Navigation Links
Hypertension and cholesterol medications present in water released into the St. Lawrence River
Date:1/26/2009

This press release is available in French.

Montreal, January 26, 2009 A study conducted by Universit de Montral researchers on downstream and upstream water from the Montreal wastewater treatment plant has revealed the presence of chemotherapy products and certain hypertension and cholesterol medications.

Bezafibrate (cholesterol reducing medication), enalapril (hypertension medication), methotrexate and cyclophosphamide (two products used in the treatment of certain cancers) have all been detected in wastewater entering the Montreal treatment station. However, only bezafibrate and enalapril have been detected in the treated water leaving the wastewater treatment plant and in the surface water of the St. Lawrence River, where the treated wastewater is released.

This study was conducted due to the sharp rise in drug consumption over the past few years. In 1999, according to a study by IMS Health Global Services, world drug consumption amounted to $342 billion. In 2006 that figure doubled to $643 billion. A significant proportion of the drugs consumed are excreted by the human body in urine and end up in municipal wastewater. Chemotherapy products, such as methotrexate, are excreted by the body practically unchanged (80 to 90 percent in their initial form).

Chemotherapy for fish?

The pharmaceutical compounds studied were chosen because of the large quantities prescribed by physicians. "Methotrexate and cyclophosphamide are two products very often used to treat cancer and are more likely to be found in water," says Sbastien Sauv, a professor of environmental chemistry at the Universit de Montral. "Even though they treat cancer, these two products are highly toxic. This is why we wanted to know the extent to which the fauna and flora of the St. Lawrence are exposed to them."

Method and quantities

Professor Sauv's team validated a rapid detection method (On-line SPE-LC-MS/MS ) (1) for pharmaceutical compounds under study in the raw and treated wastewater of the Montreal wastewater treatment plant.

The quantities of bezafibrate and enalapril detected in the raw wastewater, treated wastewater and surface water at the treatment station outlet are respectively 50 nanograms per litre, 35 ng L and 8 ng L for bezafibrate and 280 ng L, 240 ng L and 39ng L for enalapril.

"All in all, these quantities are minimal, yet we don't yet know their effects on the fauna and flora of the St. Lawrence," Professor Sauv explains. "It is possible that some species are sensitive to them. Other ecotoxicological studies will be necessary. As for the chemotherapy products detected in the raw wastewater but not in the treated wastewater, one question remains: did we not detect them because the treatment process succeeded in eliminating them or because our detection method is not yet sophisticated enough to detect them?"

A new threat to the aquatic environment

The release locations of wastewaters treated by the treatment stations are the main source of drug dispersion into the environment. Because of their high polarity and their acid-base character, some of the pharmaceutical compounds studied have the potential to be transported and dispersed widely in the aquatic environment. In Montreal, the wastewater treatment station treats a water volume representing 50 percent of the water treated in Quebec and has a capacity of about 7.6 million cubic metres per day, making it the largest physicochemical treatment station in the Americas. This is why it is important to develop a simple, rapid, precise and inexpensive method, Professor Sauv points out.


'/>"/>

Contact: Julie Gazaille
j.cordeau-gazaille@umontreal.ca
514-343-6796
University of Montreal
Source:Eurekalert

Related biology news :

1. Hypertension develops early, silently, in African-American men
2. Severe gestational hypertension may protect against testicular cancer
3. Hypertension disparity linked to environment
4. Blood pressure response to daily stress provides clues for better hypertension treatment
5. A single mechanism for hypertension, insulin resistance and immune suppression
6. Hypertension treatment effective in reversing vascular damage
7. Rare genetic mutations protect against hypertension
8. Researchers discovery may lead to hypertension treatment
9. Ultra-low-dose aspirin might decrease bleeding severity in portal hypertension
10. Understanding hypertension in African Americans proves elusive
11. New genes present drug targets for managing cholesterol and glucose levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... -- Delta (NYSE: DAL ) customers now can use fingerprints ... Washington National Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington National ... Delta,s biometric boarding pass experience that launched ... into the boarding process to allow eligible Delta SkyMiles Members who are ...
(Date:5/16/2017)...  Veratad Technologies, LLC ( www.veratad.com ), an innovative ... verification solutions, announced today they will participate as a ... thru May 17, 2017, in Washington D.C.,s ... Identity impacts the lives of billions ... evolving digital world, defining identity is critical to nearly ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc., a global expert in ... media edge server, the M820, which features the company,s hybrid codec ... provided by Tera Probe, Inc., will be showcased during the upcoming ... NAB show at the Las Vegas Convention ... Click ...
Breaking Biology News(10 mins):
(Date:9/21/2017)... ... September 21, 2017 , ... Dr. Greg Leyer, Chief ... NV on September 27th. His presentation is at 12:10pm in the Probiotics Resource Center, ... present at SupplySide West and discuss how probiotics have shown impressive data in areas ...
(Date:9/21/2017)... S.C. (PRWEB) , ... September 21, 2017 , ... ... turned bright neon green this month, the response was swift and efficient thanks ... ( RRWQG ). RRWQG is made up of more than 50 stakeholders, including ...
(Date:9/20/2017)... ... 20, 2017 , ... Diversity focused business accelerator, The Refinery , announced ... to uncover the top technology-driven, women-led startups in Boston, MA, New Haven/Hamden, CT, and ... entrepreneurial events going on that week – in Boston, it will be part of ...
(Date:9/20/2017)... ... September 20, 2017 , ... Foresight Institute, a leading ... transformative technologies, announced the winners for the 2017 Foresight Institute Feynman Prizes.These are ... nanotechnology/molecular manufacturing. , Established in 1993 and named in honor of pioneer physicist ...
Breaking Biology Technology: