Navigation Links
IU discovery on animal memory opens doors to research on memory impairment diseases
Date:2/26/2013

ve typically been considered beyond the scope of nonhuman minds.

The study owes much to another quality these rodents share with humans: They love chocolate. "There's no amount of chocolate you can give to a rat which will stop it from eating more chocolate," Crystal said.

Using chocolate as bait in an eight-arm radial maze, the study was made up of a series of five experiments that together provide converging evidence. In the first two, in order to obtain the chocolate, the rats needed to remember the source by which they acquired it, whether they were placed near the trough containing the chocolate or had to run on their own to get there. Using different mazes helped rule out the possibility that overlearned cues from a particular maze led to the positive results.

A third experiment showed that the rats' source memory, the means by which it retrieved the chocolate, lasted for a week rather than the one day that other, more ordinary forms of memory last. This provided converging evidence, said Crystal, that the rats were relying on source memory insofar as source memories decay more slowly than other memory systems.

In the fourth experiment, the rats could obtain the chocolate when the researcher placed them at the trough. The rats remembered this rule, too. Finally, in the fifth experiment, researchers temporarily disabled the rats' hippocampus, the brain region thought to be crucial for accurate source memory. If the task requires source memory, inactivating that area would impair the ability to remember source information, which it did.

"What we're trying to do is to develop behavioral approaches with rodents that tap into those types of memory systems," Crystal said. "This study is the demonstration, the proof of the concept that source memory exists in animals. But the mechanism that supports it is open. We're now interested in working out the sub-areas of the hippocampus that are involved in episodic memory, t
'/>"/>

Contact: Liz Rosdeitcher
rosdeitc@indiana.edu
812-855-4507
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Cell discovery could hold key to causes of inherited diseases
2. New scorpion discovery near metropolitan Tucson, Arizona
3. The discovery of a new genus of crustacean and 5 new species
4. A*STAR scientists groundbreaking discovery of nucleus structure crucial to understanding diseases
5. Discovery of sexual mating in Candida albicans could provide insights into infections
6. New discovery in autism-related disorder reveals key mechanism in brain development and disease
7. Discovery of Africa moth species important for agriculture, controlling invasive plants
8. Discovery may pave way to genetically enhanced biofuel crops
9. LSUHSC research discovery provides therapeutic target for ALS
10. Discovery of pathway leading to depression reveals new drug targets
11. Discovery of 100 million-year-old regions of DNA shows short cut to crop science advances
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
IU discovery on animal memory opens doors to research on memory impairment diseases
(Date:7/11/2014)... Wildlife Conservation Society shows that no-take zones in ... such as lobster, conch, and fish recover from ... areas. , The reporttitled "Review of the Benefits ... literature from no-take areas around the world. The ... recognized expert in marine protected areas and fisheries ...
(Date:7/11/2014)... 11, 2014--Researchers at the Department of Energy,s Oak ... awards, presented by R&D Magazine in recognition of ... awards recognize the tremendous value of our National ... and development at the National Labs continues to ... pursue the scientific and technological innovations necessary to ...
(Date:7/11/2014)... were many fires burning in eastern New South Wales, ... 11. , At 03:35 UTC on July 11 (12:35 ... Aqua passed over eastern New South Wales (NSW), the ... visible image of the region and spotted smoke (light ... MODIS,s thermal bands, are outlined in red. , The ...
Breaking Biology News(10 mins):Belize's lobster, conch, and fish populations rebuild in no-take zones 2ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4
... OTO EXPO of the American Academy of Otolaryngology Head ... nose, and throat doctors in the world, will convene September ... 305 scientific research sessions, 594 posters, and several hundred instruction ... opportunity for journalists from around the world to cover breaking ...
... Carolina State University researcher has shown that water-gel-based solar ... cells to produce electricity. The findings prove the concept ... They also have the potential to be less expensive ... solar cells. The bendable devices are composed of ...
... determined that teenagers who have abortions are no more likely ... whose pregnancies do not end in abortion. The study ... California, San Francisco, is the first to use both depression ... of adolescents. The researchers found that young women in ...
Cached Biology News:2010 AAO-HNSF miniseminars: Sunday, Sept. 26, 2010 22010 AAO-HNSF miniseminars: Sunday, Sept. 26, 2010 3Mimicking nature, water-based 'artificial leaf' produces electricity 2National study: Abortion does not cause depression or low self-esteem in adolescents 2National study: Abortion does not cause depression or low self-esteem in adolescents 3
(Date:7/11/2014)... PALM BEACH, Fla. , July 11, 2014 /PRNewswire-iReach/ ... variety of high-quality peptides that are used solely in ... To honor two successful years in business, Maxim Peptide, ... LLC, has just launched a new and updated website ... the research blog section has been updated with fascinating ...
(Date:7/11/2014)... July 11, 2014 , Not for ... into or from any jurisdiction where to do so would ... Shire plc ("Shire" or the "Company") (LSE: SHP, ... afternoon.  Shire confirms it has held a meeting with representatives ... Shire without the prior agreement or approval of AbbVie. ...
(Date:7/11/2014)... July 11, 2014 Research and Markets ... Technology Market - Global Industry Analysis, Size, Share, Growth, ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... acids (either DNA or RNA) into cells. This technology ... cancer cells and protein metabolism by affecting the nuclear ...
(Date:7/11/2014)... July 11, 2014 BCC Research ( ... DIGITAL POLYMERASE CHAIN REACTION (PCR) TECHNOLOGY: GLOBAL MARKETS , ... technology reached nearly $140 billion in 2013. This is ... a five-year compound annual growth rate (CAGR) of 28.6%. ... of interesting and exciting possibilities within the broader PCR ...
Breaking Biology Technology:Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2Shire plc - Statement re: Media Speculation 2International Transfection Technology Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2019 2Global Market for Digital Polymerase Chain Reaction Technology to Reach $490 Billion by 2018; Equipment Sector Accounts for the Fastest Growing Segment With 33% CAGR 2Global Market for Digital Polymerase Chain Reaction Technology to Reach $490 Billion by 2018; Equipment Sector Accounts for the Fastest Growing Segment With 33% CAGR 3
... 11 Amicus Therapeutics,(Nasdaq: FOLD ), today announced ... at the 5th Annual Lazard Capital Markets Healthcare,Conference in ... p.m. EST., A webcast and audio archive of ... at http://www.amicustherapeutics.com . Participants,should allow approximately five to ...
... a privately-held,biopharmaceutical company focused on developing novel cancer ... viral vector, today announced,that executive management will participate ... to be held November 10 through November 12,2008 ... York City. Frank D. Stonebanks,President and Chief Executive ...
... Calif., Nov. 11 Cord Blood,America, Inc. (OTC ... preservation company ( http://www.cordblood-america.com ) focused on,bringing the ... nationwide and,internationally, said today that the stem cell ... Obama intends to use his executive,authority to reverse ...
Cached Biology Technology:Cord Blood America Salutes President-Elect Obama's Promise to Lift Restrictions on Stem Cell Research 2
Mouse Anti-Amyloid beta [1-16], clone 6E10, Monoclonal Antibody...
The pCDF Expression System 1 plus Competent Cells contains 10 µg of pET-45b(+) DNA. pET-45b carries an N-terminal His•Tag ® coding sequence that is cleavable with enterokinase as well...
Nucleobindin 1 [NUCB1]...
Request Info...
Biology Products: