Navigation Links
Identifying a mystery channel crucial for hearing
Date:10/24/2013

Our ability to hear relies on hair cells, sensory receptors that mechanically amplify low-level sound that enters the inner ear through a transduction channel. Although the transduction channel was characterized more than 30 years ago, researchers have been unable to identify its molecular components. A new study in The Journal of General Physiology could help lead to a definitive identification of this mystery channel.

Recent studies have suggested that members of the TMC family of membrane proteins are strong candidates as the components of the hair cell's transduction channel. Now, a team led by scientists from the University of Wisconsin Medical School provides evidence that the TMCs instead couple the transduction channel to tip linksthe mechanical elements that provide directional sensitivity to hair cellsand are not the channel itself. This suggests that the transduction channel may be a membrane protein distinct from TMCs that only functions properly once other key molecules are expressed.

Whether or not TMCs turn out to be the transduction channel, the new results affirm that they play a central role in hair cell mechanotransduction. The work adds to evolving research aimed at understanding the cellular and molecular mechanisms that affect hearing.


'/>"/>

Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert  

Page: 1

Related biology news :

1. Beyond the microscope: Identifying specific cancers using molecular analysis
2. A new type of data papers designed to publish online interactive keys identifying biodiversity
3. Researchers develop new method for identifying lung nodules
4. UC research takes a new approach to identifying food deserts
5. Kidney stone mystery solved
6. UCLA life scientists unlock mystery of how handedness arises
7. Mystery to the origin of long-lived, skin-deep immune cells uncovered
8. New discovery provides insight on long-standing pregnancy mystery
9. Animal reservoir mystery solved
10. Mystery of elephant infrasounds revealed
11. Geologys Mystery Interval, the Great Deepening, and the largest kill-off in Earth history
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Identifying a mystery channel crucial for hearing
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/5/2017)... 2017  The Allen Institute for Cell Science today ... one-of-a-kind portal and dynamic digital window into the human ... first application of deep learning to create predictive models ... and a growing suite of powerful tools. The Allen ... future publicly available resources created and shared by the ...
(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
Breaking Biology News(10 mins):
(Date:9/14/2017)... ... 14, 2017 , ... AIM Global, the worldwide standards agency for AIDC and ... 2017 Case Study Competition for AIDC. The award is given to those in ... push the adoption of automated data collection systems further. The TRACTUS platform, by ...
(Date:9/12/2017)... , ... September 12, 2017 , ... ... and highly scalable cloud-based platform for ambulatory patient monitoring and clinical trial support, ... Advance Clinical Trials conference in Boston. , Launched in 2005, PhysIQ leverages ...
(Date:9/12/2017)... ... September 12, 2017 , ... Soybean researchers ... to submit a "pre-proposal” by October 15, prior to completing a full grant ... are aligned with our priorities, and to encourage researchers to further develop ones ...
(Date:9/12/2017)... ... September 11, 2017 , ... Global molecular ... today that Holotype HLA and other Omixon products will be featured among eight ... American Society for Histocompatibility and Immunogenetics (ASHI) in San Francisco, CA. Additionally, ...
Breaking Biology Technology: