Navigation Links
Identical twins not as identical as believed
Date:2/15/2008

Contrary to our previous beliefs, identical twins are not genetically identical. This surprising finding is presented by American, Swedish, and Dutch scientists in a study being published today in the prestigious journal American Journal of Human Genetics. The finding may be of great significance for research on hereditary diseases and for the development of new diagnostic methods.

How can it be that one identical twin might develop Parkinsons disease, for instance, but not the other" Until now, the reasons have been sought in environmental factors. The current study complicates the picture.

Even though the genome is virtually identical in identical twins, our results show that there in fact are tiny differences and that they are relatively common. This could have a major impact on our understanding of genetically determined disorders, says Jan Dumanksi, who co-directed the international study with his colleague Carl Bruder.

By uncovering these small genetic differences in identical twins where one of them is sick, we have a way of tying specific genetic changes to the genesis of common diseases, says Carl Bruder.

These researchers studied 19 pairs of identical twins and found that they indeed had the same DNA but nevertheless evinced differences in the number of copies of individual DNA segments. A segment might be missing, or more copies might exist in one twin. This could explain how one identical twin can be afflicted with a disorder while the other twin remains fully healthy, according to the scientists.


'/>"/>

Contact: Jan Dumanski
Jan.Dumanski@genpat.uu.se
205-996-4042
Uppsala University
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers detect hint of oxygen 50 to 100 million years earlier than first believed
2. New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... Fla. , April 11, 2017 ... and secure authentication solutions, today announced that it ... Intelligence Advanced Research Projects Activity (IARPA) to develop ... Thor program. "Innovation has been a ... IARPA,s Thor program will allow us to innovate ...
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
Breaking Biology News(10 mins):
(Date:4/19/2017)... ... ... The Vibrating Orifice Aerosol Generator (VOAG) was developed in ... known diameters for research applications such as for calibrating droplet measuring instruments, for ... , The VOAG requires forcing liquid out of an orifice about half ...
(Date:4/19/2017)... ... 18, 2017 , ... Alisa Wright, founder and CEO of Singota Solutions ... of Pharmacy in Lafayette, Indiana. , The Distinguished Alumni Award was established in ... and other scientific endeavors. , Wright began her career in the pharmaceutical industry ...
(Date:4/19/2017)... ... April 19, 2017 , ... Nobilis Therapeutics Announces Completion of Landmark ... Clinical Data in its Upcoming Post Traumatic Stress Disorder Trial , Nobilis Therapeutics, ... trial assessing efficacy of its NBTX-001, a xenon-based therapeutic in the treatment of Panic ...
(Date:4/19/2017)... New York, NY (PRWEB) , ... April 19, ... ... working to combat Clostridium difficile (C. diff) infections through education and advocacy. ... lost her life to a C. diff infection, the foundation has become the ...
Breaking Biology Technology: