Navigation Links
Human trials for Streptococcus A vaccine
Date:2/28/2013

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

Severe damage to a patient's heart is just one of the possible long term consequences of rheumatic fever. Former Prime Minister Kevin Rudd has twice had heart surgery to repair damage suffered from rheumatic fever when he was a child.

Professor Michael Good, Principal Research Leader at the Institute for Glycomics has devoted more than 20 years to beating this disease. The key to the vaccine lies in targeting a particular protein found on the surface of Strep A bacteria.

"Previous studies have shown that the vaccine induces a very effective immune response in rabbits and mice," Professor Good said.

"The next important step is to ensure that it is safe and does not cause any adverse effects in people, in particular that the vaccine itself doesn't cause any heart damage."

Professor James McCarthy, Head of the Infectious Diseases program at the Queensland Institute of Medical Research will carry out the year-long trial involving 20 healthy adults.

"Participants will be monitored very closely for the next 12 months," Professor McCarthy said.

"Each volunteer will be given two doses of the vaccine and we'll be watching carefully for any signs of heart problems."

Rheumatic fever is a major issue in remote Aboriginal and Torres Strait Islander communities in northern Australia.

"Infection rates in these remote Queensland communities are among the highest in the world. Nine out of every ten sufferers in this State are Aboriginal or Torres Strait Islander people," Professor Good said.


'/>"/>
Contact: Helen Wright
helen.wright@griffith.edu.au
07-373-54288
Griffith University
Source:Eurekalert

Page: 1

Related biology news :

1. Nearby chimpanzee populations show much greater genetic diversity than distant human populations
2. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
3. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
4. A birds song may teach us about human speech disorders
5. Scientists produce eye structures from human blood-derived stem cells
6. Human noise has ripple effects on plants
7. Did climate change shape human evolution?
8. Harmless human virus may be able to boost the effects of chemotherapy
9. Study resolves debate on human cell shut-down process
10. Fine-scale analysis of the human brain yields insight into its distinctive composition
11. Bartonella infection associated with rheumatoid illnesses in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... , UAE, April 20, 2016 ... be implemented as a compact web-based "all-in-one" system solution ... the biometric fingerprint reader or the door interface with ... of modern access control systems. The minimal dimensions of ... ID readers into the building installations offer considerable freedom ...
(Date:4/13/2016)...  IMPOWER physicians supporting Medicaid patients in ... standard in telehealth thanks to a new partnership with ... IMPOWER patients can routinely track key health measurements, such ... and, when they opt in, share them with IMPOWER ... local retail location at no cost. By leveraging this ...
(Date:3/23/2016)... Massachusetts , March 23, 2016 /PRNewswire/ ... im Interesse erhöhter Sicherheit Gesichts- und Stimmerkennung ... Xura, Inc. (NASDAQ: MESG ), ... bekannt, dass das Unternehmen mit SpeechPro zusammenarbeitet, ... aus der Finanzdienstleistungsbranche, wird die Möglichkeit angeboten, ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... -- The Prostate Cancer Foundation (PCF) is pleased to announce 24 new ... prostate cancer. Members of the Class of 2016 were selected from a pool ... Read More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... STACS DNA ... Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as a ... STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further ...
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
Breaking Biology Technology: