Navigation Links
Idaho researchers win grant to explore DNA frontier
Date:8/25/2009

MOSCOW, Idaho Three University of Idaho researchers will embark on an unconventional approach to DNA research as one of 20 teams chosen nationwide by federal officials for the ideas to explore scientific frontiers.

Chemist Patrick Hrdlicka and molecular physiologist Madhu Papasani, who are both 32, were the youngest researchers chosen among several hundred applicants. They will be joined on the University of Idaho team by a senior scientist, growth biology Prof. Rod Hill.

The award is the first awarded to researchers in Idaho through the Exceptional, Unconventional Research Enabling Knowledge Acceleration or EUREKA program sponsored by the National Institutes of Health.

The $523,000 R-01 program grant over three years reflects the team's approach as one that is exceptionally innovative and based on a novel approach that could have an extremely high impact on biomedical research conducted by the National Institutes of Health.

The Idaho team will explore new approaches to gene therapies by using locked nucleic acids or LNAs as invaders to target specific sections of chromosomes. The team will use zebrafish embryos in the study.

Their study will focus on ways to improve the targeting of the invader LNAs through chemical engineering and to show how they can affect the genes.

"We are very excited about having the support to explore this approach," Papasani said. "We are proud to be recognized as one of the teams that proposed an idea considered both exceptional and unconventional."

The researchers hope their work could help medical researchers speed the development of new drugs or lead to gene therapies that would be new approaches to treatment of diseases.

"We want to develop a chemical probe technology that binds more strongly to specific genetic sequences and can target many more sequences that is currently possible," Hrdlicka said. "If successful, this technology has the potential to treat
'/>"/>

Contact: Bill Loftus
bloftus@uidaho.edu
208-885-7694
University of Idaho
Source:Eurekalert

3

GOOD

Page: 1 2

Related biology news :

1. Canyon County Idaho Sheriffs Office to Purchase Stinger S-200s
2. UCSF researchers identify 2 key pathways in adaptive response
3. Disrupting a destructive duo: U of T Mississauga researchers inhibit cancer proteins
4. Researchers boost production of biofuel that could replace gasoline
5. Researchers find genetic link between physical pain and social rejection
6. UTSA biology researchers demystify elusive war zone bacterium
7. UGA researchers propose model for disorders caused by improper transmission of chromosomes
8. Researchers develop new, more-sensitive assay for detecting DNA methylation in colon cancer
9. NIH-funded researchers sequence exomes of 12 people
10. USC researchers identify regulatory genetic sequences that may predict risk for prostate cancer
11. K-State lab gives researchers the tools to study porcine circovirus associated diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2009)... ocean,s temperature variability and circulation system could help improve ... is affected more by surface warming than previously thought, ... factors such as sea level rise and ice volume ... found to result in a more vigorous deep ocean ... of large quantities of warm water, with possible impacts ...
(Date:12/11/2009)... been limited by the seasons, particularly in ... short. Thanks to researchers and fruit breeders, ... offer growers the ability to produce fruit ... both producers and consumers. Fresh examples are ... which bear fruit on current-season canes, or ...
(Date:12/11/2009)... is available in German . ... more plant introductions than extinctions, plant communities of ... same species are occurring more frequently, whereas rare ... the biological communities that are becoming increasingly similar, ... processes have led to a loss of uniqueness ...
Breaking Biology News(10 mins):New discoveries could improve climate projections 2New management methods extend blackberry season 2Europe's flora is becoming impoverished 2Europe's flora is becoming impoverished 3Med32 com 3A Medical Supply Marketplace Just What the Doctor Ordered 50358 1Med32 com 3A Medical Supply Marketplace Just What the Doctor Ordered 50358 2James R Andrews Renowned Orthopaedic Surgeon Installed as AOSSM President 50355 1James R Andrews Renowned Orthopaedic Surgeon Installed as AOSSM President 50355 2James R Andrews Renowned Orthopaedic Surgeon Installed as AOSSM President 50355 3Chiltern Opens Office in Budapest Hungary 50352 1Chiltern Opens Office in Budapest Hungary 50352 2
... The 21st Norsk Perinataldager (Norwegian Perinatal Days) will be ... Stillbirth Conference from the 5th 7th November. This ... and the World Health Organisation (WHO). The Norwegian Institute ... many researchers from the NIPH will present research on ...
... client base and,revenues, JERICHO, N.Y., Sept. 29 ... that it has executed a non-binding,Letter of Intent ... a controlling interest in Biometric Solutions, Inc. The ... Biometric Solutions LLC is a premiere engineering ...
... STATION, TX - A new generation has come of ... 1970. For this and future generations, environmental awareness is ... urban children live in environments that offer little chance ... to depend on sources such as television and educators ...
Other Biology News:bioMETRX, Inc. Signs Deal To Acquire Controlling Interest in Biometric Solutions, LLC 2bioMETRX, Inc. Signs Deal To Acquire Controlling Interest in Biometric Solutions, LLC 3Children's gardening programs grow environmental stewards 2
(Date:12/14/2009)... -- The third edition of Infusion ... published by the Infusion Nurses Society (INS), includes ... Anthracyclines are a group of chemotherapy medications ... been used in the treatment of various types ... ,, According to the INS publication: "In September ...
(Date:12/14/2009)... of Brookfield Engineering’s Powder Flow Tester – helping Brookfield move ... footprint and more compact design. , ... ... US-based thermoforming company, has completed the delivery of Brookfield Engineering’s ... to a plastic enclosure with a smaller footprint and more ...
(Date:12/11/2009)... -- Researchers have discovered a new explanation for differences in ... copies of a certain gene, the more serious the handicap. ... is suspected that it is the amount of copies of ... published in the American Journal of Human Genetics , ... Guy Froyen connected to VIB, a life sciences research institute ...
(Date:12/11/2009)... CAMBRIDGE, Mass., Dec. 11 Gwathmey, ... company specializing in cancer, staph aureus, and cardiovascular ... Pre-clinical Services announced today that Rosalie Dunn, Ph.D., ... Dr. Dunn has over 28 years of experience ... Prior to joining Gwathmey, Dr. Dunn managed ...
Breaking Biology Technology:Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 2Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 3Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 4Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 5Thermofab Helps Brookfield Engineering Move To A Compact Custom Plastic Enclosure 2Amount of gene surplus determines severity of mental retardation in males 2Rosalie Dunn, Ph.D., Joins Gwathmey, Inc. as Chief Executive Officer 2
... NEW YORK, Jan. 4 QED International,Associates, Inc., ... underlying indexes for the HealthShares(TM) Exchange-Traded Funds,today announced ... Monday, January,7, 2008, Maxygen, Inc. (Nasdaq: MAXY ... ) in the HealthShares(TM) Autoimmune-Inflammation Index.,Alpharma, Inc. (NYSE: ...
... Project to study technology to reduce greenhouse gas ... Daniels Midland,Company (NYSE: ADM ), the Midwest ... Survey (ISGS) announce that they are,working together on ... capture and storage of carbon dioxide from ADM,s ...
... Genome Sciences,Inc. (Nasdaq: HGSI ) announced today that ... be webcast and may be accessed,at http://www.hgsi.com , ... of Human Genome Sciences, senior management team will present,an ... at 7:30 am Pacific,Time, or 10:30 am Eastern Time., ...
Other Biology Technology:QED International Associates Announces Changes to the HealthShares(TM) Autoimmune-Inflammation and Neuroscience Indexes 2ADM, MGSC and ISGS Announce Carbon Sequestration Project 2ADM, MGSC and ISGS Announce Carbon Sequestration Project 3
ANTI S. ENTERID LPS...
B.D. Hames and D.M. Glover (1996) • This issue covers T-Cell antigen receptor genes; T-Lymphocyte signal transduction; B-Cell activation antibody engineering and the complement system and other ...
Request Info...
RABBIT ANTI PORCINE CARBOXYPEPTIDASE B...
Biology Products: