Navigation Links
IOF urges systematic osteoporosis management after vertebral fracture augmentation
Date:8/1/2011

A working group of the International Osteoporosis Foundation (IOF) has issued a literature review of prospective controlled studies comparing the efficacy and safety of two minimally invasive techniques for vertebral augmentation after spine fracture: vertebroplasty (VP) and balloon kyphoplasty (BKP). The review also lists important recommendations to facilitate the comparison of future studies and highlights research questions still unresolved.

Vertebral fractures, most often due to osteoporosis, are associated with acute or chronic back pain, disability and kyphosis (stooped back). One in five women with a vertebral fracture will sustain another within a year, which may lead to a 'cascade' of fractures. Vertebral fractures impact severely on quality of life and may have serious health consequences such as spinal deformity, immobility, decreased pulmonary function, early satiety and impaired gait. Clinical vertebral fractures are also associated with an 8-fold increase in mortality.

Conservative treatment of vertebral fractures is typically through rest, pain medication, bracing and muscle relaxants. VP and BKP are two minimally invasive techniques that consist of inserting a bone cement into the compressed vertebra and stabilising the fracture.

In the studies observed, the review found that:

  • Overall, VP and BKP are relatively safe procedures and serious complications are rare.
  • In the short term, VP and BKP provide quicker pain relief and mobility recovery than does conservative treatment alone.
  • VP and BKP are able to stabilise the fracture and in some cases restore lost vertebral body height.
  • The added benefit of injecting cement over a sham-controlled surgery is still contentious.
  • The clinical outcome after VP and BKP appears to be dependent on the time elapsed between the fracture and the intervention.
  • The incidence of new (including adjacent) vertebral fractures are similar after VP or BKP, but longer term data are required.
  • Further studies are needed with standardised and systematic reporting of health outcomes and complications.

Kristina kesson, chair of the IOF Fracture Working Group and Professor at the Department of Orthopedics, Skne University Hospital Malm in Sweden, stated, "Referring physicians should be aware that VP and BKP are available options for the management of vertebral compression fractures, with possible clinical benefits to their patients in terms of acute pain relief and improved quality of life. However, longer follow-up of patients are needed to ensure the efficacy and safety of these techniques, which should not be considered as a substitute for the medical management of osteoporosis, vitally needed in these patients at high risk of other fractures."


'/>"/>

Contact: L. Misteli
info@iofbonehealth.org
41-229-940-100
International Osteoporosis Foundation
Source:Eurekalert

Related biology news :

1. Strong El Niño could bring increased sea levels, storm surges to US East Coast
2. Innovation Task Force urges approval of America COMPETES Act
3. Storm Surges Congress 2010 -- scientists from 30 countries meet in Hamburg
4. UF researcher urges caution in reducing blood pressure in patients with diabetes, coronary disease
5. SNM urges Congress to support CARE bill
6. FCSO Selects Burgess as Exclusive Pricing Solution for New Medicare Contract
7. Top scientific meeting urges coordinated response to economic and environmental crises
8. Molecular methods are not sufficient in systematics and evolution
9. Space agencies join forces to systematically observe climate variables
10. Experts discuss applying systematic review to the field of nutrition
11. Registration opens for first Middle East and Africa osteoporosis meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... SAN FRANCISCO and BANGALORE, India ... part of EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... service provider, today announced a global partnership that ... convenient way to use mobile banking and payment services. ... Mobility is a key innovation area for financial services, but ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/13/2016)... physicians supporting Medicaid patients in Central Florida ... telehealth thanks to a new partnership with higi.   ... can routinely track key health measurements, such as blood ... they opt in, share them with IMPOWER clinicians through ... location at no cost. By leveraging this data, IMPOWER ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... CLEVELAND , June 27, 2016  Global ... average 4.6 percent through 2020 to $7.2 billion.  ... (food and beverages, cleaning products, biofuel production, animal ... and biotechnology, diagnostics, and biocatalysts). Food and beverages ... gains driven by increasing consumption of products containing ...
(Date:6/27/2016)... ... June 27, 2016 , ... Parallel 6 , the leading software as ... Clinical Reach Virtual Patient Encounter CONSULT module which enables both audio and video ... trial team. , Using the CONSULT module, patients and physicians can schedule a face ...
(Date:6/27/2016)... --  Ginkgo Bioworks , a leading organism design ... awarded as one of the World Economic Forum,s ... innovative companies. Ginkgo Bioworks is engineering biology to ... in the nutrition, health and consumer goods sectors. ... including Fortune 500 companies to design microbes for ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita Politecnica delle Marche in ... peritoneal or pleural mesothelioma. Their findings are the subject of a new article on ... biomarkers are signposts in the blood, lung fluid or tissue of mesothelioma patients that ...
Breaking Biology Technology: