Navigation Links
Hypertension treatment effective in reversing vascular damage
Date:6/17/2008

WINSTON-SALEM, N.C. A hypertension medication called olmesartan medoxomil is effective in reversing the narrowing of the arteries that occurs in patients with high blood pressure, according to a new study.

Carlos M. Ferrario, M.D., one of the study's lead investigators and director of the Hypertension and Vascular Research Center at Wake Forest University Baptist Medical Center, said, "We believe the data add to the growing evidence for the role of angiotensin receptor blockers in preventing or reversing vascular damage at many stages during this disease process."

The one-year study, titled Vascular Improvement with Olmesartan medoxomil Study (VIOS), was published in the current Journal of the American Society of Hypertension. The study evaluated the effects of an angiotensin receptor blocker (olmesartan medoxomil) vs. a beta-blocker (atenolol) on vascular function and structure in patients with stage 1 hypertension.

Olmesartan medoxomil is marketed in the United States as Benicar and in Europe as Olmetec by Daiichi Sankyo, Inc., which funded the study.

After one year of treatment, olmesartan medoxomil improved the artery abnormalities in high blood pressure patients and returned arterial architecture to normal levels. This was not seen with the atenolol.

Olmesartan medoxomil is a member of a class of antihypertensive medications that help lower blood pressure by blocking the angiotensin II receptor on the blood vessels that causes constriction and increase blood pressure. This medication also blocks the release of a hormone that causes salt retention and increased blood volume.

Hypertension affects one in three Americans and, if left uncontrolled for a long time, can cause organ damage, as well as heart disease, stroke and other problems.

Olmesartan is currently being reviewed in several trials, including the Randomized Olmesartan and Diabetes Microalbuminuria Prevention study (ROADMAP), whi
'/>"/>

Contact: Ann Hopkins
ahopkins@wfubmc.edu
336-716-1280
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rare genetic mutations protect against hypertension
2. Researchers discovery may lead to hypertension treatment
3. Ultra-low-dose aspirin might decrease bleeding severity in portal hypertension
4. Understanding hypertension in African Americans proves elusive
5. Rong Li Lab identifies new role of inflammatory protein in PKD and a possible treatment
6. Source of drug-tolerant tuberculosis possibly behind TB relapses, intensity of treatment
7. Novel therapeutic strategy for colon cancer treatment
8. New ballast treatment could protect Great Lakes fish
9. Quest for better treatment for effects of menopause
10. Sugar linkage could lead to better treatment for autoimmune diseases
11. Glypican-3 gene function in regulating body size helps inform novel cancer treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research ... http://photos.prnewswire.com/prnh/20130307/600769 ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) ... Market in the APAC Region 2015-2019"  report to ... emerging in this market is advances in technology. ... to upgrade biometric solutions to the latest standard ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here ... account but can,t remember your password, site key or the ... was your first grade teacher? Today, ... the app that will finally put an end to ... 1U TM . 1U leverages a user,s smartphone ...
(Date:12/10/2014)... , Dec. 08, 2014 Research and ... the addition of the "Biometrics Market in ... http://photos.prnewswire.com/prnh/20130307/600769 ... projects such as rural banking and upgradation of ... trends witnessed in the market. Besides the aforementioned ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... paleoclimatology and ecology have paid homage to a king of ... him. The November issue of EARTH Magazine introduces ... thought to live alongside mammals during the Eocene. Find ... after and what gave it the evolutionary edge to successfully ...
... high-resolution X-ray imaging (termed microCT), 3D image segmentation, ... Carole Gee at the University of Bonn, Germany, ... material. Traditional techniques, such as thin-sectioning, require investigators ... to observe internal structures. Dr. Gee, however, has ...
... released today demonstrates how experiences impact genes that influence ... the annual meeting of the Society for Neuroscience and ... science and health, provide new insights into how experience ... addiction and memory formation. The studies focus ...
Cached Biology News:Visualizing the past: Nondestructive imaging of ancient fossils 2Nurture impacts nature: Experiences leave genetic mark on brain, behavior 2
(Date:12/19/2014)... Dec. 18, 2014   ISN has released ... Performance Indicators publication series. With data aggregated ... reported in 2013 within its online contractor management platform, ... key performance indicator (KPI) statistics. The ... publication is available in two industry specific ...
(Date:12/17/2014)... 17, 2014 Achim Noack has been ... Stoller Group. In this position, Noack will assist Jerry ... matters, develop marketing strategy and supervise global marketing management ... “Achim has tremendous knowledge and experience in the crop ... “His experience and innovative thinking will be a great ...
(Date:12/17/2014)... 2014 Gene synthesis and bioengineering ... entered into a technology access and services agreement ... DNA2.0’s proprietary protein engineering technology, known as “ProteinGPS®” ... are extremely excited that the global leader ADM ... proprietary bioengineering technology has now been validated through ...
(Date:12/17/2014)... SAN FRANCISCO, Calif. , Dec. 17, 2014 ... results of a Phase 2 study evaluating the ... the treatment of patients with severe, chronic itch ... current standard of care, including topical steroids and ... was percent change in Visual Analog Scale (VAS) ...
Breaking Biology Technology:ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4
... Most mechanical resonators damp (slow down) in a well-understood ... and his research group at the Catalan Institute of ... and carbon nanotubes exhibit nonlinear damping, opening up exciting ... In an article to be published in Nature ...
... TEI Biosciences Inc. was named a winner of ... Business Association of New England (SBANE) . TEI was ... winners in the for-profit category. Former winners of ... service and retail/distribution, and include Genzyme, Staples, iRobot, PictureTel, and ...
... ROCKVILLE, Md., May 13, 2011 Novavax, Inc. (Nasdaq: ... Frederick Driscoll, Chief Financial Officer of Novavax, will be presenting ... 16, 2011 at 10:30am at The Hard Rock Hotel, Hollywood, ... be accessed via the Company website at www.novavax.com ...
Cached Biology Technology:Exotic behavior when mechanical devices reach the nanoscale 2TEI Biosciences Wins SBANE 2011 New England Innovation Award 2
Synphilin 1 Immunogen: Synthetic peptide corresponding to residues S(829) L E L N G E K D K D K G R T L Q R T(847) of human Synphilin 1. Storage: -20 C, Avoid Freeze/Thaw Cycles...
COMING SOON: Anti-Mouse C5/C5b, Clone BB5.1. Monoclonal Antibody...
fli-1...
... Alpha 1 Acid Glycoprotein ... Goats were immunized with highly ... Freund's adjuvant. The antiserum ... ensure specificity. For Research ...
Biology Products: