Navigation Links
Human taste cells regenerate in a dish
Date:4/6/2011

I>, they then applied that methodology to a more clinically relevant population humans.

Taking tiny samples of tongue tissue from human volunteers, the researchers first adapted existing techniques to demonstrate that the human taste cells indeed can regenerate in culture.

They went on to show that the new taste cells were functional, maintaining key molecular and physiological properties characteristic of the parent cells. For example, the new cells also were activated by sweet and bitter taste molecules.

"By producing new taste cells outside the body, our results demonstrate that direct stimulation from nerves is not necessary to generate functional taste cells from precursors," said Ozdener.

The establishment of a feasible long-term taste cell culture model opens a range of opportunities to increase understanding of the sense of taste.

"Results from these cells are more likely to translate to the clinic than those obtained from other species or from systems not derived from taste tissue," said Rawson.

The cells also can be used to screen and identify molecules that activate the taste receptors; one such example might be a salt replacer or enhancer.

"The model will help scientists identify new approaches to design and establish cell culture models for other human cells that previously had resisted viable culture conditions," said Ozdener


'/>"/>

Contact: Leslie Stein
stein@monell.org
267-519-4707
Monell Chemical Senses Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Worlds reef fishes tussling with human overpopulation
2. 18th International Academy of Astronautics Humans in Space Symposium
3. In vitro infection and replication of hepatitis E virus in human hepatocytes
4. Human impacts on the marine ecosystems of Antarctica
5. Human virus linked to deaths of endangered mountain gorillas
6. Study indicates vitamin A plays key role in the human body
7. Method reveals new view of human nerve cells, opening door to potential drug targets
8. Humans give prey the edge in food web
9. Mapping human vulnerability to climate change
10. U. Iowa team investigates function of junk DNA in human genes
11. Missing sugar molecule raises diabetes risk in humans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... Increasing adoption in ... to drive biometric systems market in ... According to a recently released TechSci Research ... biometric systems market in Saudi Arabia ... CAGR of over 22% through 2020. The market ...
(Date:4/13/2015)... According to a recently ... & Opportunities, 2020", the global biometrics market is ... till 2020. The biometrics market is garnering attention ... review of biometric management systems. The constant development ... greater efficiency, are resulting in increasing installation of ...
(Date:4/9/2015)... April 9, 2015 Synaptics Inc. (NASDAQ: SYNA ... today that it will report financial results for the ... 2015, after the close of market. The company will ... at 2:00 p.m. PT (5:00 p.m. ET), during which ... participate on the live call, analysts and investors should ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2Synaptics to Report Third Quarter Results on April 23 2
... 19, 2012) A study comparing whether endothelial colony-forming cells ... umbilical cord blood are more proliferative and better for forming ... placenta are more vasculogenic., The study, carried out by researchers ... recent issue of Cell Medicine [2(3)] and is ...
... ON Humans get most of the blame for climate ... natural forces. Now, scientists from the University of Toronto and ... one potential cause of the cooling trend of the past ... chemistry of the world,s oceans. "Seawater chemistry is characterized ...
... enable greater reliance on renewable biomass resources for power ... of biomass with coal offer unique advantages, but also ... available and in development to improve the characteristics of ... peer-reviewed journal from Mary Ann Liebert, Inc. . ...
Cached Biology News:Blood vessel forming potential of stem cells from human placenta and umbilical cord blood 2Scientists connect seawater chemistry with climate change and evolution 2Strategies to improve renewable energy feedstocks 2
(Date:5/28/2015)... London (PRWEB) May 28, 2015 ... Computer Aided Engineering software, announced today it is ... (PSRI). CD-adapco will provide state-of-the-art engineering simulation tools ... share their expertise and experiences in analyzing particle ... industry members and advance the understanding of flow ...
(Date:5/28/2015)... (PRWEB) May 28, 2015 Glenn Keet, ... The Changing Landscape of EMR/EHR Clinical Data Integration with ... taking place in Washington, DC on June 14th-18th. , ... of integrating EMR/EHR systems with EDC, and will examine ... brought by eSource and electronic health records/electronic medical records ...
(Date:5/28/2015)... (PRWEB) May 28, 2015 Global ... a point to ask his audiences if they ... trends including robotics, solar cells, fuel cells, rapid ... printers, advanced battery storage technology, driverless cars, artificial ... high-quality but inexpensive online education. , While ...
(Date:5/28/2015)... Virginia (PRWEB) May 28, 2015 ... LLC announced today that Roger L. Williams, MD, ... consultant. NDA Partners Premier Experts are top tier ... to bring extraordinary value to the company’s clients. ... solutions to help clients successfully develop their medical ...
Breaking Biology Technology:CD-adapco and PSRI Chartering New Course in Particle Flow Simulations 2Clinovo Presents at the DIA 2015 51st Annual Meeting in Washington, DC on June 14th-18th 2Futurist Jack Uldrich to Deliver 4 Keynote Addresses in June 2Former CEO and Chair of the Council of Experts at the USP, Roger L. Williams, MD, Joins NDA Partners as a Premier Expert Consultant 2
... LOUIS, Aug. 27 Missouri Coalition for,Lifesaving Cures ... far-,reaching initiative petition filed last week by opponents ... worded and scientifically unsound that it,would exclude Missourians ... syndromes from its definition of "human." In ...
... Drug Royalty LP 2 (DRC) announced,today the ... worldwide,royalty interest in PEG-INTRON for $92.5M. DRC will ... certain royalty recognition levels be met.,PEG-INTRON (peginterferon alpha-2b), ... is marketed worldwide by Schering-Plough Corporation (SGP). ...
... 27 NovaQuest has,made a strategic investment ... specializing in respiratory,disorders. The investment was part ... million) in the Montreal-based company. Last ... partnering group,of Quintiles Transnational, helps TOPIGEN accelerate ...
Cached Biology Technology:New Initiative Has Shocking Effect: Thousands of Missourians with Abnormal Chromosome Structures Are Not Human 2Drug Royalty Corporation (DRC) Announces Acquisition Regarding PEG-INTRON(R) From Enzon Pharmaceuticals, Inc. (ENZN) 2NovaQuest Advances 'Virtual Development' Model With Strategic Investment in TOPIGEN Pharmaceuticals 2
... The user-friendly Eppendorf Thermomixer R ... preparations that require shaking, heating, and ... greatly expanded its application and temperature ... can each accommodate 24 micro test ...
Mouse monoclonal antibody raised against a partial recombinant PDE2A. NCBI Entrez Gene ID = PDE2A...
... can be used to test the crossreactivity ... sera that are commonly used as blocking ... spots for 19 different protein preparations on ... crossreactivity and species specificity, QC of purified ...
... sufficient materials for 1,464 array sample elements. , , ... , Blocker BSA in PBS (10X): 50 ml , ... Saline: 8 packs , 10% Tween-20: 2 x 10 ... x 25 ml , SuperSignal West Pico Stable Peroxide: ...
Biology Products: