Navigation Links
Identifying a mystery channel crucial for hearing
Date:10/24/2013

Our ability to hear relies on hair cells, sensory receptors that mechanically amplify low-level sound that enters the inner ear through a transduction channel. Although the transduction channel was characterized more than 30 years ago, researchers have been unable to identify its molecular components. A new study in The Journal of General Physiology could help lead to a definitive identification of this mystery channel.

Recent studies have suggested that members of the TMC family of membrane proteins are strong candidates as the components of the hair cell's transduction channel. Now, a team led by scientists from the University of Wisconsin Medical School provides evidence that the TMCs instead couple the transduction channel to tip linksthe mechanical elements that provide directional sensitivity to hair cellsand are not the channel itself. This suggests that the transduction channel may be a membrane protein distinct from TMCs that only functions properly once other key molecules are expressed.

Whether or not TMCs turn out to be the transduction channel, the new results affirm that they play a central role in hair cell mechanotransduction. The work adds to evolving research aimed at understanding the cellular and molecular mechanisms that affect hearing.


'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert  

Page: 1

Related biology news :

1. Beyond the microscope: Identifying specific cancers using molecular analysis
2. A new type of data papers designed to publish online interactive keys identifying biodiversity
3. Researchers develop new method for identifying lung nodules
4. UC research takes a new approach to identifying food deserts
5. Kidney stone mystery solved
6. UCLA life scientists unlock mystery of how handedness arises
7. Mystery to the origin of long-lived, skin-deep immune cells uncovered
8. New discovery provides insight on long-standing pregnancy mystery
9. Animal reservoir mystery solved
10. Mystery of elephant infrasounds revealed
11. Geologys Mystery Interval, the Great Deepening, and the largest kill-off in Earth history
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Identifying a mystery channel crucial for hearing
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/17/2017)... Florida , April 17, 2017 NXT-ID, ... technology company, announces the filing of its 2016 Annual Report on ... and Exchange Commission. ... on Form 10-K is available in the Investor Relations section of ... as on the SEC,s website at http://www.sec.gov . ...
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that ... Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los ...
(Date:10/10/2017)... BARBARA, CALIFORNIA (PRWEB) , ... October 10, 2017 ... ... management, technological innovation and business process optimization firm for the life sciences and ... BoxWorks conference in San Francisco. , The presentation, “Automating GxP Validation ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving Tree Wellness ... targeting the needs of consumers who are incorporating medical marijuana into their wellness ... Arizona. , As operators of two successful Valley dispensaries, The Giving Tree’s two ...
(Date:10/6/2017)... ... October 06, 2017 , ... ... healthcare and technology sector at their fourth annual Conference where founders, investors, innovative ... speakers and the ELEVATE pitch competition showcasing early stage digital health and med ...
Breaking Biology Technology: