Navigation Links
IU discovery on animal memory opens doors to research on memory impairment diseases
Date:2/26/2013

ve typically been considered beyond the scope of nonhuman minds.

The study owes much to another quality these rodents share with humans: They love chocolate. "There's no amount of chocolate you can give to a rat which will stop it from eating more chocolate," Crystal said.

Using chocolate as bait in an eight-arm radial maze, the study was made up of a series of five experiments that together provide converging evidence. In the first two, in order to obtain the chocolate, the rats needed to remember the source by which they acquired it, whether they were placed near the trough containing the chocolate or had to run on their own to get there. Using different mazes helped rule out the possibility that overlearned cues from a particular maze led to the positive results.

A third experiment showed that the rats' source memory, the means by which it retrieved the chocolate, lasted for a week rather than the one day that other, more ordinary forms of memory last. This provided converging evidence, said Crystal, that the rats were relying on source memory insofar as source memories decay more slowly than other memory systems.

In the fourth experiment, the rats could obtain the chocolate when the researcher placed them at the trough. The rats remembered this rule, too. Finally, in the fifth experiment, researchers temporarily disabled the rats' hippocampus, the brain region thought to be crucial for accurate source memory. If the task requires source memory, inactivating that area would impair the ability to remember source information, which it did.

"What we're trying to do is to develop behavioral approaches with rodents that tap into those types of memory systems," Crystal said. "This study is the demonstration, the proof of the concept that source memory exists in animals. But the mechanism that supports it is open. We're now interested in working out the sub-areas of the hippocampus that are involved in episodic memory, t
'/>"/>

Contact: Liz Rosdeitcher
rosdeitc@indiana.edu
812-855-4507
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Cell discovery could hold key to causes of inherited diseases
2. New scorpion discovery near metropolitan Tucson, Arizona
3. The discovery of a new genus of crustacean and 5 new species
4. A*STAR scientists groundbreaking discovery of nucleus structure crucial to understanding diseases
5. Discovery of sexual mating in Candida albicans could provide insights into infections
6. New discovery in autism-related disorder reveals key mechanism in brain development and disease
7. Discovery of Africa moth species important for agriculture, controlling invasive plants
8. Discovery may pave way to genetically enhanced biofuel crops
9. LSUHSC research discovery provides therapeutic target for ALS
10. Discovery of pathway leading to depression reveals new drug targets
11. Discovery of 100 million-year-old regions of DNA shows short cut to crop science advances
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
IU discovery on animal memory opens doors to research on memory impairment diseases
(Date:8/28/2014)... the developmental on-off switch for Streptomyces , a ... of the world,s naturally derived antibiotic medicines. , ... is possible to manipulate this switch to make nature,s ... August 28 in Cell , found that a ... a larger protein called BldD ultimately controls whether a ...
(Date:8/28/2014)... 2014A new method for measuring and imaging how quickly ... researchers better understand how drug abuse affects the brain, ... engineering, and lead to better treatment options for recovering ... of researchers from Stony Brook University in New York, ... published today in The Optical Society,s (OSA) open-access journal ...
(Date:8/28/2014)... Broeker, the first person to alert the world to ... to be captured and stored underground. He says that ... is the best way to avoid global warming getting ... Broeker (Columbia University, New York) made the call during ... Iceland, where 150 scientists are meeting to discuss Carbon ...
Breaking Biology News(10 mins):Small molecule acts as on-off switch for nature's antibiotic factory 2Small molecule acts as on-off switch for nature's antibiotic factory 3This is your brain's blood vessels on drugs 2This is your brain's blood vessels on drugs 3Global warming pioneer calls for CO2 to be taken from atmosphere and stored underground 2
... is pleased to announce the recipients of its 2010 ... at the Society,s 54th Annual Meeting on Monday, February ... in San Francisco, California. The awardees are: ... and ,Harvard Medical School will receive the Anatrace Membrane ...
... This release is available in German . ... and maintenance of the Earth,s multi-trillion dollar ecosystems - from ... have a key role in countering climate change and climate-proofing ... a new climate issues update by The Economics of Ecosystems ...
... widely recognized for his expertise in the identification and ... recipient of the Charles River Laboratories, Excellence in Refinement ... at the 7th World Congress on Alternatives and Animal ... by Charles River Laboratories, in cooperation with the Johns ...
Cached Biology News:Biophysical Society names 2010 award recipients 2Time to tap climate change-combating potential of the world's ecosystems 2Time to tap climate change-combating potential of the world's ecosystems 3Time to tap climate change-combating potential of the world's ecosystems 4Time to tap climate change-combating potential of the world's ecosystems 5
(Date:8/29/2014)... Boston, MA (PRWEB) August 29, 2014 ... ones in the biotech start-up dense realm of Boston-Cambridge, ... alliances and able investors. James Sherley, the Director of ... made increasing the local and national visibility of his ... in September 2013. , In addition to a social ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Best Sanitizers, ... for the food processing industry, is asking industry professionals ... side comparison of the E2 soap they’re currently using ... Foam Soap . Hand hygiene is critical to ... food processing environment. Six key criteria are identified to ...
(Date:8/28/2014)... WEST LAFAYETTE, Ind. A new research ... "nanomechanical" properties of tiny structures undergoing stress ... insights to improve designs for microelectronics and ... spectroscopy, reveals information about how heating and ... their mechanical properties. Researchers have discussed the ...
(Date:8/28/2014)... Willow Grove, PA (PRWEB) August 28, 2014 ... talent, and create a culture that will allow individuals ... that are becoming increasingly important for employers looking to ... life science industries are embracing this trend, as the ... the fabric of a company, which will have real ...
Breaking Biology Technology:The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... from Stevens Institute of Technology, consisting of undergraduate ... Jing, Xi Chen, and Zhenbo Fu and led ... Shi from the Department of Mechanical Engineering, placed ... Institute of Standards and Technology (NIST) Mobile Microrobotics ...
... and MARCY L,ETOILE, France , May 21 ... have entered into a partnership to commercialize a mass ... will work with Shimadzu and their subsidiary, Kratos Analytical, ... optimized integration into the microbiology laboratory workflow. This new ...
... /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE YMI, TSX:YM), today announced ... results from several global nimotuzumab trials in adults with Glioblastoma ... the American Society of Clinical Oncology annual meeting held from ... The trials are being conducted by Oncoscience AG (Wedel, ...
Cached Biology Technology:Stevens team places third in 2010 IEEE/NIST Mobile Microrobotics Challenge 2Shimadzu and bioMerieux Enter into Partnership for Mass Spectrometry Applications in Microbiology 2Shimadzu and bioMerieux Enter into Partnership for Mass Spectrometry Applications in Microbiology 3Shimadzu and bioMerieux Enter into Partnership for Mass Spectrometry Applications in Microbiology 4YM BioSciences announces presentations on global nimotuzumab trials at ASCO annual meeting 2YM BioSciences announces presentations on global nimotuzumab trials at ASCO annual meeting 3YM BioSciences announces presentations on global nimotuzumab trials at ASCO annual meeting 4YM BioSciences announces presentations on global nimotuzumab trials at ASCO annual meeting 5
... Features hardwall acrylic panels mounted ... to form a free-standing modular ... Class 10/ISO 3. Optional ceiling ... ionizers are configured to customer ...
... highly sensitive reagent for the detection of ... form of recombinant E. coli phosphate-binding protein ... sensitive to changes in its environment.How it ... is rapid and tight (Kd ~ 0.1 ...
Sigmas E-TOXATE (Limulus Amebocyte Lysate) test kits are intended for the detection and semiquantitation,of endotoxins for research purposes....
... These versatile enclosures are ... nitrogen or other process ... low-humidity environment. HEPA filtration, ... ionization modules also available, ...
Biology Products: