Navigation Links
IU researchers target vascular disease linked to cancer-causing gene mutation
Date:3/23/2010

ged blood vessel, ruling out potential effects from NF1 gene mutations in the blood vessel muscle cells and the cells that line the inside of the blood vessels.

In addition, they compared blood samples from a small group of human patients with and without the NF1 mutation and found that the neurofibromatosis patients had significant levels of inflammatory cells and other compounds that pose a higher risk of cardiovascular disease.

The IU researchers, in collaboration with Dr. Friedman in Vancouver, have begun a pilot clinical trial to evaluate potential diagnostic tests, including blood pressure monitoring and ultrasound tests of carotid arteries, that might enable physicians to discover and treat neurofibromatosis patients who are developing cardiovascular problems.

"We think that if we can demonstrate this association with vascular effects and the ability to diagnose them we could proceed to an intervention clinical trial. Statins have anti-inflammatory effects and there are other agents that could potentially be used," Dr. Ingram said.


'/>"/>

Contact: Eric Schoch
eschoch@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. NYU School of Medicine presents biomedical researchers Dart/NYU Biotechnology Achievement Awards
2. Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain
3. Researchers find Clostridium difficile is more common than MRSA in southeast community hospitals
4. Einstein researchers discover 2 new ways to kill TB
5. USC researchers identify key mechanism that guides cells to form heart tissue
6. Frogs, foam and fuel: University of Cincinnati researchers convert solar energy to sugars
7. U-M researchers solve a molecular mystery in muscle
8. Researchers introducing sustainable agriculture practices to improve food security
9. Carnegie Mellon researchers seek to control blood loss
10. Researchers characterize stem cell function
11. Penn researchers identify immune cells that fight parasites may promote allergies and asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... aimed at improving the food intake, health and quality ... is among three projects at the University of Waterloo ... Canadian Institutes of Health Research (CIHR). , Professor ... at Waterloo, and a Schlegel research chair in nutrition ... investigate why many Canadians living in long-term care homes ...
(Date:8/21/2014)... has implications for life in other extreme environments, both ... LSU Associate Professor of Biological Sciences Brent Christner and ... NSF, this week published a paper confirming that the ... meters (2600 feet) beneath the surface of the West ... more than 400 subglacial lakes and numerous rivers and ...
(Date:8/21/2014)... the water window? It consists of radiations in the ... by the water in biological tissues. New theoretical findings ... within the water window. These could be the basis ... of the biological samples or to be used in ... physical mechanism needed to efficiently generate the harmonic radiationswhich ...
Breaking Biology News(10 mins):Grants will fund landmark aging research at Waterloo 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 3800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 4Water window imaging opportunity 2
... similarities between Grenoble and Hollywood or between the researchers ... (IBS) and world-known filmmakers. However, scientists from these institutes ... movie. The actors are not celebrities but a protein ... this protein in action by freezing it at several ...
... that hopes to use a patient's own immune cells to ... a specialty procedure performed in only a handful of institutions, ... , Julian A. Kim, M.D., chief of surgical oncology at ... the National Institutes of Health for a five-year study that ...
... 12 surgeons and 21 surgical residents, video game skill ... a simulated surgery skills course, according to a report ... of the JAMA/Archives journals. , James C. Rosser Jr., ... colleagues asked 33 surgeons (21 residents and 12 attending ...
Cached Biology News:Freeze! Scientists film proteins at work by freezing them at different states 2
(Date:8/22/2014)... a study published today (August 22nd), in the ... the Champalimaud Neuroscience Programme establish the effect of ... of advanced genetic and optical techniques., "Serotonin is ... a wide range of brain functions, from the ... of complex emotional behaviours, This neurotransmitter is also ...
(Date:8/22/2014)... 2014 Ophthalmic drug delivery technologies ... challenging endeavors as the anatomy, physiology and biochemistry ... the foreign substances. Ocular drug delivery technologies provide ... and minimal use of needles; also it enables ... provides specific targeting within the ocular globe. On ...
(Date:8/22/2014)... -- Research and Markets has announced the ... & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market ... The global molecular biology enzymes market ... expected to grow at a CAGR of 13.74% to ... & reagents find applications in a large number of ...
(Date:8/22/2014)... 22, 2014 The identification of ... can be accelerated by exome sequencing. Built on ... the custom SeqCap EZ Developer system has been ... Watson will additionally present how he achieved coverage ... human and mouse exome kits. With over 236,000 ...
Breaking Biology Technology:From happiness to pain: Understanding serotonin's function 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Ocular Drug Delivery Technologies Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 4Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 2Global Molecular Biology Enzymes, Kits, & Reagents (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing) Market - Forecast to 2018 3Efficient Identification of Protein-Coding Variants in a Model Organism Through Exome Sequencing, New Webinar Hosted by Xtalks 2
... Update on Key Regulatory Milestones, SEATTLE, Sept. 11 ... MTA: CTIC) announced today that it will host an,investor ... investor day will,provide an update from executive management on ... meeting will be an,invitation-only event. A webcast and live ...
... the Top 100 Businesses in Boston-, Cambridge-Quincy, MA-NH and ranked No. ... ... Observant LLC is pleased to announce,that it has been named one of the ... 1,093 places it in the Top,22% of companies on the list. The list ...
... System Now Available to Nearly 30 Percent of ... ... unparalleled in modern,healthcare, Hoana Medical, Inc. and several Hawai,i unions are ... won,t be covered by insurance companies. Whereas typical,healthcare insurers like Blue ...
Cached Biology Technology:Observant LLC Makes the 2008 Inc. 5000 List 2Observant LLC Makes the 2008 Inc. 5000 List 3Hoana Medical and Hawai'i Union Health and Welfare Trust Funds Partner to Fix Healthcare 2Hoana Medical and Hawai'i Union Health and Welfare Trust Funds Partner to Fix Healthcare 3Hoana Medical and Hawai'i Union Health and Welfare Trust Funds Partner to Fix Healthcare 4Hoana Medical and Hawai'i Union Health and Welfare Trust Funds Partner to Fix Healthcare 5
... The Label IT siRNA Tracker ... Reagent provides a straight forward approach ... of your design, in an efficient ... tracking experiments. Subcellular localization and functional ...
... (A) and 36kDa (C) subunits Formulation: ... 500mM NaCl, 60mM 2-mercaptoethanol, 1mM MgCl2, ... and 0.1mg/ml serum albumin Properites: For ... Purification: DEAE chromatography, aminohexyl-agarose and gel ...
... IT siRNA Tracker Intracellular Localization Kit ... straight forward approach to directly label ... in an efficient yet non-destructive manner, ... localization and functional inhibition of target ...
... The Label IT siRNA Tracker Intracellular ... provides a straight forward approach to ... your design, in an efficient yet ... experiments. Subcellular localization and functional inhibition ...
Biology Products: