Navigation Links
IOF calls for improved strategies to close the treatment gap and reduce future burden of fractures
Date:6/17/2011

It pays to prevent fractures. That's one of the main findings of a landmark report 'Osteoporosis Burden, Healthcare provision and Opportunities in the European Union' newly published in the journal Archives of Osteoporosis. The study, compiled by the International Osteoporosis Foundation (IOF) in collaboration with the European Federation of the Pharmaceutical Industries and Associations (EFPIA), calculates the future burden of fractures as a consequence of increasing treatment uptake in the five largest European countries as well as Sweden.

Fragility fractures, which affect as many as one in three women and one in five men over the age of 50, have immense social and health economic consequences. In the six countries studied, an estimated 2.46 million fragility fractures occurred in 2010 (280 fractures per hour). The result is often severe loss of quality of life, long-term disability, loss of independence, or even early death in the six countries, 80 deaths per day are attributed to fractures. Fractures are expensive for healthcare systems as they involve immediate medical care, rehabilitation and nursing care for the elderly who may consequently suffer from long-term disability.

Improving treatment uptake to prevent future fractures: Largely due to the ageing of the population, the annual number of fractures in France, Germany, Italy, Spain, the UK and Sweden is expected to increase by 28.9% in 2025 - from a current 2.46 million to approximately 3.17 million. The total monetary burden in these six countries alone is expected to increase from 30.7 Billion in 2010 to 38.5 Billion in 2025.

Low treatment uptake is identified as a major problem. People at high risk of fracture are simply not being identified and referred for preventative treatment, while approximately 50% of those who are identified for pharmacological intervention don't follow their prescribed treatment and/or discontinue treatment within one year.

The report found that increasing treatment uptake to provide all individuals with a 10-year probability of fracture exceeding that of an age and sex-matched individual with a previous fracture with a 3-year treatment would require a 2.4-fold increase in provision of treatment. As a result, a significant number of future fractures could be avoided cost-effectively in the six European countries studied:

  • Increasing treatment uptake in the six countries would result in 95,000 fewer fractures and 33,357 Quality of Life Years (QALYs) gained annually in 2025;

  • The accumulated number of potentially avoided fractures from increasing uptake up to 2025 was estimated at 699,000;

  • 13% of the projected increase in fractures and 20% of the projected increase in lost QALYs could cost-effectively be avoided.

"There is a large gap between the number of people that are treated compared to the number that are eligible for treatment based on fracture risk, " stated IOF President John Kanis, Emeritus Professor in Human Metabolism and the Director of the WHO Collaborating Centre for Metabolic Bone Diseases at the University of Sheffield. "By decreasing that gap, and simultaneously improving adherence to treatment, we could significantly reduce the future human and health economic burden of fractures in Europe," he said.


'/>"/>

Contact: L. Misteli
info@iofbonehealth.org
41-229-940-100
International Osteoporosis Foundation
Source:Eurekalert

Related biology news :

1. IOF calls on European citizens to stand tall and speak out for their bones
2. NOAA report calls flame retardants concern to US coastal ecosystems
3. Rutgers study finds many consumers ignore food product recalls
4. Research supports calls to study health benefits of nitrate, nitrite
5. Recalls, food worries spark booming business in food safety
6. ISWA calls attention to important contribution of waste sector to reduce substantial CO2 emissions
7. Wildlife Conservation Society finds wild cat mimicking monkey calls
8. Diabetic adults conditions improved after phone calls with fellow patients
9. MU scientist develops salmonella test that makes food safer, reduce recalls
10. New study calls for greater awareness of food supply for children with diabetes
11. Bioethics Commission calls for enhanced federal oversight in new field of synthetic biology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... attendance control systems is proud to announce the introduction of fingerprint attendance control software, ... employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - http://photos.prnewswire.com/prnh/20160609/377487 ...
(Date:6/3/2016)... , June 3, 2016 ... von Nepal hat ... Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung ... in der Produktion und Implementierung von Identitätsmanagementlösungen. ... Ausschreibung im Januar teilgenommen, aber Decatur wurde ...
(Date:6/2/2016)... Perimeter Surveillance & Detection Systems, Biometrics & ... & Other Service  The latest report from ... of the global Border Security market . Visiongain ... billion in 2016. Now: In November 2015 ... and hardware technologies for advanced video surveillance. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network ... Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is ... projects are designed, built and brought to market. , The Design Lab is ...
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
(Date:6/23/2016)... 23, 2016 On Wednesday, June 22, ... down 0.22%; the Dow Jones Industrial Average edged 0.27% lower ... 2,085.45, down 0.17%. Stock-Callers.com has initiated coverage on the following ... Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ... BIND ). Learn more about these stocks by accessing ...
(Date:6/23/2016)... ... 23, 2016 , ... Velocity Products, a division of Morris ... optimized exclusively for Okuma CNC machining centers at The International Manufacturing Technology Show, ... several companies with expertise in toolholding, cutting tools, machining dynamics and distribution, Velocity ...
Breaking Biology Technology: