ® , Guardant Health,s first commercially ...
Breaking Biology Technology:Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 2Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 3Brighter, Busier SPIE Optics + Photonics Draws International Crowd to San Diego 4Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 2Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 3Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 4Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 2World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 4World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 6Guardant Health Named a 2015 Technology Pioneer by World Economic Forum 2
... Sangamo BioSciences, Inc. (Nasdaq: SGMO ) today announced that the ... 28, 2010 , after the market closes. The press release will be followed ... open to the public via telephone and webcast. During the conference call, the ... , , ...
... EXTON, Pa. , July 21 ViroPharma Incorporated,s (Nasdaq: VPHM ... Wednesday, July 28, 2010 before the open of the U.S. financial markets. , ... The company will host a conference call and live ... the conference call, ViroPharma management will discuss the 2010 second quarter financial results and ...
... RESEARCH TRIANGLE PARK, N.C. , July 21 Chimerix, ... it has expanded its clinical management team with the appointment of ... and Herve Mommeja-Marin, MD, as Vice President of Clinical Research.   ... In these ...
Cached Biology Technology:Sangamo BioSciences Announces Second Quarter 2010 Conference Call and Webcast 2ViroPharma to Release 2010 Second Quarter Financial Results on July 28, 2010 2Chimerix Appoints Two New Vice Presidents to Clinical Management Team 2Chimerix Appoints Two New Vice Presidents to Clinical Management Team 3
... a commonly used technique for studying protein ... electrophoresed on SDS-PAGE and transferred to a ... they are probed with specific antibodies. Unlike ... of Southern and Northern blots, it has ...
... Basic Package Superior Protein Detection and ... ProXPRESS 2D Proteomic Imaging System is a ... proteomic and general life science research applications. ... use of all dyes in the UV ...
... our Regulatory Edition of Molecular Imaging (MI) ... for life science research and drug discovery ... with U.S. Food and Drug Administrations Code ... Electronic Records; Electronic Signatures [21 CFR Part ...
... Neutralizing synthetic peptide for OPA1-01009, OPEP-01009 is a 16 amino ... human DNA fragmentation factor (DFF). The sequence of this ... P - K - S - V - K - ... S - P - R - K(18). This ...
Biology Products: