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IRSF announces 2013 awards and implements new Translational Program
Date:2/24/2014

Cincinnati, (OH) The International Rett Syndrome Foundation (IRSF) announces today ten (10) new research grants at leading global research institutions; a new Translational Research Program; and additional funding for current human clinical trials.

The funding awarded in 2013 covers the spectrum of Rett syndrome research, from basic discovery starting at the genetic level all the way to treating the girls diagnosed with Rett syndrome. Awards are not restricted by geographic boundaries, and several of the new IRSF grants are invested in researchers from Canada and Australia. IRSF remains steadfast in recruiting talented young scientists to the research bench for Rett syndrome, and welcomes three new IRSF fellows into the IRSF training fellowship program.

In an effort to move potential therapeutics past the translational research funding gap and into clinics, IRSF announces the Scout Program, a Drug Discovery Screen in a mouse model of Rett syndrome that will aggressively accelerate the testing of compounds, whether new or repurposed, through standardized preclinical studies. The Scout Program was created to replicate and confirm encouraging results stemming from studies performed in academic labs as well as testing of compounds no labs are pursuing. The Contract Research Organization (CRO) PsychoGenics, Inc. in Tarrytown, NY is the testing bed for this program and will independently test selected drugs using the set standards in preclinical studies for Rett syndrome. Outcomes from this program will provide the complementary high quality data required to move promising compounds through federal review and along the drug development pipeline toward the clinic.

"IRSF is taking the next logical step forward in developing programs that move the basic science discovery findings forward to rigorist pre-clinical trials. This is in concert with recent announcements and publications coming out of the National Institutes of Health fo
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Contact: Steven Kaminsky
skaminsky@rettsyndrome.org
International Rett Syndrome Foundation
Source:Eurekalert

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